SRO

SEROTONIN

Find entries where: SRO

is present as a standalone ligand in 44 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 3 entries

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Chemical Component Summary
Name	SEROTONIN
Synonyms	3-(2-AMINOETHYL)-1H-INDOL-5-OL
Identifiers	3-(2-aminoethyl)-1H-indol-5-ol
Formula	C₁₀ H₁₂ N₂ O
Molecular Weight	176.215
Type	NON-POLYMER
Isomeric SMILES	c1cc2c(cc1O)c(c[nH]2)CCN
InChI	InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
InChIKey	QZAYGJVTTNCVMB-UHFFFAOYSA-N

Chemical Details
Formal Charge	0
Atom Count	25
Chiral Atom Count	0
Bond Count	26
Aromatic Bond Count	10

Drug Info: DrugBank

DrugBank ID	DB08839 ?
Name	Serotonin
Groups	investigational nutraceutical
Description	For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.
Synonyms	5-HT sérotonine thrombotonin thrombocytin Enteramine Serotonin 3-(2-Aminoethyl)-1H-indol-5-ol 5-Hydroxytryptamine Serotonin hydrochloride
Categories	Amines Antidepressive Agents Autacoids Biogenic Amines Biogenic Monoamines Biological Factors Central Nervous System Depressants Complex Mixtures Endopeptidases Heterocyclic Compounds, Fused-Ring Indoles Inflammation Mediators Neurotransmitter Agents Serine Proteases Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin Agents Serotonin Receptor Agonists Snake Venoms Toxins, Biological Tryptamines Venoms Viper Venoms
CAS number	50-67-9

Drug Targets

Name	Target Sequence	Pharmacological Action
Sodium-dependent serotonin transporter	METTPLNSQKQLSACEDGEDCQENGVLQKVVPTPGDKVESGQISNGYSAV...	unknown
5-hydroxytryptamine receptor 2A	MDILCEENTSLSSTTNSLMQLNDDTRLYSNDFNSGEANTSDAFNWTVDSE...	unknown
5-hydroxytryptamine receptor 3A	MLLWVQQALLALLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVR...	unknown
5-hydroxytryptamine receptor 3B	MLSSVMAPLWACILVAAGILATDTHHPQDSALYHLSKQLLQKYHKEVRPV...	unknown
Synaptic vesicular amine transporter	MALSELALVRWLQESRRSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYS...	unknown
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682