VIB

3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM

Created:	2001-04-17
Last modified:	2020-01-26

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Chemical Details
Formal Charge	1
Atom Count	35
Chiral Atom Count	0
Bond Count	36
Aromatic Bond Count	11

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Chemical Component Summary
Name	3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
Synonyms	THIAMIN; VITAMIN B1
Systematic Name (OpenEye OEToolkits)	2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
Formula	C₁₂ H₁₇ N₄ O S
Molecular Weight	265.355
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	n1c(c(cnc1C)C[n+]2c(c(sc2)CCO)C)N
SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
Canonical SMILES	CACTVS	3.341	Cc1ncc(C[n+]2csc(CCO)c2C)c(N)n1
Canonical SMILES	OpenEye OEToolkits	1.5.0	Cc1c(sc[n+]1Cc2cnc(nc2N)C)CCO
InChI	InChI	1.03	InChI=1S/C12H17N4OS/c1-8-11(3-4-17)18-7-16(8)6-10-5-14-9(2)15-12(10)13/h5,7,17H,3-4,6H2,1-2H3,(H2,13,14,15)/q+1
InChIKey	InChI	1.03	JZRWCGZRTZMZEH-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB00152 ?
Name	Thiamine
Groups	nutraceutical investigational approved vet_approved
Description	Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.
Synonyms	Aneurin Thiamine mononitrate Tiamina Thiamine chloride Thiamine Thiaminum thiamine(1+) ion thiamine(1+) Vitamin B1 Antiberiberi factor thiaminium Thiamin Thiamine hydrochloride
Brand Names	Jenliva NataFort Hyporyl - Tab Prenatal Vitamin and Mineral Supplement -tab Vitaplex Feminique W Iron and Calcium Tab Vitamine B1 100 Mg - Tablet Glyco-aide Tab Puralor Kid's Choice Children's Chewable Vitamins - Tab Sopalamine 3b Plus Stress Tab With Zinc, Copper and Vitamin E tensioSAN Stress B-complex Plus Iron With Vitamins C&e Cal M Tab Vitamin B1 100 mg Duet DHA Balanced Orifer F Chewable Multivitamins Twin G.F. Powder Folika-V PureFe Plus Balanced B-100 B-complex Vitamins Tab Genicin Vita-S Kanga-kid Multi-vitamin & Mineral Dynam Ampoule Et Tablet B Stress C + Iron & Vite Ferra Naka Plus Vitamins PR Natal 430 Se-Care Conceive Multra With Iron Triveen-Duo DHA Children's Chewable Multi Vitamins With Iron Tablets Finazol Kimchi Vitamin chewable multivitamin Multivitamin & Minerals (iron Free) For Kids Only Chewable Multivit. Plus Iron Florafol FE Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops TL-Fluorivite Timed Release B-complex 50 Multi Rol Women's Biomultiple Vitamin and Mineral Supplement OBTREX DHA Combo Pack Bewon Elixir 0.05mg/ml Prenatal Vitamins Plus Twin Ultra Liquid Grape Flavor Sopalamine/3b Plus C Mega-vim 75 With Beta-carotene - Tablets Vitrexyl Infuvite Pediatric Thiamine Multi-12 Pediatric Vp-heme Ob Prenatrix Stress Formula Vit B With C Complex Allbee With Vitamin C Cap Vitamin B-1 100 Mg Tablets Corvita Super Stress Mega B Plus 1000mg Vit C Tab NEONATAL Complete Fem Time Tab Formula O.C. Davimet-M Derma-force Mangadyn Multiple Vitamins and Minerals RenaPlex Corvite Free Prenatal Vitamin and Mineral Supplement Tab Thiamine HCl 100mg W C 20mg HemeNatal OB Pro Hers Vanilla Chewable Multiple Vitamins Plus Extra C Quflora FE PR Natal 400 ec Multivitamin & Multimineral Gesticare DHA Deriton CitraNatal Rx E.S.T. Complex Vitamin B1 100mg Tablet Super Pantoplex TL-Folate C-Nate DHA Innersource Tab TM-Vite RX B Complex 25mg Vitamin Supplement Complete Natal DHA Multivitamins and Multiminerals Formula Regular Tablet Alsimine W Vitamins A D Kids Stuff Tablets B Complex With C 300mg B 50 Capsules Prenatal and Post Partum Supplement Prenatvite Complete VIL-Rx Biovim Tab Virt-Pn Palm Springs Multvit and Min Tab Permathene-12 - Caplet Men's Multi Master Formula Onccor Multivitamin Multi Vitamin & Minerals B-plus - Tab Vitafant Children's Vitamins Chewable Myhephron Dialysis and Stress Supplement Complex-75 Timed Release Vita-vim Srt Nutrol-B-complex Foltabs Prenatal Mor-vites Tab Complete Mega B Folivane-OB Hi Potency B52 B Complex Tab Multivitamins New Chapter's D'adamo 4 Your Type Multiple for Type O Phytovim Cap Swical-energy-2 Paramettes Chewable Multivitamins Plus Iron Virt-Tabs Floradix Formula Liq Vita Balance 2000 TriphroCaps Central-vite 18 Essential Vitabanks Vitamin Tab HemeNatal OB plus DHA Niva-Plus B-complex Tab PreGen DHA Relnate DHA Supravite Stress Avec Vit E Cuivre Et Zinc Vita Vim Multivitamins and Minerals Tab Vol-Nate Senior Multi One WesCaps One A Day Tab Vitamin B Complex W C 300mg Tab Harvest Of Values All B Complex Tab Vitamin B Complex Plus C 300mg Timed Release Multipack II Vitamin B Complex Suppl One Daily VITES Provida DHA One A Day Advance Adults Iron, Vit & Min Supp Cavan-EC SOD DHA DaVITE Revit Plus Cap Stress Tab PNV Prenatal Vitamin Plus Vitamin A Cavan Heme OB T.R.I. B-plex Src Gestamine Comprimes Leritone Junior Nutra Boost Xyzbac G B Plus C 300mg Timed Release Beminal 500 Tab Virt-Nate Vitafol OB Caplet Mebolic B Vitamin Compound With B12 Thunas Multi II IV Vi Tab Multivitamines Pour Enfants (chewable Tablets) B1 400mg Ctr Tab Thiamine HCl Inj 100mg/ml bioJET L.G.I.T. Hemarexin Liquid and Drinkable Ampoules Liqui Infant Vitamins OB Complete 400 Stress B Complex With C,e, Zinc and Copper Paramettes Chewable Multivits With Iron Tab Multivitamines Et Mineraux Daily Balance Tab Prenatvite Plus Vitaflex Dietary Suplement High Potency Vitamin B Complex + C Tab Mini-B Tab Escavite Lq Multi-Vit with Fluoride and Iron Vitranol Vol-Care Rx Vtb Vitamin and Mineral Supplement Nutra-Z Potassium Plus Vit B Complex Formula Lf Choice OB DHA Multi-Vitamin Fluoride Drops One A Day Advance Fem WesCap-C-DHA Children's Chewable Multivitamins and Minerals B1 Tab 100mg Milltrium Senior Vitamin and Mineral Supplement Vita Plex Tab Chewable Multivitamins Plus Iron Natalvirt 90dha Vit-HA Multi Vitamin and Zinc Supplement Vitazyme Nata Komplete Stress Tablets Marnatal F Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Liqui B Complex Vigo Multivitamins Drops/lozenge Multi-Vitamin With Fluoride Active FE Stressmates Vp-pnv-dha PreNatal 19 Children's Chewable Multivitamin Complete With Minerals Multi 1000 Twin Ultra Liquid Fruit Punch Flavor Vitamin B Complex + C 600mg Tab Chela-manganese 50 Plus Childrens Chewable Vitamin Tab Materna PrePLUS MultiVitamin with Fluoride Chewable Vitamin B-1 Thiamine HCl 100mg Vitamin B1 Tab 100mg Balanced B-100 Timed Release Amladex Supravite Stress Avec Vit E Zoo Chews Lysamine Diet Supp Amp-tab Isotonix Multitech Vitamin Mineral Supplemen MI-Vite RX PROTECT IRON Liquid Vita-Rx Diabetic Vitamin Zoo Chews Plus Iron Complexe B Compose 75 Extra Once A Day Prenatal Vitamins and Minerals Tablets For Kids Only Chewable Multivitamins Zalvit B Compound 50mg Tab Gemvites Jr Tab Chewable RE Prenatal Multivitamin with Iron Distilpure Msm Bacmin Liqui Vita Duet DHA 400 ec Preplus Kids Stuff With Iron Tablets Vinacal B Complex With C 300mg Tab Childrens Chewable Tab Foliflex Hylazinc Tricare Prenatal DHA One Trinatal Ultra Vitamines Et Mineraux Comprimes Prenatal Insur-all Vitamin Supplement Ultra Enerforce B Complex W Vitamin C Fortis Cap Prenatal Formula Tab Vitamin B1 TL-Care DHA Genicin Vita-Q Nephron FA Formula B Tender Age Multi Vitamins Vitalife - Capsule Reno Caps Vitaphil DHA Ply Vi Sol Chewable Tab Usana Megavitamin Tablets - Tab Dexivite Natal PNV Multi-Vit with Fluoride Dexifol Supravite Bouteille 250ml Totalvit Plus Biovita Somarexin and C 1000 Multivit-liq Cyroplex Provida OB Thiamine HCl Tab 50mg Fortamines 10 Capsules Vital-D Rx Card-floe II Tab Kanga Sport Vitamins B & C Plus Minerals M.V.I. Pediatric Maxine Vitamin and Mineral Supplement Multi Plex II - Tab Vitamine 110 Liq Nutrilite Double X Neomultivite Multi Vitamins & Minerals Davimet with Iron Hi Potency Multi Tab MYNEPHROCAPS DIALYSIS/STRESS Vitamin Supplement Right Choice A.M. Multi Formula - Caplet Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vitafol One Chela-chromium 200 Stress Ctr Srt Megavite Rx Extra P.N. Vitamin-mineral Drink Mix Childrens Chewable Vitamins Multi Nt-OX Nitro Vites - Tab Children's Chewable Multi Vitamins Multi Vitamin-mineral Formula Se-Plete DHA Hi Potency B Complex W Chelated Minerals Vitamin B Complex W C Tab RayaVit Revitalize Multi-vitamin and Mineral Complex Stress B & C Caplet Prenate Star Formula Hh Children's Chewable Multi-vitamin Complete With Minerals Prenate Elite Venexa B-1 Caps 500mg Bal-Care DHA Nephrocaps Vimeral Tab Poly-Vi-Flor with Iron Multiple Vitamins Plus Iron - Tab Daily Energy Brand B-complex Foltabs Prenatal Plus DHA Croq-vit Pour Enfants Methaver Chela Iron Plus C,b Complex Inatal Advance Cavan Alpha Chewable Multiple Vitamins for Children Se-Natal 19 Surbex 500 Filmtab Children's Vitamins W Iron Chewable Natal-V RX Multi-vitamin/Multi-mineral Floriva Plus Childrens Multiple Vit and Min Chew Tab Multiple Vitamins With Iron Tablets Bal-Care DHA Essential Multra Plex Multivitamins and Minerals for Young Men PNV Prenatal Vitamin Vitafol Caplet Florafol Pediatric 0.25 mg/mL Multivitamin and Fluoride Liquid Drops Hylavite MVC-Fluoride Super Vita-vim With Beta-carotene - Tab Bewon Elixir OB Complete DHA Kanga-kid Vitamins & Iron NataChew RE Nata Swiss One Multi Vit & Chel Min Tab M.V.I.-12 Maltlevol Liq Vasula Tab Ventrixyl Vita-vim With Beta-carotene - Tab Prena1 Plus Stress Tab With Iron and Vitamin E Dermamed Nutrition for troubled skin Neonatal Vitamin Focalgin 90 DHA Multiple Vitamins Plus Iron for Women Multivitamins W Iron PureVit DualFe Plus OB Complete Prenatal Spectrum Performa Multivitamins and Minerals Tablets B Complex 500 Tab Virt-Caps Premium Prenatal Balanced B100 NovaMV Multivitamin Se-Tan PLUS P.R.O. Complex Timed Release B Complex 100 Srt Mega Plex III - Pck Nutrifer Plus Tablets Prenatol-M Stresstabs + Zinc-copper Liqui B Complex Plus Escavite Paire OB Plus DHA Thrivite 19 Women's Change Formula B Complex 50 Vitamin Cap Children's Chewable With Iron G.A.S. Complex Stress B Complex With C, E & Iron Alkadrenergy Tablets Tini-cal Ampoules Fusion Plus Super Vitalex Ampoule Buvable Men's Twin G.F. Powder Vanilla Flavor B With C 500 Cap Super Daily No 2 Tricare Prenatal Quick Dissolve One-A-day Advance Men's Concept OB Balanced B-50 B-complex Vitamins, Timed Rele Animal Shapes w/Iron Chewtabs Junior Multi Vitamins - Regular Betaxin Magnum-75 Vitamin and Mineral Supplement Vita-worth B-complex Tablets Quflora Pediatric Drops Neo Bex Elixir Childrens Chewable Vitamins W Iron Vitogen B Stress C Vit E Zinc & Cop One A Day Advance Adults 50+ Women's Formula Adult Formula 50+ B C Antistress Cap Children's Chewable Multiple Vit.plus Iron Hemarexin Amp Children's Chewable Multiple Vitamins - Tab Complete One A Day Tab Dalivit Prenatryl Super-pote Vitamin Supplement Children's Multivitamins Childrens Chewable Multivitamins W Iron Revitex Ampoules Et Comprimes THIAMINE HYDROCHLORIDE injection, solution Concept DHA Fortamines-10 Comprimes vitaMedMD One Rx Vitamin B Compound W Vit C 250mg Tab Tandem OB MultiVitamin with Fluoride B-plex AzesChew Keylosa Multiple Vitamins and Minerals Capsules Flintstones W Extra C Tab Livron Plus Tab Infuvite Adult Folivane-Plus with Ascorbic Acid Precursors Vitrexate Poly-Vite Pediatric Oral Solution Diaplex Childrens Chewable Multiple Vitamins Tab Vasodyn Tab Chewable Multiple Vitamins Plus Iron Tab Pregvit Folic 5 Multi-vitamins With Minerals Polymine Avec Zinc Et Cuivre Animal Shapes Se-Natal 19 Chewable Everyday Multiple Vitamins With Iron Vita-amine Cap 100mg L-Methyl PNV DHA Balanced B-50 Complex O-Cal FA multivitamin Multi Vitamin Drops with Fluoride and Iron B-50 Complex Tab Multi B Vitamin B Complex 100 Tab Multiple Vitamins Zeldana Cavan Folate DHA hormaSAN forte Neo-bex TriStart DHA Protect Plus SO 60 vitaMedMD Rx Plus Cavan Folate OB H.W. Children's Chewable Multi Vit & Mineral Poly-Vitamin with Fluoride Multivitamines Et Mineraux Junior Regulier Multi-vitamines Enfants Comprime Toni Com Liq Vita Day Tab Formula F L W Dothelle DHA High Potency Multivitamins & Minerals Caplets Obstetrix DHA Combo Pack Vege 1 Daily Tab Lipo-B-C Tab Materna - Tab Neo-vites & Minerals Tab Vc II Strovite Forte Caplet Vol-Plus One A Day Multiple Vit W Minerals Vitamin B Complex 100 Body Rox Multi Spectrum - Tablet Timed Release B-complex 100 Xvite CompleteNate Chewable Garfield Chewable Multivitamins Tab Zintrexyl-C B Complex Plus C 300mg Tab Pregvit One-A-day Advance Fem - Tablets Sibergin B - Cap Children's Chewable Multivitamin and Multimineral Thiamine Hydrochloride Inj 100mg/ml USP Edge OB Iron Folate Plus Tricare Prenatal DHA One Rx Multivitamin Complete One-A-day - Tab Multiple Vitamin Plus Minerals Tab Cc II B 6 Plus Chewable Children's Complete Multivitamins With Essential Minerals Mega 13 Multivitamin Formula Beminal With C Fortis Pws Childrens Chewable Multiple Vitamins Plus Fe Balanced B-complex Vit + Vit C&e Tab Chewable Adult Multivitamins With Minerals Gtf Support Caplet B Complex With C 550mg Neonatal Plus Vitamin M.V.I. 12 B-100 Hi Potency B Vitamins Tab B-complex Tablets Men's Biomultiple Vitamin and Mineral Supplement Low Potency B Complex Tab Viamon Ampoules Et Comprimes OB Complete Petite Nephrocaps-QT Multivitamins for Children Renate Multi Flow Tablets Multi-Vitamin Fluoride NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Phytofortis + Calcium A-D Kenwood Liquid Supplement N.E.U. Complex Pregnancy Multivitamin Maxi 10 Tab B-50 Complex Super Stress Capsules Ribotin-E Childrens Chew Multi Vitamin Tab Multivitamin with 0.25 mg Fluoride Phosthenine Vitamines Et Fer (ampoules Buvable) MultiVitamin Drops with Fluoride and Iron Multiple Vitamins W Iron Tab Prenatal Vi-min PreTAB Balanced B50 Complex Multiple Vitamins and Minerals Tab Vyo Cylate - Pwr Renal Caps Dialysis/Stress Vitamin Supplement Bugs Bunny Chew Multi Vit Plus Iron Fortistress Tab Multicaps Thiamine Hydrochloride Injection USP, 100mg/ml Infa Drops Multivitamins Vp-heme Ob DHA WestGel DHA VitaPhil Aide Children's Chewable Vit and Min Tab Maintain Multiple Vitamin & Minerals PM Caps Rocky Mountain Multiple Vit and Min Mega Tab Neonatal DHA Se-Natal Vitramyn Stress Formula Glyco Plus Ect Pnv-VP-U Dexatran Formula Pro-B Q.T. 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Vit-min Formula PNV-First Virt-Advance Hormodausse Plus Calc Et D Tab Spark Cap Multi-kid Multivitamines Plus Fer Pour Enfants (chewable Tablets) Ziphex Virt-Vite Plus Livron Plus Ampoule Swical-energy 3e Age Vitamin B Compound Tab SetonET Alertonic CitraNatal Assure Gynedyn Tab Duet DHA 400 M.V.I. Adult Moms Choice Rx Total Living Concepts Formula One - Tab Zavitrol Vena-Bal DHA PNV Prenatal Plus Multivitamin Prenatabs FA Chewable Multiple Vit Plus Iron for Children Neo Vites Tab Surbex-500 With Iron Pediatric Infuvite Multiple Vitamins Prenara PreferaOB plus DHA Multivitamines Et Mineraux Reguliers / Regular Multivitamins and Minerals Vitamin B-Complex Thiamine HCl Injection - Liq 100mg/ml Vasculine B Complex Tablets B-complex 50 Flinstones Multiple Plus Iron Flintstones Multiple Vitamins Multi Pro ahoSAN Lorid P.N.P. 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Paediatric Prefera OB plus DHA Forty Plus Vitamin Supplement Doctor's Choice Brand for Men Trinatal GT Vege Swiss One Multivitamin W Chel Mins Tab DuetDHA Complete Balanced B-50 B-complex Vitamins Tab MultiVitamin, Iron and Fluoride Drops Dia-vite Numark Multivitamins Folic-K One Daily Vitamin and Mineral Dietary Supplement PreferaOB Prevital Tab Mvc 9+4 Inj Meplex T 750 B-100 Vitamin Supplement D'pantothenic Acid-B1-B2 Tab Only One - Tablet B-plex 100 B-complex-50 Tab Acti-thiamine Caplet 100mg PureFe OB Plus Multi-12/k1 Pediatric Hemocyte Plus PR Natal 430 ec Multivitamin Drops with Fluoride Natavite Swiss One Multivitamin and Mineral Caplet Trinatal Rx 1 Prena1 Complexe B-75 Iberet 500 Omnivex Maxi 6 Liq Ultimate OB DHA Thiamine HCL 100 mg 50 Plus Multiple Vitamins & Minerals WesNatal DHA Complete Neonatal19 Prometa Se-Natal One PNV-Select Multi-Nate 30 Cedevita Sugar-free Vitamin Supplement Prim - Royal P.M.T. RE Nata OB Revival 1 Tab Venexa FE Children Choice Multivit Chewable Tab Trinaz Allbee With C 550 Cap Childrens Chewable Multiple Vitamins Multi-actin Sun-rype Vitaburst Vitafer - Liq B-100 Caps Elite OB Prenatal Multivitamin Multi-Vitamin Drops with Fluoride and Iron B-100 Complex Tablets CitraNatal Essence Multivitamins and Minerals Tablets Formula Gm Prenatal Vitamins Plus Low Iron Vitamin B Tablets Multinate DHA Folitin-Z Vitafol Plus Wellness Formula Children's Chewable Multivitamins With Minerals Multiple Vit Plus Iron Tab Vitogen B Stress C600 Lipotropic Ctr B Complex 50+ Caplet Formula Gly Multisol Oncovite Pretrate Vitaday Junior Tab NESTABS ABC Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Neo-bex Injectable Children's Chewable Multiple Vitamins (chewable Tablets) Kindervites Supravite Stress Avec Vit E Et Fer VitaXyme Dialyvite Folika-NC Prenatal Plus Prenatvite Multivitamin with 1.0 mg Fluoride B-complex With Vitamin C, Biotin, Folic Acid Time Release B 100 Compound - Tablet Multiple Vitamins & Minerals Tablets SetonET-EC Mvc Great Day/am Formula Tab B Virol 50 Plus Multiple Vitamins With Iron Dialyvite 3000 Stress Formula Multivitamin Tablets USP Ventrixyl Fe Nutri-Tab OB plus DHA Integra Plus Medi Msm (methyl Sulfonyl Methane) NESTABS Prenatal Multi-vitamin/Mineral Supplement Novel Vita Am Caps Azesco Obstetrix EC Paramettes Syrup Folika-T Vitamine Du Groupe B Plus Fer - Liq Century Complete Select-OB Plus DHA Prenatal Supplement Plus DHA Advanced B & T Formula Cda-21 Vitamins With Non-medicinal Probiotic Complex Multi-11 Men's 50+ Multivitamin with fluoride Opti-manganese + B1 + C Caplet Multi-Vitamin with Fluoride Stress Formula + Iron Super B Compound W 500mg Vit C TriAdvance Dexatrim Tablets Tendera-OB Multi Enfants Tab K.L. Vitamin-mineral Thiamine HCl Tab 25mg Soluvit N Fibrik Children Choice Multivitamin W Iron Chew Tab Centratex Tonicol Et A-D-C Ampoules/comprimes Chromease Tab Chela Potassium Plus FolaGent DHA INATAL Ultra MultiVitamin with Fluoride Drops Multivitamines B-Combo Phytopure Virt-Bal DHA Plus FloraFol Stress Vitamin B With C Complex Tablets Spectrum 2 Cap Orange Flavored Crystal Chews Tab Revit Tab Poly-Vite/Iron Oral Solution For Kids Only Chewable Multivitamins - Tab Enviroflex - Tab Efferlife Multivitamins and Minerals Vitamines Pour Bebes Et Enfants Thiamiject Injection - Liq Im IV 100mg/ml Re Ob 90 DHA Nrg Plus Liq Ellis Tonic Active OB Multivitamins and Minerals With Betacarotene Tablets Omniquin Mega Vitaminerals Virt-C DHA Vitaphil 90 DHA healthy mamaBE WELL ROUNDED BE WELL ROUNDED Multitabs Sopalamine/3b Tab Manganese 50mg Plus B1 & E Tab Super Vita Vim Multivitamins and Minerals Orti B Super Charged Energy Acti-MN + B1 + C Caplet L.C. Supplement Vitranol Fe Childrens Chewable Multiple Vitamins W.iron Vitamin B1 100mg Vitamin B Compound W C Tab 500mg Multiple Vitamins W Minerals Tab Thrivite Rx Vitafol Fe Plus Multi-vitamin Dietary Supplement Olympian Multi Vit Plus Minerals Tab Z Bec Tab Swiss One Vitachrom Gc Multi-force for Women Tab Ultimate Tab Zyvit For-2 Chew.multiple Vits.with Extra C for Children Maltlevol 12 Liq Swiss One Timed Release Tab Adeks Tablets Stress B Complex With C, E and Iron Tab Everyday Multiple Vitamins Iron 25mg With Vit B-cmplx, Vit C, Cu & Mo Irospan 24/6 Multiple Vitamins Plus Iron Tab Complete Multivitamins and Minerals Tablets Timed Release Prenatal, DHA Strovite One Caplets Vitamin B Complex O-Cal Prenatal Vitamin Luna Vitamin and Mineral Bar for Women Omega-3 Rx Complete P.N. Vitamin-mineral Drink Envirocomplex Prenatal Vitamin and Mineral Supplement Vitamin B Complex Tab Enrich Core Pack - Children Vitamin and Mineral Supplement Carbassist Tablets Vita-vim - Tab Vit B Complex Plus Vit C 550mg Vitamin B Complex + C 300mg Cap Original Bioscal Forte Multi-vitamin Supplement Capsules Vitamin and Mineral Supplement - Liq Vigem 12 Liquid Twin Ultra Liquid Lemon-lime Flavor Multi #2 Formula D.S. Hill.vite Nutri-Tab OB FolaMed DHA B-complex PNV Tabs 29-1 Corvite Multivit with Fluoride Vyqua Vitasure Multi 12 Injection Multi Plex I - Tab Flintstones Multiple Vitamins Tab Livita Children Multi Vitamin - Mineral Prenatal Mega Antioxidant Stress B Complex With C and E Tab Vit B Complex Ctr Cedevita Plus Vitamin Supplement Poly-VI-flor Vitrexyl plus Iron Viva CT Prenatal Somavit Brand Vitamins and Minerals Complex Vitamin & Mineral Formula 1 Dietary Supplement Beminal W C Fortis Inj Supplement De Multivitamines Infusion Arome Fruits Rouges Multi-Vitamin Multi Vite Liq Adult Multi Vitamin Drops with Fluoride Mvc 9 Plus 3 Inj Geritol Liquid Adeks - Dps PR Natal 400 Stress B&c Tab Twin Opti Pwr Vita-Pac Hypo Vites Tab DuetDHA Balanced Avon Vitadvance Multi-kids Complete Grand Master Formula Tab Materna-tab Multi - N.T.O.x Formula - Tab Paramettes Adults Tandem Plus Pnv-OB-dha Folica BE One Per Day Vitamin and Mineral Dietary Supplement Q.T. #4 Vitamin and Mineral Dietary Supplement Davimet with Fluoride 24 Multivitamins + Minerals Stress B With 1000 Mg Vitamin C Virt Vite GT Vitamine B1 Tab 100mg USP Vita-B Natalvirt Ca Zatean-Pn Beminal Fortis Elx Hemarexin Tab Synergistic Manganese Capsules Multiple Vitamins With Minerals Tablets Betaxin Liq 100mg/ml Childrens Chewab Vitamin W Chel Minerals Childrens Chewable Multivitamins Adult Infuvite Multiple Vitamins B6 Plus Tab Hi Potency Balanced B-100 Complex - Tab Poly-Vi-Flor Revit Multi-vitamins and Minerals One Tablet Daily Mens Formula Thiamine Hydrochloride Inj 100mg/ml Bugs Bunny and Friends Multiple Vitamins Vita B + C 500 Tab CitraNatal DHA Focalgin CA Stress Forte Plus Lipotropic Factors Stress B Capsules With Vitamin C Natural Source Spectrum With Beta Carotene Tricare Prenatal Children's Chewable Tab Vitamin B + C Cap Dayavite Multitol-M Hi Potency Stress B Tension With C Multitam Penta-thion Pwr Megavites Tab Swiss Total One B Complex W C Forte Cap Beminal With C Fortis Cap Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Maxum Multi-vite B Totum 500 Vitafol Ultra B50 B Complex Tab Iron Polysaccharides Folic Acid DHA Virt-Nate DHA Bev B-150
Indication	For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.
Categories	Alimentary Tract and Metabolism Diet, Food, and Nutrition Food Growth Substances Micronutrients OCT1 substrates OCT2 Inhibitors Physiological Phenomena Pyrimidines Sulfur Compounds Thiazoles Vitamin B Complex Vitamins
ATC-Code	A11DA01
CAS number	70-16-6

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Pyruvate dehydrogenase E1 component	MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVN...	unknown	cofactor
Cytochrome P450 4B1	MVPSFLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPP...	unknown	inducer
Thiamine pyrophosphokinase 1	MEHAFTPLEPLLSTGNLKYCLVILNQPLDNYFRHLWNKALLRACADGGAN...	unknown	substrate
Nucleoside diphosphate phosphatase ENTPD5	MATSWGTVFFMLVVSCVCSAVSHRNQQTWFEGIFLSSMCPINVSASTLYG...	unknown	substrate
Thiamine-triphosphatase	MAQGLIEVERKFLPGPGTEERLQELGGTLEYRVTFRDTYYDTPELSLMQA...	unknown	substrate
Albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown	binder
Solute carrier family 22 member 2	MPTTVDDVLEHGGEFHFFQKQMFFLLALLSATFAPIYVGIVFLGFTPDHR...	unknown	inhibitor
Solute carrier family 22 member 1	MPTVDDILEQVGESGWFQKQAFLILCLLSAAFAPICVGIVFLGFTPDHHC...	unknown	substrate
Organic cation/carnitine transporter 2	MRDYDEVTAFLGEWGPFQRLIFFLLSASIIPNGFTGLSSVFLIATPEHRC...	unknown	inhibitor
Thiamine transporter 1	MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSE...	unknown	substrate
Thiamine transporter 2	MDCYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAE...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682