Download MendeleyPanDDA analysis group deposition
Newman, J.A., Katis, V.L., Gavard, A.E., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.To be published.
5QSQ
PanDDA analysis group deposition -- Crystal Structure of human STAG1 in complex with Z396380540
- PDB DOI: https://doi.org/10.2210/pdb5QSQ/pdb
- Deposition Group: G_1002083 (changed state) ExploreG_1002083
- Classification: TRANSCRIPTION
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2019-05-25 Released: 2019-08-21
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.48 ?
- R-Value Free: 0.289
- R-Value Work: 0.225
- R-Value Observed: 0.229
This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Cohesin subunit SA-1 | 459 | Homo sapiens | Mutation(s): 0 Gene Names: STAG1, SA1, SCC3 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8WVM7 (Homo sapiens) Explore Q8WVM7 Go to UniProtKB: Q8WVM7 | |||||
PHAROS: Q8WVM7 GTEx: ENSG00000118007 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8WVM7 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| HR5 (Subject of Investigation/LOI) Query on HR5 | C [auth A], D [auth B] | ~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide C11 H17 N3 O WFWUJGIABNGBBR-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.48 ?
- R-Value Free: 0.289
- R-Value Work: 0.225
- R-Value Observed: 0.229
- Space Group: P 21 21 2
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 155.168 | ¦Á = 90 |
| b = 167.216 | ¦Â = 90 |
| c = 47.617 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| Aimless | data scaling |
| PDB_EXTRACT | data extraction |
| XDS | data reduction |
| REFMAC | phasing |
Entry History
Deposition Data
- Released Date: 2019-08-21 Deposition Author(s): Newman, J.A., Katis, V.L., Gavard, A.E., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Gileadi, O.
Revision History (Full details and data files)
- Version 1.0: 2019-08-21
Type: Initial release - Version 1.1: 2024-03-06
Changes: Data collection, Database references
