QUS

(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID

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is present as a standalone ligand in 32 entries

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Chemical Component Summary
Name	(S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID
Synonyms	QUISQUALATE
Identifiers	(2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid
Formula	C₅ H₇ N₃ O₅
Molecular Weight	189.126
Type	NON-POLYMER
Isomeric SMILES	C([C@@H](C(=O)O)N)N1C(=O)NC(=O)O1
InChI	InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
InChIKey	ASNFTDCKZKHJSW-REOHCLBHSA-N

Chemical Details
Formal Charge	0
Atom Count	20
Chiral Atom Count	1
Bond Count	20
Aromatic Bond Count	5

Drug Info: DrugBank

DrugBank ID	DB02999 ?
Name	Quisqualic acid
Groups	experimental
Description	Quisqualic acid is an agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of _Quisqualis chinensis_.
Synonyms	Quisqualic acid Quisqualate
Categories	Amino Acids Amino Acids, Peptides, and Proteins Excitatory Amino Acid Agents Excitatory Amino Acid Agonists Neurotransmitter Agents Oxadiazoles Oxazoles
CAS number	52809-07-1

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Glutamate receptor 2	MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQ...	unknown
Glutamate receptor ionotropic, kainate 2	MKIIFPILSNPVFRRTVKLLLCLLWIGYSQGTTHVLRFGGIFEYVESGPM...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682