Crystal Structure of Human DAPK1 Catalytic Subunit Complexed with Compound SRM-26-100
Brunzelle, J.S., Shuvalova, L., Roy, S.M., Watterson, D.M.To be published.
Experimental Data Snapshot
Starting Model: experimental
View more details
Entity ID: 1 | |||||
---|---|---|---|---|---|
Molecule | Chains | Sequence Length | Organism | Details | Image |
Death-associated protein kinase 1 | 293 | Homo sapiens | Mutation(s): 0  Gene Names: DAPK1, DAPK EC: 2.7.11.1 | ![]() | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P53355 (Homo sapiens) Explore P53355  Go to UniProtKB:  P53355 | |||||
PHAROS:  P53355 GTEx:  ENSG00000196730  | |||||
Entity Groups   | |||||
Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
UniProt Group | P53355 | ||||
Sequence AnnotationsExpand | |||||
|
Ligands 2 Unique | |||||
---|---|---|---|---|---|
ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
A1BU8 (Subject of Investigation/LOI) Query on A1BU8 | C [auth A] | 3-(4-methylpiperazin-1-yl)-5-(pyridin-4-yl)pyridazine C14 H17 N5 ABRBOSKOXBQLEU-UHFFFAOYSA-N | |||
SO4 Query on SO4 | B [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |
Length ( ? ) | Angle ( ? ) |
---|---|
a = 46.95 | ¦Á = 90 |
b = 62.52 | ¦Â = 90 |
c = 88.22 | ¦Ă = 90 |
Software Name | Purpose |
---|---|
REFMAC | refinement |
xia2 | data reduction |
Aimless | data scaling |
PHASER | phasing |
Funding Organization | Location | Grant Number |
---|---|---|
Not funded | -- |