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3QFL
Coiled-Coil Domain-Dependent Homodimerization of Intracellular MLA Immune Receptors Defines a Minimal Functional Module for Triggering Cell Death
External Resource: Annotation
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Domain Annotation: ECOD Classification
ECOD Database Homepage
Chains
Family Name
Domain Identifier
Architecture
Possible Homology
Homology
Topology
Family
Provenance Source (Version)
A
RX-CC_like
e3qflA1
A: alpha duplicates or obligate multimers
X: EspA/CesA-like
H: EspA chaperone CesA (From Topology)
T: EspA chaperone CesA
F: RX-CC_like
ECOD (1.6)
Domain Annotation: CATH
CATH Database Homepage
Chain
Domain
Class
Architecture
Topology
Homology
Provenance Source (Version)
A
1.20.5.4130
Mainly Alpha
Up-down Bundle
Single alpha-helices involved in coiled-coils or other helix-helix interfaces
CATH (4.3.0)
Protein Family Annotation
Pfam Database Homepage
Chains
Accession
Name
Description
Comments
Source
A
PF18052
Rx N-terminal domain (Rx_N)
Rx N-terminal domain
This entry represents the N-terminal domain found in many plant resistance proteins [1]. This domain has been predicted to be a coiled-coil, however the structure shows that it adopts a four helical bundle fold [1].
Domain
Gene Ontology: Gene Product Annotation
Gene Ontology Database Homepage
Chains
Polymer
Molecular Function
Biological Process
Cellular Component
A
MLA10
binding
adenyl ribonucleotide binding
nucleotide binding
purine ribonucleotide binding
nucleoside phosphate binding
ion binding
ADP binding
purine nucleotide binding
organic cyclic compound binding
anion binding
adenyl nucleotide binding
heterocyclic compound binding
carbohydrate derivative binding
ribonucleotide binding
binding
adenyl ribonucleotide binding
nucleotide binding
purine ribonucleotide binding
nucleoside phosphate binding
ion binding
ADP binding
purine nucleotide binding
organic cyclic compound binding
anion binding
adenyl nucleotide binding
heterocyclic compound binding
carbohydrate derivative binding
ribonucleotide binding
small molecule binding
Less
biological process involved in interspecies interaction between organisms
response to stimulus
response to other organism
defense response
defense response to other organism
response to stress
response to external stimulus
response to external biotic stimulus
response to biotic stimulus
-
InterPro: Protein Family Classification
InterPro Database Homepage
Chains
Accession
Name
Type
A
IPR041118
Disease resistance, N-terminal
Domain
A
IPR032675
Leucine-rich repeat domain superfamily
Homologous Superfamily
A
IPR042197
Apoptotic protease-activating factors, helical domain
Homologous Superfamily
A
IPR044974
Disease resistance protein, plants
Family
A
IPR036388
Winged helix-like DNA-binding domain superfamily
Homologous Superfamily
A
IPR002182
NB-ARC
Domain
A
IPR038005
Virus X resistance protein-like, coiled-coil domain
Domain
A
IPR027417
P-loop containing nucleoside triphosphate hydrolase
Homologous Superfamily
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