Download MendeleyCrystal structure of the WDR domain of WDR91 in complex with DR3634
Zeng, H., Ahmad, H., Dong, A., Seitova, A., Owen, D., Arrowsmith, C.H., Edwards, A.M., Halabelian, L., Structural Genomics Consortium (SGC)To be published.
9MK7
Crystal structure of the WDR domain of WDR91 in complex with DR3634
- PDB DOI: https://doi.org/10.2210/pdb9MK7/pdb
- Classification: TRANSPORT PROTEIN
- Organism(s): Homo sapiens
- Expression System: Spodoptera frugiperda
- Mutation(s): No
- Deposited: 2024-12-16 Released: 2025-02-26
- Funding Organization(s): Other private
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.31 ?
- R-Value Free: 0.238 (Depositor), 0.237 (DCC)
- R-Value Work: 0.200 (Depositor), 0.206 (DCC)
- R-Value Observed: 0.202 (Depositor)
Starting Model: experimental
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wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| WD repeat-containing protein 91 | 374 | Homo sapiens | Mutation(s): 0 Gene Names: WDR91, HSPC049 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for A4D1P6 (Homo sapiens) Explore A4D1P6 Go to UniProtKB: A4D1P6 | |||||
PHAROS: A4D1P6 GTEx: ENSG00000105875 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | A4D1P6 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| A1BLV (Subject of Investigation/LOI) Query on A1BLV | B [auth A] | (1R)-1-({(6M)-2-(methylamino)-6-[3-(pyrrolidin-1-yl)phenyl]pyrimidin-4-yl}amino)-2,3-dihydro-1H-indene-4-carbonitrile C25 H26 N6 AAOXHEZQAFYPKY-JOCHJYFZSA-N |  | ||
| UNX Query on UNX | C [auth A] | UNKNOWN ATOM OR ION X |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.31 ?
- R-Value Free: 0.238 (Depositor), 0.237 (DCC)
- R-Value Work: 0.200 (Depositor), 0.206 (DCC)
- R-Value Observed: 0.202 (Depositor)
Space Group: C 2 2 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 79.201 | ¦Á = 90 |
| b = 132.236 | ¦Â = 90 |
| c = 118.291 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| HKL-3000 | data scaling |
| PHASER | phasing |
| HKL-3000 | data reduction |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-02-26 Deposition Author(s): Zeng, H., Ahmad, H., Dong, A., Seitova, A., Owen, D., Arrowsmith, C.H., Edwards, A.M., Halabelian, L., Structural Genomics Consortium (SGC)
| Funding Organization | Location | Grant Number |
|---|---|---|
| Other private | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-02-26
Type: Initial release
