Annotations: 8Y8V

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Aquaporin-like	8098104	3000508	SCOP2B (2022-06-29)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Green fluorescent protein,Aquaporin-7	glycerol channel activity passive transmembrane transporter activity channel activity glycerol transmembrane transporter activity transporter activity polyol transmembrane transporter activity carbohydrate transmembrane transporter activity transmembrane transporter activity urea transmembrane transporter activity amide transmembrane transporter activity water transmembrane transporter activity inorganic molecular entity transmembrane transporter activity water channel activity	bioluminescence metabolic process cellular process generation of precursor metabolites and energy transmembrane transport glycerol transmembrane transport localization transport polyol transmembrane transport carbohydrate transport organic hydroxy compound transport establishment of localization carbohydrate transmembrane transport fluid transport bioluminescence metabolic process cellular process generation of precursor metabolites and energy transmembrane transport glycerol transmembrane transport localization transport polyol transmembrane transport carbohydrate transport organic hydroxy compound transport establishment of localization carbohydrate transmembrane transport fluid transport water transport	membrane-bounded organelle intracellular anatomical structure membrane intracellular vesicle intracellular membrane-bounded organelle intracellular organelle cytoplasmic vesicle membrane cellular anatomical structure vesicle membrane cytoplasmic vesicle organelle cytoplasm vesicle organelle membrane membrane-bounded organelle intracellular anatomical structure membrane intracellular vesicle intracellular membrane-bounded organelle intracellular organelle cytoplasmic vesicle membrane cellular anatomical structure vesicle membrane cytoplasmic vesicle organelle cytoplasm vesicle organelle membrane cell-cell junction anchoring junction cell junction lipid droplet membraneless organelle intracellular membraneless organelle cell periphery plasma membrane basal part of cell basal plasma membrane plasma membrane region basolateral plasma membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR000786	Green fluorescent protein, GFP	Family
A	IPR011584	Green fluorescent protein-related	Family
A	IPR009017	Green fluorescent protein	Homologous Superfamily
A	IPR050363	Major Intrinsic Protein/Aquaporin	Family
A	IPR023271	Aquaporin-like	Homologous Superfamily
A	IPR000425	Major intrinsic protein	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: O14520	obesity disorder Liver Cirrhosis, Experimental intellectual disability psoriasis lung adenocarcinoma

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A	PDBTM	Annotated as membrane protein by PDBTM

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.