VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152 ?
Name	Thiamine
Groups	vet_approved nutraceutical investigational approved
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	thiaminium Aneurin thiamine(1+) thiamine(1+) ion Antiberiberi factor Thiamine hydrochloride Thiaminum Tiamina Thiamin Vitamin B1 Thiamine mononitrate Thiamine chloride Thiamine
Brand Names	Omega-3 Rx Complete Junior Multi Vitamins - Regular Gynedyn Tab PreQue 10 Protect Plus SO 60 Ventrixyl CitraNatal Assure Cavan Folate OB Children's Chewable Multi-vitamin B-complex With Vitamin C, Biotin, Folic Acid Efferlife Multivitamins and Minerals Vit B Complex Ctr B Complex Plus C 300mg Tab Childrens Chewable Multivitamins W Iron Croq-vit Pour Enfants NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vitamin B1 Vitramyn Cavan Folate DHA Vp-pnv-dha Relnate DHA N.E.U. Complex Multinate DHA B With C 500 Cap Children's Chewable Multiple Vitamins With Extra Vitamin C (chewable Tablets) Paramettes Adults Stress B Complex With C,e, Zinc and Copper Bugs Bunny Chew Multi Vit Plus Iron Venexa FE Pediatric Infuvite Multiple Vitamins WestGel DHA Magnum-75 Vitamin and Mineral Supplement Vigem 12 Liquid Neonatal DHA Multivitamins for Children Vitrexate Prenatal Vitamins Plus Children's Chewable Multi Vit W Iron Mega 13 Multivitamin Formula Chewable Adult Multivitamins With Minerals Replavite Swiss Total One Multi-Vitamin With Fluoride Virt-Bal DHA Plus Multi Vitamin Plus Iron Virt-Advance Xyzbac G Complexe B Compose 75 Biovita Trinatal GT Liqui Infant Vitamins Multivitamin with 0.25 mg Fluoride Vitamin and Mineral Supplement - Liq Vitaday Junior Tab Vitamin B Complex W C 300mg Tab Bewon Elixir 0.05mg/ml Focalgin CA Vita Vim Multivitamins and Minerals Tab Acti-thiamine Caplet 100mg B C Antistress Cap C-B Complex Maintain Multiple Vitamin & Minerals Allbee With Vitamin C Cap Multi Vitamin Drops with Fluoride with Iron Multivitamins and Minerals for Men Pregvit High Potency Vitamin B Complex + C Tab Mycelized Childrens Multi-vitamin Liq Kids Stuff With Iron Tablets Garfield Chewable Multivitamins Tab Revival 1 Tab Tricare Prenatal DHA One Vita-B-75 Cap Vitaflex Dietary Suplement Vitamin B-1 Thiamine HCl 100mg Master Key Multi Vitamin Multi Mineral Formula 2 Myhephron Dialysis and Stress Supplement Prenate Star Revit Multi-vitamins and Minerals Classic Swiss One 10 Multivitamin and Mineral Tab Only One - Tablet Vyo Cylate - Pwr PureVit DualFe Plus Inatal Advance TL-Care DHA Foliflex Prenate Elite PrePLUS PM Caps Bacmin DuetDHA Balanced Irospan 24/6 Kanga-B Vitamin B Group + C Multivitamins and Minerals - Complete Dexifol Virt Vite GT Obstetrix EC Stress Forte Plus Lipotropic Factors Multiple Vit Plus Iron Tab TL-Fluorivite Vitaplex Multiple Vitamins & Minerals Tablets Multi Vitamins & Minerals Vitabanks Vitamin Tab Right Choice A.M. Multi Formula - Caplet Vitafol One MI-Vite RX Folic-K Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Women's Formula Kanga-kid Vitamins & Iron B Totum 500 P.N.P. Vitamin Drink Stress Complex 600 Avec Vit E Cuivre Zinc Multivitamines Pour Enfants (chewable Tablets) Supravite Pour Enfants Vp-heme Ob DHA MultiVitamin, Iron and Fluoride Drops Complete Multivitamins and Minerals for Children Card-floe II Tab One Per Day Vitamin and Mineral Dietary Supplement Poly-Vitamin with Fluoride TM-Vite RX New Chapter's D'adamo 4 Your Type Multiple for Type O DuetDHA Complete Thiamine HCl Tab 50mg Grand Master Formula Tab Nutra-clear Stress B Capsules With Vitamin C MultiVitamin with Fluoride Drops B Complex With C 300mg Tab Escavite Lexazin Pnv-OB-dha Somarexin and C 1000 Vitafol Caplet Orange Flavored Crystal Chews Tab Nata Komplete Fusion Plus ahoSAN Acti-MN + B1 + C Caplet OB Complete Petite Formula B B 50 Capsules Twin Ultra Liquid Lemon-lime Flavor Mega-vim 75 With Beta-carotene - Tablets Multivit with Fluoride Glyco Plus Ect B-100 Caps Prenatvite Ultra Hr Poly-Vite/Iron Oral Solution Surbex-500 With Zinc Reno Caps PR Natal 430 ec Antlerviron Prim - Royal P.M.T. Chewable Multiple Vit Plus Iron for Children C. Vit-min Formula Natural Source Spectrum With Beta Carotene Iberet 500 Neonatal Vitamin Multi Rol Revit Plus Cap Essential Vitamins and Minerals Renate DHA Vitamines Pour Bebes Et Enfants Azesco RE Nata Virt-Nate B Complex Tablets Balanced B50 Complex Ventrixyl Fe NEONATAL Complete Surbex 500 Filmtab Daily Energy Brand B-complex HemeNatal OB plus DHA Vitamin B + C Cap B1 400mg Ctr Tab Active FE B Complex 50+ Caplet Chela-chromium 200 B Complex W Vitamin C Fortis Cap Kanga Sport Vitamins B & C Plus Minerals Phytofortis + Calcium A-D tensioSAN Balanced B-100 B-complex Vitamins Tab Formula F L W Multivitamin Drops with Fluoride Balanced B-50 B-complex Vitamins, Timed Rele Multi-Vit with Fluoride and Iron Multi Vitamin with Fluoride Vitamin B Tablets Alertonic Vitrexyl One Daily Vitamin and Mineral Dietary Supplement Vitamine Du Groupe B Plus Fer - Liq Multiple Vitamins Plus Iron for Women FloraFol Se-Tan PLUS Kenwood Liquid Supplement Vena-Bal DHA Livron Plus Ampoule Vitamin B-Complex VitaPhil Aide Hi Potency Multi Tab B Complex With C 550mg Nutrifer Plus Tablets Multi-vitamins Surbex-500 With Iron SetonET Kimchi Vitamin chewable multivitamin Infuvite Pediatric Orti B Multi Nt-OX Vol-Care Rx Poly Vi Flor Chewable Tab Folitin-Z B-complex Tab Bev B-150 Flintstones Multiple Vitamins Plus Iron Allbee C 800 Tab Megavites Tab Multicaps Men's Multi Master Formula Vitamine 110 Liq Multisol Ply Vi Sol Chewable Tab B50 B Complex Tab Phytoplex B Liq Bev 29 Tab Dialyvite 3000 Numark Multivitamins PNV-Select Geritol Liquid TriAdvance Materna Prenatol-M Liqui B Complex Plus Mega Vitaminerals Multiple Vitamin Plus Minerals Tab NovaMV Multivitamin Innersource Tab Animal Shapes w/Iron Chewtabs Mvc M.V.I. 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Stress Formula Multi-B Comp + 500mg Vit C Cap Duet DHA 400 50 Plus Multiple Vitamins & Minerals Dialyvite Multi-Vitamin Fluoride and Iron Drops Feminique W Iron and Calcium Tab Fizz Multivitamins for Kids W C Loz Liqui Vita NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Novel Vita Super Vitalex Ampoule Buvable Vasculine Stress Tab Livita Adults Vitogen B Stress C600 Body Rox Thiamine Hydrochloride NataFort Iron Polysaccharides Folic Acid DHA Children's Vitamins Chewable Permathene-12 - Caplet Nutri-Tab OB plus DHA Livita Children Natalvirt 90dha Vigo Multivitamins Drops/lozenge B-100 Complex Tablets Hemarexin Amp Enviroflex - Tab Multiple Vitamins With Iron Tablets NephPlex Rx Revitex Ampoules Et Comprimes Neonatal19 Men's 50+ Quflora Pediatric Drops Super Vita-vim With Beta-carotene - Tab PreGen DHA Pro Hers Vanilla Stress Formula Vitranol Fe Multi-Vitamin Drops with Fluoride and Iron H.W. Children's Chewable Multi Vit & Mineral Thiamine HCl Inj 100mg/ml Betaxin Liq 100mg/ml Vitamine B1 Tab 100mg USP Prenatal Supplement - Tab Venexa Dynam Ampoule Et Tablet Quflora FE Pediatric Drops Vitamin B1 Tab 100mg Choice OB DHA Flintstones Multiple Vitamins Women's Biomultiple Vitamin and Mineral Supplement Multi Vitamin Drops with Fluoride Materna-tab Vitafant Vitazyme Z Bec Tab Kaydia Patch Iron, Vit & Min Supp Synergistic Manganese Capsules Swiss One Multivitamin and Mineral Caplet Dexivite Everyday Multiple Vitamins Vita-amine Cap 100mg Zatean-Pn NataChew Multi Vitamin Drops with Fluoride and Iron Childrens Chewable Vitamins Mvc 9+4 Inj M.V.I.-12 Supravite Stress Avec Vit E Cuivre Et Zinc B Complex 500 Tab Poly-VI-sol Drops Kanga-kid Multi-vitamin & Mineral Hill.vite Viamon Ampoules Et Comprimes Prenatal Plus Vitamins Central-vite 18 Essential Stress B&c Tab Vita Vim With Beta Carotene-caplet Vitamin B Complex + C 300mg Cap Vitranol Ultra Enerforce Paramettes Syrup Zavitrol Kindervites Maxi 10 Tab Concept DHA PureFe Plus Wellness Formula Sopalamine/3b Plus C Multivitamins Vital Be-100 Pnv-VP-U TL-Folate Vit B Complex Plus Vit C 550mg Thiamine Hydrochloride Injection USP, 100mg/ml Children's Chewable Multi-vitamin Complete With Minerals B1 Tab 100mg Vitaphil 90 DHA WesCaps Paramettes Multivits Plus Iron Tab (teens) Daily Balance Tab Dialyvite with Zinc B-50 Complex Tab Prenatal Vitamins and Minerals Tablets Twin G.F. 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Vitamin and Mineral Drink Mix Vitamin B1 100 mg B6 Plus Tab B-Combo Floradix Formula Liq Multi Vite Liq Junior Prenatal Vitamins Plus Low Iron Enrich Core Pack - Children Vitamin and Mineral Supplement Multitabs Taron-C DHA Mega Balance Vitachrom Gc Multi Tabs Thiamine Hydrochloride Inj 100mg/ml USP Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Glyco Lite Ect Corvite Free Potassium Plus Vit B Complex Tendera-OB Thiamine HCl Tab 100mg Children Choice Multivit Chewable Tab Vita-worth B-complex Tablets Tricare Prenatal Compleat Multivitamins W Minerals Extra Strength Dermamed Nutrition for troubled skin Supravite 10ml Ampoule Formula Gm Formula Hh NESTABS Prenatal Multi-vitamin/Mineral Supplement Multi-Nate 30 Vitamines Et Mineraux Comprimes Gemvites Jr Tab Chewable Multi-actin Natal PNV NovaFerrum Multivitamin with Iron Pediatric Drops PreNatal 19 Multivitamins and Minerals for Young Women Gtf Support Caplet PureFe OB Plus Multi Vite Liq Adult B Complex 50 Vitamin Cap Keylosa Supravite Stress Avec Vit E Folika-NC Childrens Chewable Multiple Vitamins Zoo Chews Flintstones Multiple Vitamins Tab Escavite Lq Mvc 9 Plus 3 Inj Multiple Vitamins W Minerals Tab Vitamin B Compound W Vit C 250mg Tab B Virol Vitamines Et Mineraux Renate Vitafol Plus OB Complete Prenatal Pnv Ob DHA Distilpure Msm Luna Vitamin and Mineral Bar for Women Deriton Multivitamin & Minerals (iron Free) Dialyvite Supreme D Dothelle DHA Natavite Children's Chewable Multiple Vit.plus Iron CitraNatal 90 DHA Nephrocaps-QT Poly-Vi-Flor Maltlevol 12 Liq Timed Release B-complex 50 Triveen-Duo DHA Stress Formula B-comp + 500mg Vit C Tab Vitamin B Complex 50 Elite OB Prenatal Multivitamin Thrivite Rx PROTECT IRON Liquid Multi - N.T.O.x Formula - Tab Stress Formula Tab Gestamine Comprimes Dexatrim Tablets Am Caps Obstetrix DHA Combo Pack Prenatal Plus Iron Supplement De Multivitamines Infusion Arome Fruits Rouges Vitamin B1 Tab 2mg USP Multi-Vit-Flor Adult Infuvite Multiple Vitamins PNV Ferrous Fumarate Docusate Folic Acid Thiamiject Injection - Liq Im IV 100mg/ml TRONVite Davimet with Iron Diaplex Spectrum Performa Multivitamins and Minerals Tablets Omnivex Davimet with Fluoride Folivane-OB Duet DHA Hemarexin Liquid and Drinkable Ampoules Manganese 50mg Plus B1 & E Tab Stress B Complex With C and E Tab Stresstabs + Zinc-copper Vitamin B Compound W C Tab 500mg B-100 Hi Potency B Vitamins Tab Mebolic Multiple Vitamins and Minerals Tab Multiple Vitamins Plus Iron - Tab Marnatal F Folet DHA Vp-heme Ob Opti-manganese + B1 + C Caplet Prenatal Formula Tab Thiamine HCl Injection - Liq 100mg/ml Complexe B-75 Poly-Vite Pediatric Oral Solution RE Prenatal Multivitamin with Iron WesCap-C-DHA Multi Plex I - Tab Extra P.N. Vitamin-mineral Drink Mix THIAMINE HYDROCHLORIDE injection, solution Virt-PN Balanced B100 Childrens Chew Multi Vitamin Tab Stress Tablets Davimet Formula Fm Vitamins & Minerals Tab Twin Opti Pwr Vitogen B Stress C Vit E Zinc & Cop Insur-all Vitamin Supplement Childrens Chewable Multivitamins T.R.I. B-plex Src Vitamin B Complex B Plus C 300 mg MVC-Fluoride Daily-Vite Niva-Plus Penta-thion Pwr Chela-manganese 50 Plus Virt-Nate DHA Chewable Multiple Vitamins for Children RayaVit Nitro Vites - Tab Maltlevol Liq B Vitamin Compound With B12 Thunas Multi Vitamin, Iron and Fluoride Folika-V Multi Plex II - Tab Virt-Vite Plus Vege Swiss One Multivitamin W Chel Mins Tab Virt-Pn Senior Multi One Jenliva Prenatabs FA Vita Day Tab Vitasure Vitaday Tab Multitam Beminal With C Fortis Pws For Kids Only Chewable Multivitamins - Tab Palm Springs Multvit and Min Tab Multivit Et Fer Ampoules Et Comprimes Edge OB Ultimate Tab VIL-Rx B50 Complex Childrens Chewable Multiple Vitamins W.iron Chela Iron Plus C,b Complex Multi Vitamin-mineral Formula Osteo-force Lipo-B-C Tab Multi-Vit with Fluoride Betaxin Thiamine Hydrochloride Injection, USP Virt-Caps vitaMedMD Rx Plus B-complex 50 Stress B Complex With C, E and Iron Tab Vitrexate FE Balanced B 125 Srt Dalivit Balanced B-100 Timed Release Hyporyl - Tab Bugs Bunny and Friends Multiple Vitamins B-complex 100 Strovite One Caplets Chela Potassium Plus Cyroplex Flintstones W Extra C Tab Vita-Pac Folivane-Plus with Ascorbic Acid Precursors Multi Enfants Tab Multivitamins and Minerals for Young Men Children's Vitamins W Iron Chewable Multi B PNV Tabs 29-1 Hi Potency Balanced B-100 Complex - Tab Fortistress Tab Mini-B Tab Multi-vitamins With Minerals One A Day Advance Adults Twin G.F. Powder Vanilla Flavor Finazol Complete Multivitamins and Minerals Tablets Timed Release FolaGent DHA Phytopure Multi-Vitamin with Fluoride Lorid Children's Chewable Multivitamin and Multimineral Advanced B & T Formula Chewable Children's Complete Multivitamins With Essential Minerals Children's Chewable Vit and Min Tab Timed Release B-complex 100 Preplus Vita B + C 500 Tab Vitamin B Complex Tab Ferra Naka Plus Vitamins Prenara B Compound 50mg Tab Oncovite Timed Release B Complex 100 Srt Hi Potency B Complex W Chelated Minerals Nutri-Tab OB One A Day Tab Multivitamins and Minerals With Betacarotene Tablets Multivitamin with fluoride Chewable Multivitamins Plus Iron CitraNatal DHA M-Natal Plus RE FAC-x Thrivite 19 Synergistic Manganese Cap CompleteNate Chewable Chew.multiple Vits.with Extra C for Children Vita-vim - Tab Glyco-aide Tab Tender Age Multi Vitamins Fortamines 10 Capsules Stress Formula Vit B With C Complex Complex 5 - Pwr Mangadyn G.A.S. 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Adult Mor-vites Tab Children's Chewable Multiple Vitamins With Iron Tablets (chewable Tablets) Vimeral Tab Formula Pro-B Cc II Nephron FA RenaPlex-D Stress B & C Caplet Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Poly-VI-flor Multivitamins and Minerals Tablets THIAMINE HCl Prometa Time Release B 100 Compound - Tablet Flinstones Multiple Plus Iron Complete Mega B Thiamine HCL 100 mg Neonatal Plus Vitamin Chewable Multivitamins Folika-T Vc II Multi-Vitamin Fluoride Drops Premium Prenatal Materna - Tab Multi #2 Sibergin B - Cap Ribotin-E B-100 Vitamin Supplement Super Charged Energy Virt-C DHA B Complex With C 300mg DaVITE For Kids Only Chewable Multivitamins D'pantothenic Acid-B1-B2 Tab Mega Capsules Multivitamin & Multimineral Paire OB Plus DHA Pregnancy Multivitamin Multiple Vitamins W Iron Tab Sopalamine/3b Tab Stress Formula + Iron Multi Vitamin - Mineral Multi Pro Ultimate OB DHA Cedevita Sugar-free Vitamin Supplement Multi 1000 Infa Drops Multivitamins Multra Plex Century Complete Hemarexin Tab B Complex W C Forte Cap Vitafol Ultra Se-Natal 19 B Plus C 300mg Timed Release B-plex 100 Se-Care Conceive For-2 Vitamine B1 100 Mg - Tablet B-plex Multiple Vitamins Childrens Chewable Vitamin & Mineral Formula 1 Dietary Supplement Vtb Vitamin and Mineral Supplement Children's Chewable Multiple Vitamins (chewable Tablets) Orifer F Vitaphil DHA Floriva Vitrexyl plus Iron Childrens Multiple Vit and Min Chew Tab Maxi 6 Liq Vitafer - Liq C.R.T. X Multivitamin & Mineral Powder Mix Corvite Nutra Boost C-force B-50 Complex Beminal Fortis Elx Children's Chewable Tab Essential B Tablets Hylazinc Formula Gly Multivitamine One A Day Multiple Vit W Minerals Iron Folate Plus Provida OB Total Living Concepts Formula One - Tab Vitamin B1 100mg INATAL Ultra Prevital Tab Appedrine Bewon Elixir PNV Prenatal Vitamin Plus Vitamin A Vitamin B1 100mg Tablet Folica BE Prenatal Plus Multivitamin Plus DHA MiniCaps Concept OB Childrens Chewable Multiple Vitamins Plus Fe Multi-force for Adults Tab Se-Natal Mega Plex III - Pck Hemocyte Plus Prenatryl Vitamin B Complex Plus 300mg Vitamin C Thiamine Hydrochloride Inj 100mg/ml Provida DHA MultiVitamin with Fluoride Omniquin Timed Release Vita-vim Srt Stress B With 1000 Mg Vitamin C Nephrocaps Trinaz Se-Natal 19 Chewable OB Complete 400 vitaMedMD One Rx Multi-phyto Capsules Totalvit Plus Children's Chewable Multi Vitamins With Iron Tablets Revit Tab Twin Ultra Liquid Grape Flavor Childrens Chewable Vitamins W Iron Corvita M.V.I. Paediatric Dia-vite Children's Chewable Multivitamins With Minerals Multi-kid Neomultivite Adeks Tablets Select OB Childrens Chewab Vitamin W Chel Minerals P.R.O. Complex RE Nata OB E.S.T. Complex OB Complete DHA Stress Vitamin B With C Complex Tablets Natal-V RX Multi-vitamin/Multi-mineral Low Potency B Complex Tab Vita-B Cavan-EC SOD DHA Stress Tab With Zinc, Copper and Vitamin E Cedevita Plus Vitamin Supplement Derma-force Multivitamins and Minerals for Women Strovite Forte Caplet Complete-RF Prenatal Men's Biomultiple Vitamin and Mineral Supplement Tricare Prenatal Quick Dissolve WesNatal DHA Complete Super Daily No 2 PR Natal 400 PreferaOB plus DHA Tricare Prenatal Trinatal Rx 1 Super Stress Capsules PNV Prenatal Plus Multivitamin Vasula Tab C-Nate DHA Mega Plex IV - Pck Cavan Prenatal Chewable Multiple Vitamins Tab Multivitamins and Multiminerals Formula Regular Tablet Dialyvite 5000 Multi Vitamines - Liq Dayavite Multivitamines Plus Fer Pour Enfants (chewable Tablets) Virt-Tabs Vol-Tab Rx Phosthenine Vitamines Et Fer (ampoules Buvable) Maximum Once A Day Multiple Vitamins - Tablet P.N. Vitamin-mineral Drink Amladex Vital-D Rx V-Natal Fem Time Tab Genicin Vita-Q Balanced B-50 B-complex Vitamins Tab Multivitamines Supravite Stress Avec Vit E Et Fer Vinate AZ Zoo Chews Plus Iron Folica-V Children's Chewable Multivitamin Complete With Minerals Davimet-M SetonET-EC Swical-energy 3e Age VitaXyme Vitamines Et Mineraux Enfants 970 Maxine Vitamin and Mineral Supplement Super Vita Vim Multivitamins and Minerals Liqui B Complex B-plus - Tab Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals One Daily VITES Vitamin B Compound Tab Multi-vitamines Enfants Comprime Multipack II Women's Change Formula Complete One A Day Tab Beminal W C Fortis Inj Poly-Vi-Flor with Iron Vitamin B-1 100 Mg Tablets Multivitamin with 1.0 mg Fluoride Vyqua HemeNatal OB Foltabs Prenatal Plus DHA Children's Chew Multi & Min Tab Chewable Multiple Vitamins Plus Extra C Lipotropic Ctr Floravit - Syr Multivitamins W Iron Prenatal, DHA Extra Once A Day Spark Cap Prena1 Nutrol-B-complex Renal Caps Dialysis/Stress Vitamin Supplement High Potency Multivitamins & Minerals Caplets PreNatal Vitamins Plus Re Ob 90 DHA Neo-vites & Minerals Tab Duet DHA 400 ec Olympian Multi Vit Plus Minerals Tab Multi-Vitamin Prenatal Vi-min Liquid B Complex 50 Everyday Multiple Vitamins With Iron Neo Bex Elixir Thiamine HCl Tab 25mg Vege 1 Daily Tab Medi Msm (methyl Sulfonyl Methane) Vita Plex Tab Vitafol Fe Plus Vitalife - Capsule PR Natal 400 ec Thiamine Biovim Tab Lipovite Natalvirt Ca Chromease Tab Twin Ultra Liquid Orange Flavor NeuroBion Multi-12 Pediatric Harvest Of Values All B Complex Tab Multi-12/k1 Pediatric
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682