SIN
SUCCINIC ACID
Find entries where: SIN
is present as a standalone ligand in 285 entries
as a non-polymer is covalently linked to polymer or other heterogen groups 13 entries
is present in a polymer sequence 27 entries
Chemical Component Summary | |
|---|---|
| Name | SUCCINIC ACID |
| Identifiers | butanedioic acid |
| Formula | C4 H6 O4 |
| Molecular Weight | 118.088 |
| Type | NON-POLYMER |
| Isomeric SMILES | C(CC(=O)O)C(=O)O |
| InChI | InChI=1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8) |
| InChIKey | KDYFGRWQOYBRFD-UHFFFAOYSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 14 |
| Chiral Atom Count | 0 |
| Bond Count | 13 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB00139? |
|---|---|
| Name | Succinic acid |
| Groups |
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| Description | A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851) |
| Synonyms |
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| Brand Names |
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| Indication | For nutritional supplementation, also for treating dietary shortage or imbalance |
| Categories |
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| CAS number | 110-15-6 |
Drug Targets
| Name | Target Sequence | Pharmacological Action | Actions |
|---|---|---|---|
| Succinate-semialdehyde dehydrogenase, mitochondrial | MATCIWLRSCGARRLGSTFPGCRLRPRAGGLVPASGPAPGPAQLRCYAGR... | unknown | inhibitor |
| Succinate receptor 1 | MLGIMAWNATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIF... | unknown | |
| Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | MAALLLRHVGRHCLRAHFSPQLCIRNAVPLGTTAKEEMERFWNKNIGSNR... | unknown | substrate |
| Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | MSGVRGLSRLLSARRLALAKAWPTVLQTGTRGFHFTVDGNKRASAKVSDS... | unknown | substrate |
| Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial | MASPVAAQAGKLLRALALRPRFLAAGSQAVQLTSRRWLNLQEYQSKKLMS... | unknown | product of |
| View More | |||
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison
T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS.
Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 21952380, 1110 |
| ChEMBL | CHEMBL576 |
| ChEBI | CHEBI:15741 |
| CCDC/CSD | EFAPUY, DIKCIK, DICYIA, ENICOU01, FADGIC, CIRXAD, DUWLAK, EXIPEH, CEJXOF, GABZUF, GAWLOG, AXUFIJ, BULGEU, DILVAX, FIDCIG, HAGNEJ, GESBAJ, FADGIC03, GALBIF, BIQTON, DUFJIA01, CUVDUT, DUFJIA, BICQAH, ENICOU, CIWFUL, EWOZIZ, FADGIC02, FOTFOL, DOSZAO, ACESUY, EMAPIT, DUZPAQ, GOKBAL, FAGXOB, AVEKAN, CUJMIE, EXIPEH01, EYECIW, GADBEV, GOKBAL01, CAKZUL, BEPTIB, FOTDID, FOTDAV, BZASUC, EVATAZ, EZAQOO, AQOMIF |
| COD | 7214503, 7217968, 2019656, 7214504, 7217969, 7214484, 7217949, 4507999, 4508000, 7214505, 7217970, 7214485, 7217950, 7214501, 7217966, 4507998, 4508001, 4508002, 4508003, 7214502, 7217967, 7214486, 7217951, 7214483, 7217948, 7214500, 7217965, 7214481, 7217946, 7208190, 7205837, 4501989, 7214482, 7217947, 7214480, 7217945, 7205836, 2101616, 2207898, 1520258, 7200947, 7208516 |
