VIV

(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL

Find entries where: VIV

is present as a standalone ligand in 9 entries

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Chemical Component Summary
Name	(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-TRIMETHYLTRIDECYL]CHROMAN-6-OL
Identifiers	(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol
Formula	C₂₉ H₅₀ O₂
Molecular Weight	430.706
Type	NON-POLYMER
Isomeric SMILES	Cc1c(c2c(c(c1O)C)CC[C@@](O2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C
InChI	InChI=1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1
InChIKey	GVJHHUAWPYXKBD-IEOSBIPESA-N

Chemical Details
Formal Charge	0
Atom Count	81
Chiral Atom Count	3
Bond Count	82
Aromatic Bond Count	6

Drug Info: DrugBank

DrugBank ID	DB00163 ?
Name	Vitamin E
Groups	approved nutraceutical vet_approved
Description	In 1922, vitamin E was demonstrated to be an essential nutrient[A32448]. Vitamin E is a term used to describe 8 different fat soluble tocopherols and tocotrienols, alpha-tocopherol being the most biologically active[A176104]. Vitamin E acts as an antioxidant, protecting cell membranes from oxidative damage[A176104]. The antioxidant effects are currently being researched for use in the treatment of diseases causing bone loss, cardiovascular diseases, diabetes mellitus and associated comorbidities, eye diseases, inflammatory diseases (including skin conditions), lipid disorders, neurological diseases, and radiation damage[A176369]. Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally considered safe by the FDA[FDA Label].
Synonyms	Vitamin E alpha-tocopherol d-α-tocopherol 5,7,8-trimethyltocol (+)-α-tocopherol (2R,4'R,8'R)-α-tocopherol (R,R,R)-α-tocopherol
Brand Names	Vitamin E Cap 800unit USP Vie-CA-rad Capsules Phytomin E Cap 200unit Triveen-PRx RNF Multi #2 Nutra Boost Super Ao Formula Vit E 400unit W Selenium 50mcg RE Prenatal Multivitamin with Iron Vita-vim - Tab Nexa Plus Formula F.E.S. Vitamins Tab Food Nutrition Inc. Men's Vitamin and Mineral Supplement Tozal Vitamin E 1000 I.U. (natural Source) Formula Cw Floriva Vitamine E 400iu Cap Nutrol E 200 Cap Multi-Vitamin Luna Vitamin and Mineral Bar for Women Sopalamine/3b Plus C Cellular Formula Organex E 100 Vitaphil DHA Vitamin E Cap 1000unit USP Natural Source Vyqua Beta-CE Cap Virt-Nate DHA Vege 1 Daily Tab PNV-Omega Selenium Plus C & E Aces Caplet Complete One-A-day - Tab Omega-3 Rx Complete WesNate DHA Ch-P Cap Chewable Multiple Vitamins Plus Extra C E 100 Iu Hypo Vites Tab Multi 1000 Acti-D Alphacopherol Cap 400unit Vitamin E 400 + Selenium Cap Acti-D Alphacopherol Cap 800unit Vitamin E 400 I.U. Cap Mega Vitaminerals Cps Capsules VemaVite-PRx 2 with Fish-Based DHA Avengers Vitamin and Mineral Supplement E Vitamin 1000 I.U. (natural Source) Viprot Super Vita-vim With Beta-carotene - Tab Multinate DHA Vitamin E Cap 400unit Natural Source Folivane-PRx DHA Vitamin D3 Dietary Supplement Vitamin E Cream W Vitamins A and D VITAMIN D3 1.25 MG 50000 IU Dietary Supplement Vitamin E TL-Select DHA Mega Plex III - Pck Black Currant Seed Oil Cap Vitamin E 25 Iu Thuna's Relnate DHA Selenium 200mcg Plus C & E Tab Vitamin E Cap USP 200iu Vitamin E Cap 200iu Virt-Pn DHA Vitamin E Acetate Cap 800t Vitamin E 400 Iu - Capsule Formula Hh Efamol Cap E 100 Iu Capsules Supplements De Vitamines Et Mineraux Vitamine E 800 I.U. PreNexa Multivit with Fluoride E-gems-M Vitafol Plus Vitamin E Capsules 200unit O-Cal FA multivitamin Fem - Protect Liquid Vitamin E Pre-Tabs DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Vitamines Et Mineraux Enfants 970 PreQue 10 Inner Health Vitamin Supplement Capsules Multi-vitamines Enfants Comprime CitraNatal Harmony 3.0 Healing Ointment With Vitamin E Silexin Vitamine E 100ui Capsule Vitafol One natelle COMPLETE Nexa Select Vitamin E U.S.P. 200 I.U. - Cap Maltlevol 12 Liq FolaMed DHA Organex E 800 Twin Opti Pwr Original Bioscal Forte Multi-vitamin Supplement Capsules PM Caps Vitamin E Cap 200iu Nf Natural Source Liqui Vita Vitamin E Cap 1000iu Animal Shapes Am Caps Childrens Chew Multi Vitamin Tab Kanga-V Multivitamins & Minerals Vitamin E Ointment 50unit/gm Vitamine E 400 U.I. NovaMV Multivitamin Emuol V Selenium + E WesCap-PN DHA Swiss One RE Nata OB Complete One A Day Tab Organex E 400 Vitamine E 800 Ui Naturelle -cap OB Complete Gold Ultimate Tab Multi-Vit-Flor Vitamin E Cap 200unit Vita-E Totalvit Plus Virt-Select PRENATAL/POSTNATAL Acti-copherols 200 Cap Extra Once A Day Vitaminol Vitamin E 400 Iu Vitamin E Capsules 400iu Vitamin E 200 I.U. (natural Source) Leritone Magnesium & Vitamine E Prenate Elite Vitamin E Caps USP 200unit Virt-PN Plus Childrens Multiple Vit and Min Chew Tab E 200 Cap Natural 200unit Multi 12 Injection Vitamin E 200 I.U. Cap Natural Source Vitamin E 400 Iu Swiss One Multi Vit & Chel Min Tab A.C.E.S. Capsules Q-10 Extra -cap Mr. Tumee Multi-vitamin Twin G.F. Powder Vanilla Flavor Nexa Select Rx Prenatal Vitamin with Plant-Based DHA Multivitamins and Minerals With Betacarotene Tablets Natural Source Vitamine E Capsules Vitamin E Cap 1000unit Multivitamins and Minerals for Women Vitamin E 200 Iu Capsules Cavan Prenatal Diacomp - Cap Poly-Vi-Sol Cell-wise Cedevita Sugar-free Vitamin Supplement Collag-EN TriStart FREE Z-force Vitamin and Mineral Supplement Selenium '100' Plus C&e Vitamine E 100cap Card-floe II Tab Vitamin E 400 I.U. (natural Source) Gnc Natural Source Ultra E 400 - Cap One Tablet Daily Mens Formula Formula Cw-caplet Udamin Sp Vitamin E Plus Cap 200units Multi Plex II - Tab Feminex 300 Tab Vitamine E Creme 250unit/ml Multi Flow Tablets Twin G.F. Powder Onccor Multivitamin with 0.25 mg Fluoride Vitaplex Thera Q Plus Vitamine E 100 I.U. E 400 Iu Vitamune Swiss One Timed Release Tab Advanced AM PM Vitamin E Capsules USP 400 I.U. Swiss One Multivitamin and Mineral Caplet Poly-VI-flor Usana Megavitamin Tablets - Tab Vitamin E and Coq10 Aces Formula/formule A A S Vitamin E Cap 400unit USP Nat Source Vitaphil 90 DHA Hyper E Tab Vitamin E Cap USP 100iu Evening Primrose Oil Cap 500mg W Vit E Rulavite DHA Liqui-E 27 Units/ml Super Gardialine Cap 100iu Senior Multi One Rocky Mountain Multiple Vit and Min Mega Tab P-plus Natelle One Coq10 With E400 Iu Tricare Prenatal DHA One Rx Multivitamin Vitamines Et Mineraux Comprimes Vitalife - Capsule Natural Source Vitamin E Vitamin E Cap 800unit M.V.I. Paediatric E 100 Cap Natural 100unit Coenzyme Q10 + Swical-energy 3e Age Synergistic Selenium FolaGent DHA Vitamin E 200iu Thuna's TriStart ONE Zatean-Pn Plus Multi Plex I - Tab Vitamin E 400 Iu and Selenium 100mcg NovaFerrum Multivitamin with Iron Pediatric Drops Vitamine E Capsules 25ui Sveets Vitamin E 30unit Ont Natural Enrich Core Pack - Children Vitamin and Mineral Supplement Childrens Chewable Tab Vitamin E 200iu Chewable Multiple Vitamins Tab Kimchi Vitamin chewable multivitamin Floriva Plus Vitamin E 400iu Dr. Waltons Baby Powder Vitafol-OB Plus DHA Prenatal Supplement Plus DHA Vitamin E Ont 1000unit Tricare Prenatal DHA One Stress Tab With Iron and Vitamin E Virt-PN DHA Poly-Vi-Flor Gummies Multivitamins and Minerals for Young Men Vl Micel E Liq 100unit/ml Hi Potency Multi Tab Liqui Infant Vitamins Vitamin E Cap USP Nat Ratio 200unit Huile D'onagre Vitamin E Mycelized Childrens Multi-vitamin Liq Evening Primrose Oil Cap Kindervites Protect Plus SO 60 Premium Prenatal Vitamine E Cap 400unit Vitamine E 200 Cap Multivitamin with Fluoride Multi Vitamin, Iron and Fluoride Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA Vitamin E Cap 200unit USP Natural Source Multi-kid Renate DHA Olympian Vit E Cap 400unit Mega Plex IV - Pck Manganese 50mg Plus B1 & E Tab Multi II IV Vi Tab Formula-4 Sx Multivitamin and Mineral VITAFOL Gummies Daily Energy Brand Vitamin & Mineral Drink Mix Vitamine E Cap USP 800unit Nutrol E-400 Plus Zinc Et Selenium Cap Vitamin E 400unit Cap TL-Care DHA Multiple Vitamins Plus Iron Tab Multivitamins and Minerals for Young Women Prost-10 Vitamin and Mineral Supplement Vitamin E Capsules U.S.P. 400 I.U. Super Charged Energy Zatean-Pn DHA Vitamin E Cap 400unit MVC-Fluoride Vitamin E 1000iu VirtPrex Pro E Cap 200unit Mlc Vital Be-100 Reliv So Sense Daily Vitamin Supplement Tricare Prenatal DHA One With Folate 50 Plus Women's Change Formula Classic Swiss One 10 Multivitamin and Mineral Tab Vitamine E 200 U.I. E-400 Cap 400unit Re Ob 90 DHA Bear Essentials Vitamin E Ont 30unit/gm Vasula Tab Niron Komplete Children's Chewable Multivitamin and Multimineral Multivitamin with 1.0 mg Fluoride Super Kids Chewable Multivitamin Multimineral (chewable Tablets) Mycellized Vit E Liq 150unit/ml One A Day Advance Adults 50+ Multi Spectrum - Tablet Bio-efa Borage Gla 240 Cap Natural Source Vitamin E 800 Iu Prenaissance Nutria Fem Time Tab Adrien Gagnon Formule A-C-E + Selenium Nata Komplete Virt-Pn Vitamine E Cap 100iu Folet One Vitafol Caplet Gnc Natural Source Ultra E 1000 - Cap For-2 Men's Biomultiple Vitamin and Mineral Supplement Tma Tab antistressSAN Multinate DHA Extra Bye Bye Burn Lot Vitamine E Cap 200unit Co-q10 M.R.B. 100mg and Vitamin E Beta-carotene,vitamin C,e and Selenium Combo Great Day/am Formula Tab Vitamin E Cap USP 1000unit Taron-prex Prenatal Calcium PNV Cedevita Plus Vitamin Supplement Beta-carotene 10,000 Iu With Vitamins C & E Phytomin E Cap 800unit Multi Vitamin and Fluoride Maxine Vitamin and Mineral Supplement Vitamin E 100 Iu Natural Source Multitabs Vitamin E Cap 200unit Natural Source NovaDHA Baby DHA Beta A With Vitamins C and E Plus Selenium Vitamine E Caps 800unit USP Multi Vitamines - Liq Women's Biomultiple Vitamin and Mineral Supplement Evening Primrose Oil + Vit E Cap H.W. Children's Chewable Multi Vit & Mineral Rogenic Revitalize Multi-vitamin and Mineral Complex Vitamin E 800 I.U. Longevit-E - Capsule Prenatal Mega Antioxidant MultiVitamin with Fluoride Drops Adeks - Dps Vol-Plus Sincera - Tablets Webber Vitamin E Cap 400unit Original Natural Source Vitamin E 1000 Iu NESTABS DHA Prenatal Multi-vitamin/Mineral Supplement with DHA/EPA Stress Tab With Zinc, Copper and Vitamin E Vitamin E Pure 800 I.U. Now E-400 Vitamine E Cap 100unit Vitafol OB Caplet Doctor's Choice Brand for Men Dr. Chen's Men's Formula Earthpals Children's Chewables Multi-vitamin & Mineral Tablets Tianshi Calcium With Natural Source Vitamin E Softgel Capsules Multi Enfants Tab C.V. Formula Hoa 1 Keylosa C-Nate DHA Webber Vitamin E Cap 400unit Natural Source Evening Primrose Oil With Vitamin E MultiVitamin, Iron and Fluoride Drops Selenion Multi-force for Women Tab Multivitamins and Minerals for Men Reaphirm Plant Source DHA Vp-pnv-dha 24 Multivitamins + Minerals Femitab Tab Vege Swiss One Multivitamin W Chel Mins Tab Poly-Vi-Flor Prenate Essential Multivitamins W Minerals Extra Strength E 400iu W Selenium 100mcg Cavan-EC SOD DHA Vitamin E With Selenium and Zinc Vitamin E Cap 800 Unit Natural Vita Balance 2000 Renate L-Methyl PNV DHA TL-Select Liquical Vitamin and Mineral Supp Formula 1 Co-q10 M.R.B. 60mg Maltlevol Liq Nitro Vites - Tab Vitafol Fe Plus Vitamin E Cap 100unit USP Natural Source PreNexa premier Multi-Nate 30 Webber Vitamin E Cap 800unit Original Bio-efa Borage Gla 90 Cap Leritone Antistress Vitamin E Cap USP 400unit Vision E - 134iu/cap Vitamines Et Mineraux Vista Advanced AREDS2 Formula Vitamine E25vi Capsule Multi-force for Adults Tab Multicaps Extra 11 Tendera-OB TL-Fluorivite CitraNatal Essence Formula F L W Pro-gla Caps RE Nata Vita-vim With Beta-carotene - Tab Vitamin E Cap 400iu CitraNatal Assure Cell-wise Natural Source E-prime Vitamin E Supplement VitaPhil Aide Multiple Vit Plus Iron Tab Vitamin E Ont Maintain Multiple Vitamin & Minerals RE FAC-x One A Day Multiple Vit W Minerals Prenatal Vi-min Gamma Oil Homosistrox Capsules Strovite Forte Caplet Avon Nutrivance Vitamin E Plus Iron Complex OB Complete 400 Mangadyn Real Vitamin Supplement Cap Vitamin E Capsules 800iu Geri-plus Cap PreGen DHA Vitamin E Cap 100unit Adeks Tablets CitraNatal Medley Nutra-clear Multipack II Acne C-Patch Daily Supplement Packs PreFol-DHA Spark Cap Se-Plete DHA Multi Tabs Natural Source Spectrum With Beta Carotene Sopalamine 3b Plus Vitamin E 400 Iu Capsules Vitamin E 400 Iu USP Maxum Multi-vite Prenatal E 200 Cap 200unit Aces Tab Vitamin E Cap 50unit Extra-Virt Plus DHA Vimeral Tab Vitamin E Cap 800iunf Natural OB Complete DHA Vitamin E 1000 Iu - Water Soluble Children's Chewable Vit and Min Tab Multiple Vitamins and Minerals Capsules
Indication	Vitamin E supplementation is indicated for treatment of vitamin E deficiency which can occur in cystic fibrosis, cholestasis and severe liver disease, abetalipoproteinemia or simply poor diet[A176104,L3063].
Categories	Antioxidants Basic Ointments and Protectants Benzopyrans Biological Factors Compounds used in a research, industrial, or household setting Cytochrome P-450 CYP3A Inducers Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inducers Cytochrome P-450 CYP3A4 Inducers (strength unknown) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Substrates Diet, Food, and Nutrition Dietary Supplements Food Growth Substances Heterocyclic Compounds, Fused-Ring Micronutrients Physiological Phenomena Protective Agents Pyrans Supplements Vitamin E Vitamin E, analogs & derivatives Vitamins Vitamins (Fat Soluble)
CAS number	59-02-9

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
SEC14-like protein 4	MSSRVGDLSPQQQEALARFRENLQDLLPILPNADDYFLLRWLRARNFDLQ...	unknown
SEC14-like protein 3	MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQ...	unknown
SEC14-like protein 2	MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQ...	unknown
Nuclear receptor subfamily 1 group I member 2	MEVRPKESWNHADFVHCEDTESVPGKPSVNADEEVGGPQICRVCGDKATG...	unknown
Protein kinase C beta type	MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFC...	unknown
Arachidonate 5-lipoxygenase	MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGA...	unknown
Protein kinase C alpha type	MADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFC...	unknown
Diacylglycerol kinase alpha	MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGY...	unknown
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform	MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRC...	unknown
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform	MDEKVFTKELDQWIEQLNECKQLSESQVKSLCEKAKEILTKESNVQEVRC...	unknown
Glutathione S-transferase P	MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLY...	unknown	inhibitor
Glutathione S-transferase omega-1	MSGESARSLGKGSAPPGPVPEGSIRIYSMRFCPFAERTRLVLKAKGIRHE...	unknown	inhibitor
Glutathione S-transferase Mu 3	MSCESSMVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQW...	unknown	inducer
Glutamate--cysteine ligase catalytic subunit	MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDE...	unknown	inducer
NAD(P)H dehydrogenase [quinone] 1	MVGRRALIVLAHSERTSFNYAMKEAAAAALKKKGWEVVESDLYAMNFNPI...	unknown	inducer
Heme oxygenase 1	MERPQPDSMPQDLSEALKEATKEVHTQAENAEFMRNFQKGQVTRDGFKLV...	unknown	inducer
Superoxide dismutase [Cu-Zn]	MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHE...	unknown	inducer
Cytochrome P450 3A4	MALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNI...	unknown	substrate,inducer
Glutathione S-transferase A2	MAEKPKLHYSNIRGRMESIRWLLAAAGVEFEEKFIKSAEDLDKLRNDGYL...	unknown	inducer
SEC14-like protein 2	MSGRVGDLSPRQKEALAKFRENVQDVLPALPNPDDYFLLRWLRARSFDLQ...	unknown	binder
SEC14-like protein 3	MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQ...	unknown	binder
Phospholipid transfer protein	MALFGALFLALLAGAHAEFPGCKIRVTSKALELVKQEGLRFLEQELETIT...	unknown	binder
Alpha-tocopherol transfer protein	MAEARSQPSAGPQLNALPDHSPLLQPGLAALRRRAREAGVPLAPLPLTDS...	unknown	binder
Scavenger receptor class B member 1	MGCSAKARWAAGALGVAGLLCAVLGAVMIVMVPSLIKQQVLKNVRIDPSS...	unknown	substrate
ATP-binding cassette sub-family A member 1	MACWPQLRLLLWKNLTFRRRQTCQLLLEVAWPLFIFLILISVRLSYPPYE...	unknown	substrate
Niemann-Pick C1-like protein 1	MAEAGLRGWLLWALLLRLAQSEPYTTIHQPGYCAFYDECGKNPELSGSLM...	unknown	substrate
ATP-binding cassette sub-family G member 1	MACLMAAFSVGTAMNASSYSAEMTEPKSVCVSVDEVVSSNMEATETDLLN...	unknown	substrate
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Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682