UFP

5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE

Find entries where: UFP

is present as a standalone ligand in 30 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 5 entries

is present in a polymer sequence 6 entries

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Chemical Component Summary
Name	5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE
Identifiers	[(2R,3S,5R)-5-(5-fluoro-2,4-dioxo-pyrimidin-1-yl)-3-hydroxy-oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₉ H₁₂ F N₂ O₈ P
Molecular Weight	326.172
Type	DNA LINKING
Isomeric SMILES	C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)F)COP(=O)(O)O)O
InChI	InChI=1S/C9H12FN2O8P/c10-4-2-12(9(15)11-8(4)14)7-1-5(13)6(20-7)3-19-21(16,17)18/h2,5-7,13H,1,3H2,(H,11,14,15)(H2,16,17,18)/t5-,6+,7+/m0/s1
InChIKey	HFEKDTCAMMOLQP-RRKCRQDMSA-N

Chemical Details
Formal Charge	0
Atom Count	33
Chiral Atom Count	3
Bond Count	34
Aromatic Bond Count	0

Drug Info: DrugBank

DrugBank ID	DB03761 ?
Name	5-fluoro-2'-deoxyuridine-5'-monophosphate
Groups	experimental
Synonyms	F-dUMP 5-fluorodeoxyuridine monophosphate 5FdUMP 5-fluoro-2'-deoxyuridine-5'-monophosphate
Categories	Deoxyribonucleotides Deoxyuracil Nucleotides Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Pyrimidine Nucleotides Pyrimidines Uracil Nucleotides
CAS number	134-46-3

Drug Targets

Name	Target Sequence	Pharmacological Action
Thymidylate synthase	MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRC...	unknown
Thymidylate synthase	MLEQPYLDLAKKVLDEGHFKPDRTHTGTYSIFGHQMRFDLSKGFPLLTTK...	unknown
Thymidylate synthase ThyX	MKIDILDKGFVELVDVMGNDLSAVRAARVSFDMGLKDEERDRHLIEYLMK...	unknown
Thymidylate synthase 1	MTQFDKQYNSIIKDIINNGISDEEFDVRTKWDSDGTPAHTLSVISKQMRF...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682