The PDB in JBC



Today, most scientific journals require authors to deposit structural data in the PDB, but that was not always the case. The Journal of Biological Chemistry (JBC) was a pioneer in promoting open access;editors encouraged authors to deposit their structures as early as 1977 and made deposition a requirement for publication in 1989.

As the PDB celebrates its 50th anniversary, JBC has published more structures than any other journal. Highlighting its synergy with the PDB, JBC assembled a collection of JBC Reviews celebrating the scientific areas that have been profoundly touched by the creation of the PDB, and a virtual issue collecting JBC articles that describe a few classic structures and most highly cited papers. These JBC reviews were assembled by Lila Gierasch (JBC) and Helen Berman (Guest Editor).

Explore these classic articles and structures below:


1SNS (replaced by 2SNS): A High Resolution Structure of an Inhibitor Complex of the Extracellular Nuclease of Staphylococcus aureus: I. EXPERIMENTAL PROCEDURES AND CHAIN TRACING. A. Arnone, C.J. Bier, F.A. Cotton, V.W. Day, E.E. Hazen Jr., D.C. Richardson, J.S. Richardson, A. Yonath 1971

2cna: The covalent and three-dimensional structure of concanavalin A. IV. Atomic coordinates, hydrogen bonding, and quaternary structure. G N Reeke Jr, J W Becker, G M Edelman 1975

1gpd: Studies of asymmetry in the three-dimensional structure of lobster D-glyceraldehyde-3-phosphate dehydrogenase. D Moras, KW Olsen, MN Sabesan, M Buehner, GC Ford, MG Rossmann 1975

4DFR: Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate. J T Bolin, D J Filman, D A Matthews, R C Hamlin, J Kraut 1982

3BNA: Reversible bending and helix geometry in a B-DNA dodecamer: CGCGAATTBrCGCG. A V Fratini, M L Kopka, H R Drew, R E Dickerson 1982

2CYP: Crystal structure of yeast cytochrome c peroxidase refined at 1.7-A resolution. B C Finzel, T L Poulos, J Kraut 1984

1HBS: Refined crystal structure of deoxyhemoglobin S. I. Restrained least-squares refinement at 3.0-A resolution. DE A Padlan, W E Love 1985

1PP2: The refined crystal structure of dimeric phospholipase A2 at 2.5 A. Access to a shielded catalytic center. S Brunie, J Bolin, D Gewirth, P B Sigler 1985

3ICB: The refined structure of vitamin D-dependent calcium-binding protein from bovine intestine. Molecular details, ion binding, and implications for the structure of other calcium-binding proteins. D M Szebenyi, K Moffat 1986

5ADH: Interdomain motion in liver alcohol dehydrogenase. Structural and energetic analysis of the hinge bending mode. F Colonna-Cesari, D Perahia, M Karplus, H Eklund, C I Br?d¨¦n, O Tapia 1986

113D: The structure of guanosine-thymidine mismatches in B-DNA at 2.5-A resolution. W.N. Hunter, T. Brown, G. Kneale, N.N. Anand, D. Rabinovich, O. Kennard 1987

4TNC: Refined structure of chicken skeletal muscle troponin C in the two-calcium state at 2-A resolution. K A Satyshur, S T Rao, D Pyzalska, W Drendel, M Greaser, M Sundaralingam 1988

1DCG: The molecular structure of the left-handed Z-DNA double helix at 1.0-? atomic resolution: Geometry, conformation, and ionic interactions of d(CGCGCG). R V Gessner, C A Frederick, G J Quigley, A Rich, A H J Wang 1989

1TNF: The Structure of Tumor Necrosis Factor-¦Á at 2.6 ? Resolution: Implications for receptor binding. M J Eck, S R Sprang 1989

2GLS: Refined atomic model of glutamine synthetase at 3.5 ? resolution. M M Yamashita, R J Almassy, C A Janson, D Cascio, D Eisenberg 1989

5HVP: Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0-A resolution. P.M. Fitzgerald, B.M. McKeever, J.F. VanMiddlesworth, J.P. Springer, J.C. Heimbach, C.T. Leu, W.K. Herber, R.A. Dixon, P.L. Darke 1990

1HEM: Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme. K.P. Wilson, B.A. Malcolm, B.W. Matthews 1992

1WAT: The three-dimensional structure of the ligand-binding domain of a wild-type bacterial chemotaxis receptor. Structural comparison to the cross-linked mutant forms and conformational changes upon ligand binding. J.I. Yeh, H.P. Biemann, J. Pandit, D.E. Koshland, S.H. Kim 1993

1M2C: A New ¦Á-Conotoxin Which Targets ¦Á3¦Â2 Nicotinic Acetylcholine Receptors. G. Edward Cartier, Doju Yoshikami, William R. Gray, Siqin Luo, Baldomero M. Olivera, J. Michael McIntosh Eisenberg 1996

1EEM: Identification, Characterization, and Crystal Structure of the Omega Class Glutathione Transferases. Philip G. Board, Marjorie Coggan, Gareth Chelvanayagam, Simon Easteal, Lars S. Jermiin, Gayle K. Schulte, Dennis E. Danley, Lise R. Hoth, Matthew C. Griffor, Ajith V. Kamath, Michele H. Rosner, Boris A. Chrunyk, David E. Perregaux, Christopher A. Gabel, Kieran F. Geoghegan, Jayvardhan Pandit 2000

1E3K, 1E3G: Structural Evidence for Ligand Specificity in the Binding Domain of the Human Androgen Receptor: IMPLICATIONS FOR PATHOGENIC GENE MUTATIONS. Pedro M. Matias, Peter Donner, Ricardo Coelho, Monica Thomaz, Cristina Peixoto, Sofia Macedo, Norbert Otto, Simone Joschko, Peter Scholz, Anja Wegg, Siegfried B?sler, Martina Sch?fer, Ursula Egner, Maria Arm¨¦nia Carrondo 2000

1E78, 1E7B, 1E7A, 1E7C: Binding of the General Anesthetics Propofol and Halothane to Human Serum Albumin: HIGH RESOLUTION CRYSTAL STRUCTURES. Ananyo A. Bhattacharya, Stephen Curry, Nicholas P. Franks 2000

1DXR: Structural Basis of the Drastically Increased Initial Electron Transfer Rate in the Reaction Center from a Rhodopseudomonas viridis Mutant Described at 2.00-? Resolution. C. Roy D. Lancaster, Marina V. Bibikova, Piera Sabatino, Dieter Oesterhelt, Hartmut Michel 2000

1FX0: The Structure of the Chloroplast F1-ATPase at 3.2 ? Resolution. Georg Groth, Ehmke Pohl 2001

1HA2, 1H9Z: Crystal Structure Analysis of Warfarin Binding to Human Serum Albumin: ANATOMY OF DRUG SITE I. Isabelle Petitpas, Ananyo A. Bhattacharya, Sue Twine, Malcolm East, Stephen Curry 2001

1HUY: Reducing the Environmental Sensitivity of Yellow Fluorescent Protein: MECHANISM AND APPLICATIONS. Oliver Griesbeck, Geoffrey S. Baird, Robert E. Campbell, David A. Zacharias, Roger Y. Tsien 2001

1L0V: Crystallographic Studies of the Escherichia coli Quinol-Fumarate Reductase with Inhibitors Bound to the Quinol-binding Site. Tina M. Iverson, C¨¦sar Luna-Chavez, Laura R. Croal, Gary Cecchini, Douglas C. Rees 2002

1GYC: Crystal Structure of a Laccase from the FungusTrametes versicolor at 1.90-? Resolution Containing a Full Complement of Coppers. Klaus Piontek, Matteo Antorini, Thomas Choinowski 2002

1M14, 1M17: Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor. Jennifer Stamos, Mark X. Sliwkowski, Charles Eigenbrot 2002

1P0P, 1P0M, 1P0I, 1P0Q: Crystal Structure of Human Butyrylcholinesterase and of Its Complexes with Substrate and Products. Yvain Nicolet, Oksana Lockridge, Patrick Masson, Juan C. Fontecilla-Camps, Florian Nachon 2003

1Q5K: Structural Insights and Biological Effects of Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418. Ratan Bhat, Yafeng Xue, Stefan Berg, Sven Hellberg, Mats Orm?, Yvonne Nilsson, Ann-Cathrin Rades?ter, Eva Jerning, Per-Olof Markgren, Thomas Borgeg?rd, Martin Nyl?f, Alfredo Gim¨¦nez-Cassina, F¨¦lix Hern¨¢ndez, Jose J. Lucas, Javier D¨ªaz-Nido, Jes¨²s Avila 2003

1JC1, 1JC0: Investigating Mitochondrial Redox Potential with Redox-sensitive Green Fluorescent Protein Indicators. George T. Hanson, Robert Aggeler, Devin Oglesbee, Mark Cannon, Roderick A. Capaldi, Roger Y. Tsien, S. James Remington 2004

1VF7: Crystal Structure of the Membrane Fusion Protein, MexA, of the Multidrug Transporter in Pseudomonas aeruginosa. Hiroyuki Akama, Takanori Matsuura, Sachiko Kashiwagi, Hiroshi Yoneyama, Shin-ichiro Narita, Tomitake Tsukihara, Atsushi Nakagawa, Taiji Nakae 2004

1T45, 1T46: Structural Basis for the Autoinhibition and STI-571 Inhibition of c-Kit Tyrosine Kinase. Clifford D. Mol, Douglas R. Dougan, Thomas R. Schneider, Robert J. Skene, Michelle L. Kraus, Daniel N. Scheibe, Gyorgy P. Snell, Hua Zou, Bi-Ching Sang, Keith P. Wilson 2004

1R9O: The Structure of Human Cytochrome P450 2C9 Complexed with Flurbiprofen at 2.0-? Resolution. Michael R. Wester, Jason K. Yano, Guillaume A. Schoch, Christine Yang, Keith J. Griffin, C. David Stout, Eric F. Johnson 2004

1TQN: The Structure of Human Microsomal Cytochrome P450 3A4 Determined by X-ray Crystallography to 2.05-? Resolution. Jason K. Yano, Michael R. Wester, Guillaume A. Schoch, Keith J. Griffin, C. David Stout, Eric F. Johnson 2004

1R7G, 1R7F, 1R7E, 1R7D, 1R7C: Structure and Function of the Membrane Anchor Domain of Hepatitis C Virus Nonstructural Protein 5A. Fran?ois Penin, Volker Brass, Nicole Appel, Stephanie Ramboarina, Roland Montserret, Damien Ficheux, Hubert E. Blum, Ralf Bartenschlager, Darius Moradpour 2004

1XQ8: Structure and Dynamics of Micelle-bound Human ¦Á-Synuclein. Tobias S. Ulmer, Ad Bax, Nelson B. Cole, Robert L. Nussbaum, Published in issue: March 11, 2005

2ZMX, 2AHL, 2AHK, 1WXC, 1WX5, 1WX4, 1WX2: Crystallographic Evidence That the Dinuclear Copper Center of Tyrosinase Is Flexible during Catalysis. Yasuyuki Matoba, Takanori Kumagai, Aiko Yamamoto, Hironari Yoshitsu, Masanori Sugiyama 2006

2P1L: Crystal Structure of the Bcl-XL-Beclin 1 Peptide Complex: BECLIN 1 IS A NOVEL BH3-ONLY PROTEIN. Adam Oberstein, Philip D. Jeffrey, Yigong Shi 2007

2ZJD: Structural Basis for Sorting Mechanism of p62 in Selective Autophagy. Yoshinobu Ichimura, Taichi Kumanomidou, Yu-shin Sou, Tsunehiro Mizushima, Junji Ezaki, Takashi Ueno, Eiki Kominami, Takashi Yamane, Keiji Tanaka, Masaaki Komatsu 2008

universo-virtual.com
buytrendz.net
thisforall.net
benchpressgains.com
qthzb.com
mindhunter9.com
dwjqp1.com
secure-signup.net
ahaayy.com
soxtry.com
tressesindia.com
puresybian.com
krpano-chs.com
cre8workshop.com
hdkino.org
peixun021.com
qz786.com
utahperformingartscenter.org
maw-pr.com
zaaksen.com
ypxsptbfd7.com
worldqrmconference.com
shangyuwh.com
eejssdfsdfdfjsd.com
playminecraftfreeonline.com
trekvietnamtour.com
your-business-articles.com
essaywritingservice10.com
hindusamaaj.com
joggingvideo.com
wandercoups.com
onlinenewsofindia.com
worldgraphic-team.com
bnsrz.com
wormblaster.net
tongchengchuyange0004.com
internetknowing.com
breachurch.com
peachesnginburlesque.com
dataarchitectoo.com
clientfunnelformula.com
30pps.com
cherylroll.com
ks2252.com
webmanicura.com
osostore.com
softsmob.com
sofietsshotel.com
facetorch.com
nylawyerreview.com
apapromotions.com
shareparelli.com
goeaglepointe.com
thegreenmanpubphuket.com
karotorossian.com
publicsensor.com
taiwandefence.com
epcsur.com
odskc.com
inzziln.info
leaiiln.info
cq-oa.com
dqtianshun.com
southstills.com
tvtv98.com
thewellington-hotel.com
bccaipiao.com
colectoresindustrialesgs.com
shenanddcg.com
capriartfilmfestival.com
replicabreitlingsale.com
thaiamarinnewtoncorner.com
gkmcww.com
mbnkbj.com
andrewbrennandesign.com
cod54.com
luobinzhang.com
bartoysdirect.com
taquerialoscompadresdc.com
aaoodln.info
amcckln.info
drvrnln.info
dwabmln.info
fcsjoln.info
hlonxln.info
kcmeiln.info
kplrrln.info
fatcatoons.com
91guoys.com
signupforfreehosting.com
faithfirst.net
zjyc28.com
tongchengjinyeyouyue0004.com
nhuan6.com
oldgardensflowers.com
lightupthefloor.com
bahamamamas-stjohns.com
ly2818.com
905onthebay.com
fonemenu.com
notanothermovie.com
ukrainehighclassescort.com
meincmagazine.com
av-5858.com
yallerdawg.com
donkeythemovie.com
corporatehospitalitygroup.com
boboyy88.com
miteinander-lernen.com
dannayconsulting.com
officialtomsshoesoutletstore.com
forsale-amoxil-amoxicillin.net
generictadalafil-canada.net
guitarlessonseastlondon.com
lesliesrestaurants.com
mattyno9.com
nri-homeloans.com
rtgvisas-qatar.com
salbutamolventolinonline.net
sportsinjuries.info
topsedu.xyz
xmxm7.com
x332.xyz
sportstrainingblog.com
autopartspares.com
readguy.net
soniasegreto.com
bobbygdavis.com
wedsna.com
rgkntk.com
bkkmarketplace.com
zxqcwx.com
breakupprogram.com
boxcardc.com
unblockyoutubeindonesia.com
fabulousbookmark.com
beat-the.com
guatemala-sailfishing-vacations-charters.com
magie-marketing.com
kingstonliteracy.com
guitaraffinity.com
eurelookinggoodapparel.com
howtolosecheekfat.net
marioncma.org
oliviadavismusic.com
shantelcampbellrealestate.com
shopleborn13.com
topindiafree.com
v-visitors.net
qazwsxedcokmijn.com
parabis.net
terriesandelin.com
luxuryhomme.com
studyexpanse.com
ronoom.com
djjky.com
053hh.com
originbluei.com
baucishotel.com
33kkn.com
intrinsiqresearch.com
mariaescort-kiev.com
mymaguk.com
sponsored4u.com
crimsonclass.com
bataillenavale.com
searchtile.com
ze-stribrnych-struh.com
zenithalhype.com
modalpkv.com
bouisset-lafforgue.com
useupload.com
37r.net
autoankauf-muenster.com
bantinbongda.net
bilgius.com
brabustermagazine.com
indigrow.org
miicrosofts.net
mysmiletravel.com
selinasims.com
spellcubesapp.com
usa-faction.com
snn01.com
hope-kelley.com
bancodeprofissionais.com
zjccp99.com
liturgycreator.com
weedsmj.com
majorelenco.com
colcollect.com
androidnews-jp.com
hypoallergenicdogsnames.com
dailyupdatez.com
foodphotographyreviews.com
cricutcom-setup.com
chprowebdesign.com
katyrealty-kanepa.com
tasramar.com
bilgipinari.org
four-am.com
indiarepublicday.com
inquick-enbooks.com
iracmpi.com
kakaschoenen.com
lsm99flash.com
nana1255.com
ngen-niagara.com
technwzs.com
virtualonlinecasino1345.com
wallpapertop.net
nova-click.com
abeautifulcrazylife.com
diggmobile.com
denochemexicana.com
eventhalfkg.com
medcon-taiwan.com
life-himawari.com
myriamshomes.com
nightmarevue.com
allstarsru.com
bestofthebuckeyestate.com
bestofthefirststate.com
bestwireless7.com
declarationintermittent.com
findhereall.com
jingyou888.com
lsm99deal.com
lsm99galaxy.com
moozatech.com
nuagh.com
patliyo.com
philomenamagikz.net
rckouba.net
saturnunipessoallda.com
tallahasseefrolics.com
thematurehardcore.net
totalenvironment-inthatquietearth.com
velislavakaymakanova.com
vermontenergetic.com
sizam-design.com
kakakpintar.com
begorgeouslady.com
1800birks4u.com
2wheelstogo.com
6strip4you.com
bigdata-world.net
emailandco.net
gacapal.com
jharpost.com
krishnaastro.com
lsm99credit.com
mascalzonicampani.com
sitemapxml.org
thecityslums.net
topagh.com
flairnetwebdesign.com
bangkaeair.com
beneventocoupon.com
noternet.org
oqtive.com
smilebrightrx.com
decollage-etiquette.com
1millionbestdownloads.com
7658.info
bidbass.com
devlopworldtech.com
digitalmarketingrajkot.com
fluginfo.net
naqlafshk.com
passion-decouverte.com
playsirius.com
spacceleratorintl.com
stikyballs.com
top10way.com
yokidsyogurt.com
zszyhl.com
16firthcrescent.com
abogadolaboralistamd.com
apk2wap.com
aromacremeria.com
banparacard.com
bosmanraws.com
businessproviderblog.com
caltonosa.com
calvaryrevivalchurch.org
chastenedsoulwithabrokenheart.com
cheminotsgardcevennes.com
cooksspot.com
cqxzpt.com
deesywig.com
deltacartoonmaps.com
despixelsetdeshommes.com
duocoracaobrasileiro.com
fareshopbd.com
goodpainspills.com
kobisitecdn.com
makaigoods.com
mgs1454.com
piccadillyresidences.com
radiolaondafresca.com
rubendorf.com
searchengineimprov.com
sellmyhrvahome.com
shugahouseessentials.com
sonihullquad.com
subtractkilos.com
valeriekelmansky.com
vipasdigitalmarketing.com
voolivrerj.com
zeelonggroup.com
1015southrockhill.com
10x10b.com
111-online-casinos.com
191cb.com
3665arpentunitd.com
aitesonics.com
bag-shokunin.com
brightotech.com
communication-digitale-services.com
covoakland.org
dariaprimapack.com
freefortniteaccountss.com
gatebizglobal.com
global1entertainmentnews.com
greatytene.com
hiroshiwakita.com
iktodaypk.com
jahatsakong.com
meadowbrookgolfgroup.com
newsbharati.net
platinumstudiosdesign.com
slotxogamesplay.com
strikestaruk.com
trucosdefortnite.com
ufabetrune.com
weddedtowhitmore.com
12940brycecanyonunitb.com
1311dietrichoaks.com
2monarchtraceunit303.com
601legendhill.com
850elaine.com
adieusolasomade.com
andora-ke.com
bestslotxogames.com
cannagomcallen.com
endlesslyhot.com
iestpjva.com
ouqprint.com
pwmaplefest.com
qtylmr.com
rb88betting.com
buscadogues.com
1007macfm.com
born-wild.com
growthinvests.com
promocode-casino.com
proyectogalgoargentina.com
wbthompson-art.com
whitemountainwheels.com
7thavehvl.com
developmethis.com
funkydogbowties.com
travelodgegrandjunction.com
gao-town.com
globalmarketsuite.com
blogshippo.com
hdbka.com
proboards67.com
outletonline-michaelkors.com
kalkis-research.com
thuthuatit.net
buckcash.com
hollistercanada.com
docterror.com
asadart.com
vmayke.org
erwincomputers.com
dirimart.org
okkii.com
loteriasdecehegin.com
mountanalog.com
healingtaobritain.com
ttxmonitor.com
bamthemes.com
nwordpress.com
11bolabonanza.com
avgo.top