RCO

RESORCINOL

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is present as a standalone ligand in 19 entries

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Chemical Component Summary
Name	RESORCINOL
Synonyms	1,3-BENZENEDIOL; 1,3-DIHYDROXYBENZENE
Identifiers	benzene-1,3-diol
Formula	C₆ H₆ O₂
Molecular Weight	110.111
Type	NON-POLYMER
Isomeric SMILES	c1cc(cc(c1)O)O
InChI	InChI=1S/C6H6O2/c7-5-2-1-3-6(8)4-5/h1-4,7-8H
InChIKey	GHMLBKRAJCXXBS-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	14
Chiral Atom Count	0
Bond Count	14
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB11085 ?
Name	Resorcinol
Groups	approved
Description	Resorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborrheic dermatitis, eczema, psoriasis, corns, calluses, and warts. It exerts a keratolytic activity. Resorcinol works by helping to remove hard, scaly, or roughened skin. Although it is primarily indicated for use as a topical application, resorcinol also possesses a well-documented anti-thyroidal activity that is generally not relied upon for any kind of formal therapeutic indication.
Synonyms	m-Hydroquinone Resorcinol 1,3-Dihydroxybenzene Resorzin 1,3-Dihydroxybenzol 1,3-Benzenediol m-hydroxyphenol
Brand Names	Rexall Feminine Maximum Strength Anti-itch Eau Resolutive Soker Adult Acnomel Glytone acne Vagisil Anti Itch Maximum Strength Cvs Acne Treatment Resinol Mirakel Rite Aid Original Strength Vagicaine VAGISIL Anti-Itch Medicated Creme Regular Strength Acne Drying Topical Feminine Anti-Itch Creme Leader Regular Strength Anti-Itch Equate vagicaine maximum strength Vagisil Anti Itch Original Strength Good Sense Vagicaine Anti Itch Topcare Vagicaine VAGISIL Anti-Itch Medicated Creme Maximum Strength Vagicaine Medicated Maximum Strength Acnomel Skin Tone Cream Equaline Vagicaine Maximum Strength Jon Ares Acne Control Mild Acne Treatment maximum strength CVS Glytone Acne Spot Treatment Hemo-pic Mazon Medicated Cream Rezamid VAGISIL Anti-Itch Creme Regular Strength Quality Choice Vaginal Anti-Itch Maximum Strength Smart Sense Vagicaine Maximum Strength Tinted Acne Treatment Vagicaine Maximum Strength Clearasil Vanishing Acne Crm Medication Clearasil Daily Clear Adult Tinted Acne Treatment Vagicaine Mirakel Pain and Itch Relief Leader Anti-Itch Maximum Strength Image Essentials Vagicaine Leader Maximum Strength Anti-Itch Assured Feminine Anti-itch Adult Acnomel Tinted Leader Anti-Itch Regular Strength Meijer Maximum Strength Vagicaine Vagi-cure (maximum Strength) Utiliderm Acne Control Good Neighbor Pharmacy Vagicaine Anti-Itch Medicated Maximum Strength Family Wellness Budpak Feminine Anti-Itch Clearskin 2 Tinted Blemish Crm Glytone acne treatment flesh tinted acne Thunas Eczema Ont Anti Itch Clarifying Mask Up and up vagicaine Basic Care Vagicaine DG Health Feminine Anti-itch Acne Aid Gel BENZOCAINE and RESORCINOL Anti-Itch Regular Strength Maximum Strength Feminine Anti-Itch Family Wellness Clearasil Skin Tone Acne Crm Medication Acnotex acne Treatment OptimV Anti-Itch Maximum Strength Clearasil Daily Clear Tinted Adult Treatment Benzal Vagisil Creme Regular Strength Signature Care Vagicaine Well at Walgreens Anti-Itch Maximum Strength Vagicaine Maximum Strength Anti-Itch Cream
Indication	Contemporary therapeutic uses for resorcinol primarily revolve around the use of the phenol derivative as an active ingredient in topical antiseptics [L2745, L2744, L40069, F61] or as topical antibacterial skin treatment products for conditions like acne, seborrheic dermatitis, eczema, and others [L2746, L2745, L2744, L40069, F61].
Categories	Anti-Acne Preparations Anti-Acne Preparations for Topical Use Anti-Infective Agents Anti-Infective Agents, Local Benzene Derivatives Dermatologicals Drugs that are Mainly Renally Excreted Ophthalmologicals Phenols Root Canal Filling Materials Sensory Organs
ATC-Code	D10AX02 S01AX06
CAS number	108-46-3

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Thyroid peroxidase	MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLV...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource Name	Reference
PubChem	5054
ChEMBL	CHEMBL24147
ChEBI	CHEBI:27810
CCDC/CSD	GAJROB, HOLKAW, IGIZEG01, KAJFEJ, IGIZAC, ACOYOG01, EDAZOB, EDAYIU, ABEKUN03, ABEKUN02, ABELAU06, ABEKUN04, HOPKED, IGIZEG, ABEKUN01, DUVHAE01, ACOYOG, DEGQUE, ABELAU03, ABELAU02, ABELAU01, EJIXUQ, DOGCIO, ABELAU04, EBIMIM, ABELAU05, BODSAO, KIHZAD, ANUNED, GAVBAI, KEXHUR, FOSFOK, AXEZIM, ABEKUN, KEXJIH, ABELAU, DUVHAE, JORBEA, COZZUN, ABELIC, ASORIL, ITUJOX, AXOGIE, GIHBUW, CEKBOJ, BULLAX, KIJLAS, IMIWAF, IYAZEQ

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.

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RCO

RESORCINOL

Chemical Component Summary

Chemical Details

Drug Info: DrugBank

Drug Targets

Related Resource References