Download MendeleyCryo-EM structure of human HCAR1-Gi complex without ligand (apo state)
Xin, P., Fang, Y.To be published.
9J8Z | pdb_00009j8z
Cryo-EM structure of human HCAR1-Gi complex without ligand (apo state)
- PDB DOI: https://doi.org/10.2210/pdb9J8Z/pdb
- EM Map EMD-61249: EMDB EMDataResource
- Classification: MEMBRANE PROTEIN
- Organism(s): Homo sapiens
- Expression System: Spodoptera frugiperda
- Mutation(s): No
- Deposited: 2024-08-21 Released: 2025-04-02
- Funding Organization(s): National Natural Science Foundation of China (NSFC)
Experimental Data Snapshot
- Method: ELECTRON MICROSCOPY
- Resolution: 3.36 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | A [auth B] | 337 | Homo sapiens | Mutation(s): 0 Gene Names: GNB1 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P62873 (Homo sapiens) Explore P62873 Go to UniProtKB: P62873 | |||||
PHAROS: P62873 GTEx: ENSG00000078369 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P62873 | ||||
Sequence AnnotationsExpand | |||||
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Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Guanine nucleotide-binding protein G(i) subunit alpha-1 | B [auth C] | 351 | Homo sapiens | Mutation(s): 0 Gene Names: GNAI1 EC: 3.6.5 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P63096 (Homo sapiens) Explore P63096 Go to UniProtKB: P63096 | |||||
PHAROS: P63096 GTEx: ENSG00000127955 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P63096 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 3 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | C [auth G] | 56 | Homo sapiens | Mutation(s): 0 Gene Names: GNG2 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P59768 (Homo sapiens) Explore P59768 Go to UniProtKB: P59768 | |||||
PHAROS: P59768 GTEx: ENSG00000186469 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P59768 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 4 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| scFv16 | D [auth S] | 248 | Homo sapiens | Mutation(s): 0 |  |
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 5 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Hydroxycarboxylic acid receptor 1 | E [auth A] | 279 | Homo sapiens | Mutation(s): 0 Gene Names: HCAR1, GPR104, GPR81, HCA1, FKSG80 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9BXC0 (Homo sapiens) Explore Q9BXC0 Go to UniProtKB: Q9BXC0 | |||||
PHAROS: Q9BXC0 GTEx: ENSG00000196917 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9BXC0 | ||||
Sequence AnnotationsExpand | |||||
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Experimental Data & Validation
Experimental Data
- Method: ELECTRON MICROSCOPY
- Resolution: 3.36 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
Entry History & Funding Information
Deposition Data
| Funding Organization | Location | Grant Number |
|---|---|---|
| National Natural Science Foundation of China (NSFC) | China | -- |
Revision History (Full details and data files)
- Version 1.0: 2025-04-02
Type: Initial release
