PTR
O-PHOSPHOTYROSINE
Find entries where: PTR
is present as a standalone ligand in 8 entries
is present in a polymer sequence 866 entries
Chemical Component Summary | |
|---|---|
| Name | O-PHOSPHOTYROSINE |
| Synonyms | PHOSPHONOTYROSINE |
| Identifiers | (2S)-2-amino-3-(4-phosphonooxyphenyl)propanoic acid |
| Formula | C9 H12 N O6 P |
| Molecular Weight | 261.168 |
| Type | L-PEPTIDE LINKING |
| Isomeric SMILES | c1cc(ccc1C[C@@H](C(=O)O)N)OP(=O)(O)O |
| InChI | InChI=1S/C9H12NO6P/c10-8(9(11)12)5-6-1-3-7(4-2-6)16-17(13,14)15/h1-4,8H,5,10H2,(H,11,12)(H2,13,14,15)/t8-/m0/s1 |
| InChIKey | DCWXELXMIBXGTH-QMMMGPOBSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 29 |
| Chiral Atom Count | 1 |
| Bond Count | 29 |
| Aromatic Bond Count | 6 |
Drug Info: DrugBank
| DrugBank ID | DB01962? |
|---|---|
| Name | Phosphonotyrosine |
| Groups | experimental |
| Description | An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis. [PubChem] |
| Synonyms | Phosphonotyrosine |
| CAS number | 21820-51-9 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Tyrosine-protein kinase HCK | MGGRSSCEDPGCPRDEERAPRMGCMKSKFLQVGGNTFSKTETSASPHCPV... | unknown | |
| Proto-oncogene tyrosine-protein kinase Src | MGSNKSKPKDASQRRRSLEPAENVHGAGGGAFPASQTPSKPASADGHRGP... | unknown | |
| Mast/stem cell growth factor receptor Kit | MRGARGAWDFLCVLLLLLRVQTGSSQPSVSPGEPSPPSIHPGKSDLIVRV... | unknown |
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 30819 |
| ChEMBL | CHEMBL286939 |
| ChEBI | CHEBI:37788 |
