RCO

RESORCINOL

Created:	1999-07-08
Last modified:	2020-06-05

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19 entries where RCO is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	14
Chiral Atom Count	0
Bond Count	14
Aromatic Bond Count	6

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Chemical Component Summary
Name	RESORCINOL
Synonyms	1,3-BENZENEDIOL; 1,3-DIHYDROXYBENZENE
Systematic Name (OpenEye OEToolkits)	benzene-1,3-diol
Formula	C₆ H₆ O₂
Molecular Weight	110.111
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	Oc1cccc(O)c1
SMILES	CACTVS	3.341	Oc1cccc(O)c1
SMILES	OpenEye OEToolkits	1.5.0	c1cc(cc(c1)O)O
Canonical SMILES	CACTVS	3.341	Oc1cccc(O)c1
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1cc(cc(c1)O)O
InChI	InChI	1.03	InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H
InChIKey	InChI	1.03	GHMLBKRAJCXXBS-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB11085 ?
Name	Resorcinol
Groups	approved
Description	Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works by helping to remove hard, scaly, or roughened skin. Although it is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of formal therapeutic indication.
Synonyms	1,3-Dihydroxybenzol Resorzin 1,3-Dihydroxybenzene m-hydroxyphenol Resorcinol 1,3-Benzenediol m-Hydroquinone
Brand Names	Clearskin 2 Tinted Blemish Crm Vagicaine Medicated Maximum Strength Up and up vagicaine Vagisil Anti Itch Original Strength Good Sense Vagicaine Anti Itch Acnotex acne Treatment Clearasil Skin Tone Acne Crm Medication Good Neighbor Pharmacy Vagicaine Hemo-pic Assured Feminine Anti-itch Acne Treatment maximum strength CVS BENZOCAINE and RESORCINOL Mazon Medicated Cream Leader Anti-Itch Maximum Strength Glytone Acne Spot Treatment Jon Ares Acne Control Mild Mirakel Pain and Itch Relief Vagicaine Maximum Strength Rezamid Clarifying Mask Rexall Feminine Maximum Strength Anti-itch Benzal Vagisil Creme Regular Strength Budpak Feminine Anti-Itch Smart Sense Vagicaine Maximum Strength VAGISIL Anti-Itch Creme Regular Strength VAGISIL Anti-Itch Medicated Creme Regular Strength Vagisil Anti Itch Maximum Strength VAGISIL Anti-Itch Medicated Creme Maximum Strength Utiliderm Acne Control Quality Choice Vaginal Anti-Itch Maximum Strength Clearasil Daily Clear Tinted Adult Treatment Equaline Vagicaine Maximum Strength Meijer Maximum Strength Vagicaine Anti Itch Vagicaine Leader Anti-Itch Regular Strength Image Essentials Vagicaine Rite Aid Original Strength Vagicaine Vagicaine Maximum Strength Anti-Itch Cream Signature Care Vagicaine Maximum Strength Feminine Anti-Itch Family Wellness Leader Regular Strength Anti-Itch Adult Acnomel Clearasil Daily Clear Adult Tinted Acne Treatment Resinol Thunas Eczema Ont Adult Acnomel Tinted Acne Aid Gel Feminine Anti-Itch Creme Acnomel Skin Tone Cream DG Health Feminine Anti-itch Eau Resolutive Soker Equate vagicaine maximum strength Anti-Itch Regular Strength Tinted Acne Treatment Family Wellness Topcare Vagicaine Well at Walgreens Anti-Itch Maximum Strength Leader Maximum Strength Anti-Itch Cvs Acne Treatment Clearasil Vanishing Acne Crm Medication Vagi-cure (maximum Strength) Anti-Itch Medicated Maximum Strength Acne Drying Topical Glytone acne OptimV Anti-Itch Maximum Strength Basic Care Vagicaine Mirakel Glytone acne treatment flesh tinted acne
Indication	Contemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L40069, F61] or as topical antibacterial skin treatment products for conditions like acne, seborrheic dermatitis, eczema, and others [L2746, L2745, L2744, L40069, F61].
Categories	Anti-Acne Preparations Anti-Acne Preparations for Topical Use Anti-Infective Agents Anti-Infective Agents, Local Benzene Derivatives Dermatologicals Drugs that are Mainly Renally Excreted Ophthalmologicals Phenols Root Canal Filling Materials Sensory Organs
ATC-Code	D10AX02 S01AX06
CAS number	108-46-3

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Carbonic anhydrase 12	MPRRSLHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSWSKKYPSC...	unknown	inhibitor
Carbonic anhydrase 2	MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVS...	unknown	inhibitor
Carbonic anhydrase 14	MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDI...	unknown	inhibitor
Prostaglandin G/H synthase 1	MSRSLLLWFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFG...	unknown	inhibitor
Thyroid peroxidase	MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLV...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	5054
ChEMBL	CHEMBL24147
ChEBI	CHEBI:27810
CCDC/CSD	GAJROB, HOLKAW, IGIZEG01, KAJFEJ, IGIZAC, ACOYOG01, EDAZOB, EDAYIU, ABEKUN03, ABEKUN02, ABELAU06, ABEKUN04, HOPKED, IGIZEG, ABEKUN01, DUVHAE01, ACOYOG, DEGQUE, ABELAU03, ABELAU02, ABELAU01, EJIXUQ, DOGCIO, ABELAU04, EBIMIM, ABELAU05, BODSAO, KIHZAD, ANUNED, GAVBAI, KEXHUR, FOSFOK, AXEZIM, ABEKUN, KEXJIH, ABELAU, DUVHAE, JORBEA, COZZUN, ABELIC, ASORIL, ITUJOX, AXOGIE, GIHBUW, CEKBOJ, BULLAX, KIJLAS, IMIWAF, IYAZEQ