DrugBank ID DB00878 ? Name Chlorhexidine Groups approved vet_approved withdrawn Description Chlorhexidine is a broad-spectrum antimicrobial biguanide used as a topical antiseptic and in dental practice for the treatment of inflammatory dental conditions caused by microorganisms.[L11512] It is one of the most common skin and mucous membrane antiseptic agents in use today.[A190417] The molecule itself is a cationic bis-guanide consisting of two 4-chlorophenyl rings and two biguanide groups joined by a central hexamethylene chain.[A190453] Topical chlorhexidine for disinfection, as well as oral rinses for dental use, carries activity against a broad range of pathogens including bacteria, yeasts, and viruses.[L11518,L11512,A190453] Chlorhexidine was developed in the UK by Imperial Chemical Industries in the early 1950s[A190474] and was introduced to the US in the 1970s.[L11572] The FDA withdrew its approval for the use of chlorhexidine gluconate topical tincture 0.5%, due to a significant number of reports concerning chemical and thermal burns associated with the use of this product.[L43942,L44027] Other formulations of chlorhexidine continue to be available. Synonyms Chlorhexidinum Cloresidina Chlorhexidine hydrochloride N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide Chlorhexidine acetate
Chlorhexidine gluconate 1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide) Chlorhexidin Chlorhexidine Clorhexidina more Brand Names WhyteDerm SurgiPak Hibitane Skin Cleanser 2% Steri-clean Dexidin 20 Ezy-TM
Flamazine C Foaming Chlorhexidine Gluconate Hibiclens for Georgia Pacific Ic-gel Germi-stat 2% Foaming Liquid Skinvisible Chlorhexidine Formula Hand Sanitizer Lotion Dr. Zheng s acteriostatic gel PhysiciansCare Eyewash Station Additive Concentrate Burn O Sol Spray 3m Soluprep Sponge Quick-drying rinse-free hand skin disinfectant Germi Stat Gel 2% Maxiclens Chlorhexidine Gluconate Liquid Solution, 4% Peridex Oral Rinse 0.12% Chlorhexidine Alcohol Free Bactoshield Chg 4% Dexidin Liq 4% Hand Sanitizer Biokaab Denticare Chlorhexidine Gluconate Oral Rinse 0.12% 3M SoluPrep Skin antisepsis, oral cleansing, nasal antisepsis Hibistat Purmist JIANLIANG Antibacterial Sprays 10mL Dexidin 2 Solution Tai Yu Ling Antibacterial Sprays 10mL Surgical Continuum System Chlorhexidine Gluconate Solution 0.75% Antiseptic Scrub-stat IV 4% Bactoshield Chg 2% QCare Rx Oral Cleansing and Suctioning System, Q2 E-Z Scrub 107 Chloraprep Liq 0.5% HandSoap Disinfectant Spray(Speedy effect type) Hygenipak 2% Chg Foaming Skin Cleanser Hygienipak 4% Chg Foaming Skin Cleanser Instillagel Oronine H Ointment 1% (Qiqing) Chlorhexidine Gluconate Alcohol Disinfectant PMS-chlorhexidine Rouhex G 20% Akilgeld Hand Sanitizer Dexidin 2 Detergent Rouhex G Liq 2% Dr. Dean BD E-Z Scrub 107 Chlorhexidine Gluconate Solution USP 20% Chlorhexidine Gluconate 0.12% Oral Rinse Chlorhexidine Liq 0.05% Sanital Antibacterial Hand Soap Dermawerx Surgical PrePak Smart Sense Antiseptic Skin Cleanser Oral Cleansing and Suctioning System, q2 Pro-dentx Chlorhexidene Oral Rinse Stanhexidine Red Tincture 0.5% Betalido-C Soluprep Wipe Cardinal Health Antiseptic Skin Cleanser Foam Care Chg Surgical Hand Scrub Calgon Vestal 2% Chg Antimicrob.skin Cleans. Sunberry Rinse free Hand Sanitizer Provon Antiseptic Lotion Soap With 2% Chg Hibitane Skin Cleanser 4% Zappy Ultimate Antiseptic Wipes Chlorhexidine Gluconante Liquivida Hydration Cida-stat Liq Avagard Chg Loris - I.V. Soluprep AQ Sponge Pre-moistened Towelette Chlorhexidine Gluconate, 0.12% Oral Rinse Mlk F4-C SANIDEP Advanced Sanitizer with Organic Extracts Dexidin 0.5 Solution Liszt Hand sanitizer without washing Dermawerx Surgical Plus Pak DEQGEL Advanced Hand Sanitizer Hand Sanitizer Gel Biokaab Chlorhexidine Gluconate, 0.12% Oral Rinse Solution Dr. Luke Molluscum Wart Remover Antiseptic Skin Cleanser Exidine-2 CHG Laura Line Antibacterial Cream Soap 2% E-Z Scrub 747 4% Sky Oral Rinse Antiseptic Skin Cleanser Peridex ReadyPrep CHG DermacinRx Clorhexacin Hibidil Bactoshield CHG Chlorhexidine Gluconate Solution Soft Care 2% Chg Antimicrobial Skin Cleanser Chlorhexidine B-good Hand and Skin Disinfecting Agent Serdaen Dermsafe Pc Scrub Care Exidine -4 CHG Soluprep Qd Solution Foaming Hand Wash DermacinRx Surgical PharmaPak Peridex Oral Rinse Prevantics swabstick Rouhex G 4% Scrub, Scrub-Stat Baxedin 2% - 70% CliniClean Salvesept Crm Prevora Stage 1 Alcohol Antibacterial Wipes Antimicrobial Foam Handwash ICEKING Skin Expert Refreshing Body Roller Zedoary Oils Feminine Antibacterial Gels Hand wipes SAITENM Health Wet wipes Sterixin 0.05% Hygienium Bei Ling Tong Bao Er Zheng Yuan Antibacterial Creams Betasept NUPRO Chlorhexidine Gluconate Smart San CHG Soluprep Ld Sponge Chlorhexseptic-liq 0.5mg/ml Pre and Post Sx Pouch Jisberry Hand Sanitizer Selpak Antibacterial Wet Wipes Scrub Care Surgical Scrub Brush/nail Cleaner With Exidine 4 Stanhexidine 20% Hexirex Antiseptic Skin Cleanser Soluprep AQ Swab Periogard (Chlorhexidine Gluconate) QCare Rx Oral Cleansing and Suctioning System, Q4 Purell CS Foam Handwash 2% CHG Soluprep AQ Oris Chx Prevantics Swab Foaming Hand Antiseptic With Chg 2% Medifresh Hand Skin Antiseptic Disinfectant Wet Wipes Steri-stat Liq 20% Bioprep Solunet C Brosse 4% Oral Cleansing and Suctioning System, q4 Chlorhexidine Solution Soft Care Antiseptic Hand Soap Antiseptic Foam Handwash Hibistat Germicidal Hand Rinse Oro Clear Periogard Spray On Plastic Bandage Aerosol Dr. Luke Wart Remover KleerSight Chlorhexidine Gluconate 0.12% Oral Rinse, USP NuSurgePak Surgical Prep/CarePak Disinfectant Fabric Wash Cida-stat Foam Baxedin Pre-OP Disinfectant Wet Tissues First Aid Antiseptic Skin Cleanser Hibiclens Chlorhexidine and Isopropyl Alcohol Prep Pads Antiseptic Body Cleanser Chlorhexidine Gluconate Solution 0.05% Anti Mucedine Feminine Wash Surgical and healthcare personnel hand antiseptic with moisturizers Oro-clense LARA MED Antibacterial Wet Wipes Akilspray Hand Sanitizer Hand Sanitizer Wart Remover Ointment. Steri-stat Liq 4.0% Hibitane Skin Cleanser Ultrastat Bactoshield CHG Scrub Hexifoam-skin Disinfectant Aer 1% Freeman Packing Alcohol Wipe Soluprep Noble 75% Alcohol Wipes 3M Avagard Antiseptic Cleansing Wipes Dermsafe Chlorhexidine Gluconate Hand Sanitizer Lotion Baxedin Antiseptic Cleanser Solution Septi-san Hands-free skin sanitizer Savlodil CleanCare Chlorhexidine Gluconate 0.12% Oral Rinse Stanhexidine 2% With Isopropyl Alcohol 4% Endure 400 Scrub-Stat 4 Scrub Care Seaqua X Soluprep Antiseptic Skin Cleanser Sponge Sterigel Plus Spectro Tar Antiseptic Shampoo Chlorhexidine Gluconate Eyewash Station Additive Concentrate Purell Antimicrobial Foam Handwash 2% Chg Bactoshield Henry Schein Antimicrobial Skin Cleanser Antiseptic First Aid Spray Euro-chlorhexidine Hibiclens Antiseptic/antimicrobial Skin Cleanser Bacti-stat Chg Antimicrobial Skin Cleanser Soluprep Antiseptic Skin Cleanser Preoperative Kit Chloraprep Swabsticks Soluprep Applicator Chlorhexidine Gluconate Oral Rinse Ostar Antimicrobial Hand Soap 2% - Liquid HYDROGEL ESSENCE Antimicrobial Virginal Gel. Loris I.V. Pro - Prefilled Applicator With Solution Antibacterial Protective Hand Rougier Clean Derm Yu Ding Antibacterial Sprays 10mL Dyna-Hex 4 Dyna-hex 2 Spectro Gram 2 Skin Cleanser Anti-bac Hand Avidene Surgical Scrub Foam Safe Chlorhexidine gluconate Paroex Germi-stat 0.5% Antiseptic Prep Gel Chinese Herb Essence Bacteriostatic Feminine Wash Scrub-Stat Aplicare Antiseptic Chlorhexidine Gluconate Halyard Chlorhexidine Gluconate Purell Antimicrobial Foam Soluprep AQ Wipe Chloraprep Dyural LM- C Aplicare Chlorhexidine Gluconate 2% Solution Chlorhexidine 4% Antiseptic Hand Wash Savlon Hospital Concentrate (Fruli) Quick-Dry Disposable Hand Sanitizer Dyna-hex 4 Chlorhexidine Gluconate Applicator Prevantics Maxi Swabstick DermacinRx Surgical ComboPak Gelato Chlorohexidine Baxedin Liq 20% Motherwort Herb Feminine Antibacterial Gels Microban Medical Chlorhexidine-cetrimide Soltn Conc Chlora-cleanze Antiseptic Solution Hibitane Skin Cleanser Liq 4% KIMVENT ORAL CARE Q4 Kit WITH CHG Loris I.V. Pro - Sponge Steri-stat Tincture (tinted) Antis Prep Gel DASH Chlorhexidine Gluconate 0.12% Oral Rinse Scrub Care Exidine-2 CHG Wart Removal Pen Alcohol Disinfectant Wipes Stat Touch 2 Antimicrobial Skin Cleanser Plant Herb Based Bacteriostatic Feminine Wash Stanhexidine 4% With Isopropyl Alcohol 4% Germi-stat Prep Gel Soluprep AQ Applicator X-pur Chlorhexidine Laura Line Chlorhexidine Antiseptic Soap Kimvent Oral Care Q2 Kit with CHG Cardinal Health Loris 2% Chg Wipe/serviette Pre-Scrub II Surgical Hand Scrub Rugby Antiseptic Skin Cleanser Soluprep Qd Wipe Dyna-Hex 75 Soluprep Swab Scrub, Scrub-Stat, Foam Safe, Micro-Guard QCare Rx Oral Cleansing and Suctioning System Major Oral Rinse Hygenipak 2% Chg Skin Cleanser Quick-Drying Hand Sanitizer PS1 Aciurgy Pack Acclean Chlorhexidine Gluconate 0.12% Oral Rinse Dyna-Hex 2 Prevantics Swabstick Chlorhexidine and Isopropyl Alcohol Swabsticks Foster and Thrive ChloraPrep One-Step PMS-chlorhexidine Without Alcohol Steri-stat Liq 2.0% Loris 2% Chg Solution PS2 Aciurgy Pack Germi Stat Gel 4% Hexicinide Protective Hand QCare Rx Petite Oral Cleansing and Suctioning System Q2 Oral Care Kit with CHG 3M SoluPrep S Bactigras Wart removal BD E-Z Scrub Scrub Stat 4 Foam Liq Calgon Vestal 4% Chg Antimicrob.skin Cleans. Periogard Alcohol Free Bactoshield CHG Chlorhexidine Gluconate Perioselect Antimicrobial Sol 0.12% Bioprep Liq Soluprep Qd Swab Loris 2% Chg Body Cleanser/nettoyant Pour Le Corps ChloraPrep Swabstick Dyural 80 LM-C Hospicare 40R Adult Body Wipes Chlorhexidine 2% Antiseptic Hand Wash Loris I.V. Pro - Swabstick Chlorhexidine 0.5% Liq Skin Antisepsis, Oral Cleansing and Nasal Antisepsis System E-Z Scrub Antimicrobial Foam Solution Containing 4% Chg Gum Paroex Spray On Plastic Bandage Non-aerosol PerioChip Stanhexidine Aqueous 2% With 4% Isopropyl Alcohol Rougier Vap-chlorhexidine Gluconate 2% W/V Dexlido M-C Endure 420 Cida-Stat Hygienipak 4% Chg Skin Cleanser Antiseptic Lotion Soap 2% Provon Antimicrobial Foam Handwash CLIP Liquid Sanitizer Hand Wipes Maxiclens Chlorhexidine gluconate Liquid Solution, 4% Denti-Care Denti-Rinse Chlorhexidine Gluconate Oral Rinse more Indication Chlorhexidine is available over-the-counter in various formulations (e.g. solution, sponge, cloth, swab) as a topical antiseptic to sanitize prior to surgeries and/or medical procedures.[L11518,L11521,L11527,L11533] Dental formulations, available by prescription only, include an oral rinse indicated for the treatment of gingivitis[L11512] and a slow-release "chip" which is inserted into periodontal pockets and is indicated for the reduction of pocket depth in adult patients with periodontitis as an adjunct therapy to dental scaling and root planing procedures.[L11536] Categories Alimentary Tract and Metabolism Amidines Anti-Infective Agents Anti-Infective Agents, Local Antiinfectives and Antiseptics for Local Oral Treatment
Antiseptics and Disinfectants Biguanides Biguanides and Amidines Compounds used in a research, industrial, or household setting Decreased Cell Wall Integrity Dental Agents Dermatologicals Disinfectants Guanidines Household Products Irrigating Solutions Medicated Dressings Medicated Dressings With Antiinfectives Miscellaneous Anti-infectives Miscellaneous Local Anti-infectives Mouthwashes Mouthwashes and Gargles Ophthalmological and Otological Preparations Ophthalmologicals Otologicals Sensory Organs Stomatological Preparations Throat Preparations more ATC-Code more CAS number 55-56-1 
