VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152 ?
Name	Thiamine
Groups	investigational nutraceutical vet_approved approved
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Thiamine chloride Thiamine mononitrate Vitamin B1 Thiamine Tiamina Antiberiberi factor thiamine(1+) ion thiaminium thiamine(1+) Thiaminum Thiamine hydrochloride Thiamin Aneurin
Brand Names	Dialyvite Supreme D PNV Prenatal Vitamin Plus Vitamin A Super Vitalex Ampoule Buvable Vita-Pac PrePLUS Stress Tab With Iron and Vitamin E Active OB Stress Formula + Iron Maintain Multiple Vitamin & Minerals Vitafol Ultra Hemarexin Tab Maltlevol Liq Childrens Chew Multi Vitamin Tab Multi Vitamin Drops with Fluoride and Iron Multi Vitamins & Minerals Orti B Orifer F Se-Care Conceive B C Antistress Cap Formula Hh Prenatal Vitamin and Mineral Supplement -tab One Daily Vitamin and Mineral Dietary Supplement Multivitamins and Minerals Tablets Chewable Adult Multivitamins With Minerals Livron Plus Ampoule Mor-vites Tab Stress Complex 600 Avec Vit E Cuivre Zinc Virt-Bal DHA Plus Vitogen B Stress C Vit E Zinc & Cop Materna Hemocyte Plus Surbex 500 Filmtab MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Foltabs Prenatal Paramettes Chewable Multivits With Iron Tab Opti-manganese + B1 + C Caplet Multiple Vitamins and Minerals Tab Thiamine Hydrochloride Inj 100mg/ml USP Revitalize Multi-vitamin and Mineral Complex vitaMedMD One Rx WesCap-C-DHA High Potency Multivitamins & Minerals Caplets Thiamine HCl Inj 100mg/ml Tricare Prenatal Quick Dissolve Vit B Complex Ctr PreTAB RE Nata OB NEONATAL Complete SetonET-EC Vol-Nate Ventrixyl Multi-Vitamin Fluoride Drops Vitachrom Gc Z Bec Tab Multivitamins and Multiminerals Formula Regular Tablet Revit Multi-vitamins and Minerals B-50 Hi Potency B Vitamins Tab B1 Tab 100mg Duet DHA 400 ec MVC-Fluoride Methaver Animal Shapes 50 Plus Multiple Vitamins & Minerals Multi - N.T.O.x Formula - Tab Vitamin B1 OB Complete DHA Multi-Vit with Fluoride Vitamin B1 Tab 100mg Card-floe II Tab Geritol Liquid Timed Release B-complex 50 Prometa Vtb Vitamin and Mineral Supplement Vitamine B1 Tab 100mg USP Garfield Chewable Multivitamins Tab Childrens Chewable Tab Hi Potency Multi Tab Super-pote Vitamin Supplement Multitam Vita-Rx Diabetic Vitamin Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Tricare Prenatal Compleat Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Balanced B-50 B-complex Vitamins Tab CitraNatal 90 DHA Kimchi Vitamin chewable multivitamin Multiple Vitamins Plus Iron - Tab Vita Vim With Beta Carotene-caplet Duet DHA 400 Leritone Junior Vitafol OB Caplet O-Cal FA multivitamin Prenatal Formula Tab For-2 Formula Lf Forty Plus Vitamin Supplement Complete Natal DHA Maxi 10 Tab Cavan Heme OB THIAMINE HYDROCHLORIDE injection, solution Livron Plus Tab B-complex Tablets Vit B1 Ctr Srt 100mg Complete Multivitamins and Minerals Tablets Timed Release Vitaday Junior Tab Mega Plex IV - Pck Virt-Tabs Permathene-12 - Caplet B-complex-50 Tab Vita-worth B-complex Tablets B-50 Complex Tab DuetDHA Balanced Hypo Vites Tab Folivane-OB Trinatal GT Zoo Chews Multivitamins W Iron Men's 50+ Se-Plete DHA Multivit with Fluoride O-Cal Prenatal Vitamin Doctor's Choice Brand for Men PreGen DHA B Complex W C and B12 Inj C-Nate DHA Folika-T Foltabs Prenatal Plus DHA Provida DHA Vitafol-OB Plus DHA Prenatal Supplement Plus DHA B Complex With C 300mg Tab Children's Chewable Multi Vitamins With Iron Tablets Hi Potency B Complex W Chelated Minerals Ventrixyl Fe Vitrexate Betaxin Cavan Prenatal Azesco Complete One-A-day - Tab Prenatal Vitamins and Minerals Tablets Protect Plus SO 60 PureVit DualFe Plus M.V.I. Pediatric Multivitamin with Fluoride Pregvit Folic 5 DuetDHA Complete Vasodyn Tab Vitamin and Mineral Supplement - Liq Mangadyn Multicaps Bugs Bunny and Friends Multiple Vitamins Children's Chewable Tab B6 Plus Tab Kanga-B Vitamin B Group + C Nutra Boost B-complex Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Dexivite Se-Natal One Tricare Prenatal DHA One With Folate Provida OB Virt-Caps Liqui B Complex Plus B Virol B-100 Hi Potency B Vitamins Tab Escavite D Folic-K B-complex With Vitamin C, Biotin, Folic Acid Multi Vitamin and Mineral vitamin Nephrocaps RayaVit VitaPhil Aide B 6 Plus Adult Formula 50+ Fortamines 10 Capsules Multi-vitamines Enfants Comprime Orange Flavored Crystal Chews Tab Stress Formula Tab Preplus Vitamin & Mineral Formula 1 Dietary Supplement Lipo-B-C Tab Vitamine Du Groupe B Plus Fer - Liq Beminal With C Fortis Pws Hi Potency Stress B Tension With C PureFe OB Plus Vitrexate FE bioJET Super Kids Chewable Multivitamin Multimineral (chewable Tablets) Kenwood Liquid Supplement PreQue 10 P.R.O. Complex B50 Complex AzesChew Low Potency B Complex Tab Pediatric Infuvite Multiple Vitamins Sopalamine 3b Plus Fibrik Vitamin B Complex + C 600mg Tab Zeldana Se-Natal 19 Chewable Childrens Chewable Multivitamins W Iron Insur-all Vitamin Supplement Natalvirt 90dha Hormodausse Plus Calc Et D Tab Renate B Compound 50mg Tab Megavites Tab Reno Caps Liqui Vita Hi Potency B52 B Complex Tab Inatal Advance Enrich Core Pack - Children Vitamin and Mineral Supplement L.C. Supplement Vitamin B Tablets Iron Polysaccharides Folic Acid DHA Natavite Vitamin B1 Tab 2mg USP Multi Tabs B-50 Complex Stress Formula B-comp + 500mg Vit C Tab Childrens Chewable Vitamin Tab Multi-Vitamin Fluoride and Iron Drops Soluvit N B With C 500 Cap Vitamin B Complex 50 Multivitamins and Minerals for Men For Kids Only Chewable Multivit. Plus Iron Swical-energy 3e Age Super Charged Energy Multi Plex II - Tab Complete One A Day Tab Childrens Chewable Vitamins Floriva Plus Stress Formula Multivitamin Tablets USP Multivitamines RE FAC-x Vitamines Et Mineraux Enfants 970 Formula F L W Marnatal F PNV Ferrous Fumarate Docusate Folic Acid Ferra Naka Plus Vitamins Prenatryl B-100 Complex Tablets Children's Multivitamins Maltlevol 12 Liq Paramettes Syrup Multi-vitamins With Minerals Pro His Mint Chela Iron Plus C,b Complex Virt-Advance Junior Multi Vitamins - Regular Multiple Vitamins & Minerals Tablets Prenatvite Complete Children's Chew Multi & Min Tab One Per Day Vitamin and Mineral Dietary Supplement Pnv-OB-dha Ultra Enerforce MultiVitamin, Iron and Fluoride Drops Multivitamins and Minerals - Complete Multi 12 Injection Poly-Vitamin with Fluoride Multiple Vitamins - Tablet Phytofortis + Calcium A-D Triveen-Duo DHA Vitamin B Compound Tab Vitamin B Compound With Vitamin C Fortis Capsule Dtc TL-Fluorivite Lorid Multi-Vitamin Drops with Fluoride and Iron Thrivite 19 Vitaday Tab Children Choice Multivit Chewable Tab Floradix Formula Liq Vitramyn One Daily VITES Concept DHA Hemarexin Amp Gtf-vitamin-minerals & Pancreatin Tab Infant Multivitamin Drops Meplex T 750 Poly-Vite Pediatric Oral Solution Pregvit Q.T. #4 Vitamin and Mineral Dietary Supplement Swical-energy-2 Trinaz Multi Enfants Tab Paire OB Plus DHA One-A-day Advance Fem - Tablets Thiamine Hydrochloride Injection, USP Virt Nate Vitabanks Vitamin Tab B-complex 100 Vitamines Et Mineraux Nrg Plus Liq B Stress C + Iron & Vite Feminique W Iron and Calcium Tab Obstetrix EC Stress Tab Prenatal Plus Multivitamin Plus DHA MiniCaps Venexa Complexe B 75mg PreNatal Vitamins Plus Multi Vitamin & Minerals Dalivit B-100 Caps Multiple Vitamins Tab Vitamin B Complex W C Tab Cavan Folate DHA Thiamine Hydrochloride PM Caps Stress Formula Vitamin B Complex Plus C 300mg Timed Release Central-vite 18 Essential Children's Chewable Vit and Min Tab Virt Vite GT Multi-12 Pediatric Somarexin and C 1000 Chewable Multiple Vitamins Plus Iron Tab Toni Com Liq Zalvit Cedevita Plus Vitamin Supplement H.W. Children's Chewable Multi Vit & Mineral Multi Vitamin with Fluoride B-complex Tab Children's Chewable Multi Vit W Iron Multiple Vitamins and Minerals Capsules Prenatal Supplement - Tab Multivitamin & Minerals (iron Free) Everyday Multiple Vitamins With Iron Multi-Nate 30 B-Combo B50 B Complex Tab Quflora FE Pediatric Drops Childrens Chewable Multiple Vitamins Plus Fe Davimet with Iron Trinatal Rx 1 Maxine Vitamin and Mineral Supplement Se-Natal 19 Kindervites Master Key Multi Vitamin Multi Mineral Formula 2 Virt-PN HemeNatal OB plus DHA One-A-day Advance Men's Vita-amine Cap 100mg Vitamin B-Complex Dexatran Formula D.S. Multra Plex Ribotin-E Maxum Multi-vite Super Multi Prenatal Mega Antioxidant Vp-heme Ob Keylosa Vitamin B Complex W C 300mg Tab Xyzbac Supravite C 1000 Twin G.F. Powder Nutri-Tab OB Prenatvite Tonicol Et A-D-C Ampoules/comprimes C. Vit-min Formula Multi Vitamines - Liq Fortistress Tab OB Complete Prenatal Children Choice Multivitamin W Iron Chew Tab Foliflex Fortamines-10 Comprimes Surbex-500 With Zinc VitaXyme TRONVite Formula O.C. INATAL Ultra Prenatal Vi-min Niva-Plus PNV-First Stress Formula Multi-B Comp + 500mg Vit C Cap Multitabs Nata Komplete For Kids Only Chewable Multivitamins - Tab Multi-Vitamin with Fluoride TriAdvance Vitamin B Complex + C 300mg Cap Vitaphil 90 DHA Antlerviron Prenatol-M Maxi 6 Liq Alsimine W Vitamins A D B-plex Vit B Complex Plus Vit C 550mg Vit-HA Multi Vitamin and Zinc Supplement CitraNatal Essence Vitamin B Complex Plus 300mg Vitamin C Super Daily No 2 Synergistic Manganese Capsules Zatean-Pn Tandem OB Am Caps B Complex 50+ Caplet For Kids Only Chewable Multivitamins Neo Vites Tab Vitranol Fe Elite OB Prenatal Multivitamin Mycelized Childrens Multi-vitamin Liq Vitafol One Vital Be-100 VIL-Rx Nutrol-B-complex Premium Prenatal - Tablets Derma-force B-100 Vitamin Supplement Glyco Lite Ect TL-Care DHA Ultra Hr Stress B Complex With C, E & Iron Multi-kid Flintstones Multiple Vitamins Plus Iron Thiamine Hydrochloride Injection USP, 100mg/ml Floriva Vitafer - Liq Paramettes Chewable Multivitamins Plus Iron Vitamin B1 100mg Tablet Phytovim Cap Childrens Multiple Vit and Min Chew Tab Dialyvite with Zinc Tendera-OB Vita-vim With Beta-carotene - Tab B Complex Tablets Prim - Royal P.M.T. 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Complex Vita Balance 2000 Bewon Elixir Potassium Plus Vit B Complex Focalgin CA Bal-Care DHA Neonatal Plus Vitamin Prevital Tab Chewable Multiple Vitamins for Children Super Stress Mega B Plus 1000mg Vit C Tab B 50 Capsules Select-OB Plus DHA Prenatal Supplement Plus DHA P.N.P. Vitamin Drink Prenatal Vitamins Plus Phosthenine Vitamines Et Fer (ampoules Buvable) Beminal W C Fortis Inj Chewable Multivitamins Plus Iron Lipovite MI-Vite RX Multinate DHA Stress B Complex With C, E and Iron Tab Vitamin B Cpd W Vit C Tab Megavite Rx NESTABS Prenatal Multi-vitamin/Mineral Supplement Multi #2 Kaydia Patch Children's Chewable Multivitamins With Minerals Materna-tab High Potency Vitamin B Complex + C Tab Cavan Alpha Wellness Formula Complex-75 Somavit Brand Vitamins and Minerals Complex Trinatal Ultra Vitafol Fe Plus Bal-Care DHA Essential Multi Flow Tablets Multivitamins W Minerals Extra Strength Liqui B Complex Prenatvite Plus Prena1 Plus Vitamin B Complex Stress B Complex With C,e, Zinc and Copper Complete Mega B Complex 5 - Pwr Prenatal Vitamins Plus Low Iron Ziphex Multiple Vitamins W Minerals Tab Viva Kids - Tab Vitamines Pour Bebes Et Enfants Total Living Concepts Formula One - Tab Vol-Plus Only One - Tablet Mebolic C-force NataFort Nephron FA Extra P.N. 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Vitamin and Mineral Drink Mix Multi B Supravite Stress Avec Vit E V & M Vitamin and Mineral Supplement Poly-Vi-Flor with Iron Vigo Multivitamins Drops/lozenge Vitamin B + C Cap Multitol-M Multiple Vitamin Tab Vitamin B Complex 100 Osteo-force Beminal With C Fortis Cap Dayavite Dothelle DHA Balanced B-100 B-complex Vitamins Tab Adult Infuvite Multiple Vitamins Children's Chewable Multiple Vitamins (chewable Tablets) Infa Drops Multivitamins Multivitamin with fluoride Nitro Vites - Tab Synergistic Manganese Cap Timed Release B Complex 100 Srt Vita-B Zoo Chews Plus Iron Corvita Pregvit Folic 4 N.E.U. Complex Quflora Pediatric Vitamin B Complex 100 Tab Manganese 50mg Plus B1 & E Tab E.S.T. Complex Prenate Elite Men's Multi Master Formula B Plus C 300 mg Animal Shapes w/Iron Chewtabs Vitrexyl B1 400mg Ctr Tab Taron-C DHA Daily-Vite Multi-Vit-Flor NeuroBion Prenatal Plus Vitamins PROTECT IRON Liquid Twin G.F. Powder Vanilla Flavor Vitafol Caplet Bev B-150 Thiamine HCL 100 mg Multi-phyto Capsules Complexe B Compose 75 Stress B-complex Plus Iron With Vitamins C&e Mvc 9 Plus 3 Inj Multivitamin NataChew Folitin-Z Multiple Vitamin Plus Minerals Tab PNV Prenatal Plus Multivitamin Dynam Ampoule Et Tablet Formula Fm Vitamins & Minerals Tab Multi-Vit with Fluoride and Iron Multinate DHA Extra Prenatal Vitamin and Mineral Supplement Vyo Cylate - Pwr Mega Plex III - Pck Virt-Vite Plus Vege Swiss One Multivitamin W Chel Mins Tab Vitafol Plus Women's Biomultiple Vitamin and Mineral Supplement Super Pantoplex Poly-Vi-Sol Timed Release B-complex 100 Fortaplex Inj TL-Folate Supplement De Multivitamines Infusion Arome Fruits Rouges 24 Multivitamins + Minerals Children's Chewable Multi-vitamin Complete With Minerals Children's Multivitamins With Iron Alkadrenergy Tablets Flintstones Multiple Vitamins Gemvites Jr Tab Chewable Livita Children Multivitamines Et Mineraux Junior Regulier CitraNatal Assure Chela Potassium Plus Children's Chewable Multiple Vit.plus Iron Pregnancy Multivitamin Oncovite Multi Vitamin Drops with Fluoride Children's Chewable With Iron Multivitamines Et Mineraux Medi Msm (methyl Sulfonyl Methane) PR Natal 400 ec B-complex 50 Replavite Vita Vim Multivitamins and Minerals Tab B Complex W Vit C W Non-med Yeast&liver Tab M.V.I. Adult Neo Bex Elixir Pregnancy Multivitamin Folic 5 Poly-VI-flor Adeks Tablets Appedrine Children's Vitamins Chewable Multiple Vitamins Plus Iron Tab One Tablet Daily Mens Formula Omniquin Multiple Vitamins With Iron Tablets Garfield Chewable Multivits Plus Iron Tab Abavite Prenatabs FA Timed Release Vita-vim Srt Numark Multivitamins Super B Compound W 500mg Vit C HemeNatal OB Natalvirt Ca Multra With Iron NovaFerrum Multivitamin with Iron Pediatric Drops Multivitamine Davimet with Fluoride Zavitrol Flinstones Multiple Plus Iron Formula Gm B Complex 25mg Vitamin Supplement hormaSAN forte T.R.I. B-plex Src Bugs Bunny Chew Multi Vit Plus Iron Concept OB Escavite Focalgin 90 DHA FolaGent DHA Children's Vitamins W Iron Chewable Hyporyl - Tab Iron, Vit & Min Supp Neo-bex Neonatal Vitamin Stress Tablets Vena-Bal DHA Daily Energy Brand B-complex Century Complete Bewon Elixir 0.05mg/ml Nutrilite Double X Penta-thion Pwr Time Release B 100 Compound - Tablet C.R.T. 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Multi II IV Vi Tab PR Natal 400 Genicin Vita-Q Vol-Care Rx WestGel DHA Paramettes Multivits Plus Iron Tab (teens) Multi Vite Liq Adult Multi-vitamins Infantol Drops MultiVitamin with Fluoride Phytoplex B Liq Prenatal Plus Iron Livita Adults Quflora FE Vitamin B1 100mg Stress B With 1000 Mg Vitamin C Relnate DHA Everyday Multiple Vitamins Balanced B 125 Srt NovaMV Multivitamin Chela-chromium 200 Childrens Chewab Vitamin W Chel Minerals Myhephron Dialysis and Stress Supplement Multivitamines Plus Fer Pour Enfants (chewable Tablets) Senior Multi One Iron Folate Plus Super Vita-vim With Beta-carotene - Tab Multivitamins and Minerals for Young Men Sibergin B - Cap Distilpure Msm Infuvite Pediatric PreferaOB plus DHA Tricare Prenatal DHA One Rx Multivitamin Stress B Complex With C and E Tab Chew.multiple Vits.with Extra C for Children Balanced B100 Pretrate Tonimol Cap Liq Xyzbac G Cavan-EC SOD DHA Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Novel Vita Amladex THIAMINE HCl Vinate AZ Nutrifer Plus Tablets Tini-cal Ampoules One A Day Advance Adults 50+ VP-Vite Rx Allbee With Vitamin C Cap Finazol Gestamine Comprimes Revit Tab Natural Source Spectrum With Beta Carotene Dia-vite PR Natal 430 ec TriphroCaps Vitamin B Complex Tab Vp-pnv-dha Carbassist Tablets Sopalamine/3b Tab Vitamin B-1 Thiamine HCl 100mg Vitamin B Compound W Vit C 250mg Tab Multi Nt-OX Cc II One A Day Tab PNV-Select Swiss One Multi Vit & Chel Min Tab Complete Multivitamins and Minerals for Children B-plex 100 Pnv-VP-U Natal-V RX Multi-vitamin/Multi-mineral Vitamines Et Mineraux Comprimes Sopalamine/3b Plus C Vitafant Vitazyme P.N. Vitamin-mineral Drink Thiamine RenaPlex Chela-manganese 50 Plus TriStart DHA Multivitamin with 0.25 mg Fluoride B Plus C 300mg Timed Release Thiamine HCl Injection - Liq 100mg/ml Venexa FE Escavite Lq Nutri-Tab OB plus DHA DaVITE Mvc 9+4 Inj Thrivite Rx Multivit-liq OBTREX DHA Combo Pack Twin Ultra Liquid Orange Flavor Vita B Complex Tab Revival 1 Tab Materna - Tab Nutra-clear Vitaplex NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA B Totum 500 Liqui Infant Vitamins Magnum-75 Vitamin and Mineral Supplement Renate DHA Beminal 500 Tab Hi Potency Balanced B-100 Complex - Tab Fizz Multivitamins for Kids W C Loz Stress Ctr Srt Kids Stuff With Iron Tablets Multiple Vitamins 50 Plus Vimeral Tab Vitamin B-1 100 Mg Tablets Supravite Pour Enfants Duet DHA Balanced Vitamine 110 Liq Efferlife Multivitamins and Minerals Mvc M.V.I.-12 Enviroflex - Tab Thiamine HCl Tab 25mg Zyvit Prena1 Women's Formula Prenatal, DHA Great Day/am Formula Tab Multi-actin Children's Chewable Multivitamin Complete With Minerals Balanced B-complex Vit + Vit C&e Tab Vasculine PreNatal 19 Tricare Prenatal Flintstones W Extra C Tab Allbee C 800 Tab Mega-vim 75 With Beta-carotene - Tablets Mega Capsules Vigem 12 Liquid Vitranol Complexe B-75 Glyco Plus Ect MultiVitamin Drops with Fluoride and Iron Select OB Prenate Star One A Day Multiple Vit W Minerals Usana Megavitamin Tablets - Tab Mega 13 Multivitamin Formula Multi Vitamin - Mineral Kanga-kid Multi-vitamin & Mineral Neomultivite Vita Plex Tab OB Complete 400 Acti-thiamine Caplet 100mg Dialyvite 3000 Grand Master Formula Tab Stress B&c Tab Thiamiject Injection - Liq Im IV 100mg/ml Davimet Multiple Vit Plus Iron Tab Totalvit Plus Neo-vites & Minerals Tab Folika-V Cyroplex WesNatal DHA Complete Zintrexyl-C One A Day Advance Fem Poly-Vi-Flor Cedevita Sugar-free Vitamin Supplement Children's Chewable Multiple Vitamins - Tab Poly-Vite/Iron Oral Solution Childrens Chewable Multivitamins Premium Prenatal Daily Balance Tab Childrens Chewable Multiple Vitamins Tab Multi-11 B Complex W C Forte Cap Men's Twin Ultra Liquid Fruit Punch Flavor Edge OB Isotonix Multitech Vitamin Mineral Supplemen Folivane-Plus with Ascorbic Acid Precursors Liquid B Complex 50 Ply Vi Sol Chewable Tab Multi Vitamin Plus Iron Spectrum 2 Cap Vita Day Tab Vita B + C 500 Tab Multiple Vitamins With Iron Thiamine Hydrochloride Inj 100mg/ml Infuvite Adult Supravite Bouteille 250ml B Complex With C 550mg Nutra-Z RE Nata Stress Vitamin B With C Complex Tablets Rocky Mountain Multiple Vit and Min Mega Tab Deriton Extra Once A Day Women's Change Formula Moms Choice Rx Poly Vi Flor Chewable Tab Body Rox Neonatal19 Corvite Chewable Children's Complete Multivitamins With Essential Minerals Multivitamin Drops with Fluoride MultiVitamin with Fluoride Chewable L-Methyl PNV DHA Multivitamins for Children One A Day Advance Adults PNV Tabs 29-1 Lysamine Diet Supp Amp-tab Multi 1000 Neo-bex Injectable Balanced B50 Complex Nephrocaps-QT Se-Tan PLUS Childrens Chewable Multiple Vitamins W.iron Prenatal Plus Floravit - Syr Maximum Once A Day Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Multivit Et Fer Ampoules Et Comprimes Stress Formula Vit B With C Complex Dexatrim Tablets Twin Opti Pwr Biovita Cavan Folate OB Chewable Multiple Vitamins Tab Classic Swiss One 10 Multivitamin and Mineral Tab Envirocomplex Right Choice A.M. Multi Formula - Caplet Formula Gly Vitogen B Stress C600 Twin Ultra Liquid Lemon-lime Flavor Ultimate Tab Xvite Virt-Nate B Complex 500 Tab Hemarexin Liquid and Drinkable Ampoules Childrens Chewable Vitamins W Iron Stress B Capsules With Vitamin C Strovite Forte Caplet K.L. Vitamin-mineral Revit Plus Cap NephPlex Rx Balanced B-50 Complex Multi Spectrum - Tablet B-plus - Tab Balanced B-50 B-complex Vitamins, Timed Rele Prenatal Vitamin and Mineral Supplement Tab WesNate DHA Kanga-V Multivitamins & Minerals Children's Chewable Multivitamins and Minerals Centratex Children's Chewable Multivitamin and Multimineral M-Natal Plus Folet DHA Multi Vitamin and Fluoride Ellis Tonic B Complex Plus C 300mg Tab Chewable Multiple Vitamins Plus Extra C Gtf Support Caplet Polymine Avec Zinc Et Cuivre Quflora Pediatric Drops V-Natal Vitalife - Capsule Multiple Vitamins Plus Iron for Women Beminal Fortis Elx Children's Chewable Multi-vitamin Multiple Vitamins W Iron Tab Supravite Stress Avec Vit E Cuivre Et Zinc B-1 Caps 500mg Multi-vitamin Dietary Supplement Diaplex Multi-force for Adults Tab Croq-vit Pour Enfants Vitasure Phytopure Stress Tab With Zinc, Copper and Vitamin E New Chapter's D'adamo 4 Your Type Multiple for Type O Tender Age Multi Vitamins Vitamin B1 Tablets 100mg Hill.vite Men's Biomultiple Vitamin and Mineral Supplement Balanced B-100 Timed Release
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682