9NJK | pdb_00009njk

The Cryo-EM structure of the yeast Rad51-ssDNA nucleoprotein filament ADP bound state

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A [auth D]	SCOP2B Superfamily	RecA-like P-loop NTPases	8056639	3002019	SCOP2B (2022-06-29)
A [auth D]	SCOP2B Superfamily	Helix-hairpin-helix tandem	8056637	3000163	SCOP2B (2022-06-29)
B [auth C]	SCOP2B Superfamily	RecA-like P-loop NTPases	8056639	3002019	SCOP2B (2022-06-29)
B [auth C]	SCOP2B Superfamily	Helix-hairpin-helix tandem	8056637	3000163	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	Helix-hairpin-helix tandem	8056637	3000163	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	RecA-like P-loop NTPases	8056639	3002019	SCOP2B (2022-06-29)
D [auth F]	SCOP2B Superfamily	RecA-like P-loop NTPases	8056639	3002019	SCOP2B (2022-06-29)
D [auth F]	SCOP2B Superfamily	Helix-hairpin-helix tandem	8056637	3000163	SCOP2B (2022-06-29)
F [auth A]	SCOP2B Superfamily	Helix-hairpin-helix tandem	8056637	3000163	SCOP2B (2022-06-29)
F [auth A]	SCOP2B Superfamily	RecA-like P-loop NTPases	8056639	3002019	SCOP2B (2022-06-29)
E [auth B]	SCOP2B Superfamily	RecA-like P-loop NTPases	8056639	3002019	SCOP2B (2022-06-29)
E [auth B]	SCOP2B Superfamily	Helix-hairpin-helix tandem	8056637	3000163	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	PF08423	Rad51 (Rad51)	Rad51	Rad51 is a DNA repair and recombination protein and is a homologue of the bacterial ATPase RecA protein.	Domain
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	PF14520	Helix-hairpin-helix domain (HHH_5)	Helix-hairpin-helix domain		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	DNA repair protein RAD51	ATP-dependent activity, acting on DNA catalytic activity, acting on DNA catalytic activity, acting on a nucleic acid catalytic activity ATP-dependent activity DNA strand exchange activity DNA damage sensor activity molecular sensor activity ATP-dependent DNA damage sensor activity molecular function regulator activity binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding ATP-dependent activity, acting on DNA catalytic activity, acting on DNA catalytic activity, acting on a nucleic acid catalytic activity ATP-dependent activity DNA strand exchange activity DNA damage sensor activity molecular sensor activity ATP-dependent DNA damage sensor activity molecular function regulator activity binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding DNA binding nucleic acid binding double-stranded DNA binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides identical protein binding protein binding single-stranded DNA binding	sexual reproduction reproductive process meiotic cell cycle chromosome organization meiotic cell cycle process cellular component organization chromosome organization involved in meiotic cell cycle organelle organization cellular process cellular component organization or biogenesis cell cycle cell cycle process homologous recombination nucleobase-containing compound metabolic process sexual reproduction reproductive process meiotic cell cycle chromosome organization meiotic cell cycle process cellular component organization chromosome organization involved in meiotic cell cycle organelle organization cellular process cellular component organization or biogenesis cell cycle cell cycle process homologous recombination nucleobase-containing compound metabolic process meiosis I meiotic nuclear division reciprocal homologous recombination DNA recombination organelle fission primary metabolic process DNA metabolic process nucleic acid metabolic process reciprocal meiotic recombination nuclear division meiosis I cell cycle process metabolic process macromolecule metabolic process mitotic recombination telomere organization telomere maintenance telomere maintenance via recombination heteroduplex formation meiotic joint molecule formation DNA strand invasion mitotic DNA replication DNA-templated DNA replication DNA-templated DNA replication maintenance of fidelity nuclear DNA replication cell cycle DNA replication mitotic cell cycle DNA replication mitotic cell cycle process cell cycle DNA replication maintenance of fidelity mitotic recombination-dependent replication fork processing mitotic DNA replication maintenance of fidelity replication fork processing cellular response to stimulus double-strand break repair response to stimulus cellular response to stress DNA damage response response to stress recombinational repair double-strand break repair via homologous recombination DNA repair nucleotide-excision repair mitochondrial genome maintenance mitochondrial DNA metabolic process mitochondrial DNA repair mitochondrion organization cellular component biogenesis protein-DNA complex organization DNA recombinase assembly cellular component assembly protein-containing complex assembly DNA repair complex assembly protein-containing complex organization protein-DNA complex assembly double-strand break repair via synthesis-dependent strand annealing cell cycle G2/M phase transition G2/M transition of mitotic cell cycle cell cycle phase transition mitotic cell cycle phase transition	membrane-bounded organelle condensed nuclear chromosome intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle nuclear chromosome chromosome intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membrane-bounded organelle condensed nuclear chromosome intracellular anatomical structure nucleus membrane-enclosed lumen intracellular membraneless organelle nuclear chromosome chromosome intracellular membrane-bounded organelle intracellular organelle lumen intracellular organelle cellular anatomical structure organelle lumen organelle membraneless organelle condensed chromosome nuclear lumen mitochondrial chromosome mitochondrion nucleoid mitochondrial matrix cytoplasm mitochondrial nucleoid

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	IPR013632	DNA recombination and repair protein Rad51-like, C-terminal	Domain
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	IPR020587	DNA recombination and repair protein RecA, monomer-monomer interface	Domain
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	IPR003593	AAA+ ATPase domain	Domain
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	IPR011941	DNA recombination/repair protein Rad51	Family
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	IPR016467	DNA recombination and repair protein, RecA-like	Family
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	IPR020588	DNA recombination and repair protein RecA-like, ATP-binding domain	Domain
A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], A [auth D], B [auth C], C [auth E], D [auth F], E [auth B], F [auth A]	IPR010995	DNA repair Rad51/transcription factor NusA, alpha-helical	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.