TIZ
(1R)-1-[4-(AMINOCARBONYL)-1,3-THIAZOL-2-YL]-1,4-ANHYDRO-D-RIBITOL
Find entries where: TIZ
is present as a standalone ligand in 2 entries
Chemical Component Summary | |
|---|---|
| Name | (1R)-1-[4-(AMINOCARBONYL)-1,3-THIAZOL-2-YL]-1,4-ANHYDRO-D-RIBITOL |
| Synonyms | TIAZOFURIN |
| Identifiers | 2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-thiazole-4-carboxamide |
| Formula | C9 H12 N2 O5 S |
| Molecular Weight | 260.267 |
| Type | NON-POLYMER |
| Isomeric SMILES | c1c(nc(s1)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)C(=O)N |
| InChI | InChI=1S/C9H12N2O5S/c10-8(15)3-2-17-9(11-3)7-6(14)5(13)4(1-12)16-7/h2,4-7,12-14H,1H2,(H2,10,15)/t4-,5-,6-,7-/m1/s1 |
| InChIKey | FVRDYQYEVDDKCR-DBRKOABJSA-N |
Chemical Details | |
|---|---|
| Formal Charge | 0 |
| Atom Count | 29 |
| Chiral Atom Count | 0 |
| Bond Count | 30 |
| Aromatic Bond Count | 0 |
Drug Info: DrugBank
| DrugBank ID | DB13243? |
|---|---|
| Name | Tiazofurine |
| Groups | experimental |
| Description | Tiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5¡¯-monophosphate (IMP) dehydrogenase [A174991]. |
| Synonyms |
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| Categories |
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| ATC-Code | L01XX18 |
| CAS number | 60084-10-8 |
Related Resource References
| Resource Name | Reference |
|---|---|
| PubChem | 457954 |
| ChEMBL | CHEMBL108358 |
| ChEBI | CHEBI:90239 |
| CCDC/CSD | BOBNEL10 |
