AA9 family lytic polysaccharide monooxygenase cel61A

UniProtKB accession:  G0R6T8

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UniProtKB description:  Lytic polysaccharide monooxygenase (LPMO) that depolymerizes crystalline and amorphous polysaccharides via the oxidation of scissile alpha- or beta-(1-4)-glycosidic bonds, yielding C1 and C4 oxidation products (PubMed:26285758, PubMed:28110665, PubMed:28900033, PubMed:30238672). Catalysis by LPMOs requires the reduction of the active-site copper from Cu(II) to Cu(I) by a reducing agent and H(2)O(2) or O(2) as a cosubstrate (PubMed:28900033, PubMed:32414932, PubMed:34597668). Produces both neutral and oxidized cello-oligosaccharides from cellulose (PubMed:26285758, PubMed:28900033). Acts also on soluble cello-oligosaccharides as short as a tetramer (PubMed:26285758). The oxidative activity displays a synergistic effect capable of boosting endoglucanase activity, and thereby substrate depolymerization of soy cellulose by 27% (PubMed:28110665).