3GHC

Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-amino-4-oxo-5-substituted-6-thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agenst

Changes made to a PDB entry after its initial release are considered to be either ��major�� or ��minor��. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.

Version Number	Version Date	Version Type/Reason	Version Change	Revised CIF Category
1.0	2009-09-22	Initial release
1.1	2011-07-13		Version format compliance
1.2	2021-10-20		Database references, Derived calculations	database_2, struct_ref_seq_dif, struct_site
1.3	2023-09-06		Data collection, Refinement description	chem_comp_atom, chem_comp_bond, pdbx_initial_refinement_model	Download

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3GHC

Design, Synthesis, and X-ray Crystal Structure of Classical and Nonclassical 2-amino-4-oxo-5-substituted-6-thieno[2,3-d]pyrimidines as dual thymidylate synthase and dihydrofolate reductase inhibitors and as potential antitumor agenst