UTP

URIDINE 5'-TRIPHOSPHATE

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is present as a standalone ligand in 124 entries

as a non-polymer is covalently linked to polymer or other heterogen groups 2 entries

is present in a polymer sequence 5 entries

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Chemical Component Summary
Name	URIDINE 5'-TRIPHOSPHATE
Identifiers	[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methyl (hydroxy-phosphonooxy-phosphoryl) hydrogen phosphate
Formula	C₉ H₁₅ N₂ O₁₅ P₃
Molecular Weight	484.141
Type	NON-POLYMER
Isomeric SMILES	C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@@](=O)(O)O[P@@](=O)(O)OP(=O)(O)O)O)O
InChI	InChI=1S/C9H15N2O15P3/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1
InChIKey	PGAVKCOVUIYSFO-XVFCMESISA-N

Chemical Details
Formal Charge	0
Atom Count	44
Chiral Atom Count	6
Bond Count	45
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB04005 ?
Name	Uridine 5'-triphosphate
Groups	investigational experimental
Description	Uridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
Synonyms	Uridine triphosphate Uridine 5'-triphosphate
Categories	Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Pyrimidine Nucleotides Pyrimidines Ribonucleotides Uracil Nucleotides
CAS number	63-39-8

Drug Targets

Name	Target Sequence	Pharmacological Action
Uridine-cytidine kinase 2	MAGDSEQTLQNHQQPNGGEPFLIGVSGGTASGKSSVCAKIVQLLGQNEVD...	unknown
Genome polyprotein	MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATR...	unknown
Genome polyprotein	MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRAPR...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682