2XAD

Crystal structure of deacetylase-teicoplanin complex in biosynthesis pathway of teicoplanin

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PIG-L	e2xadB1	A: a/b three-layered sandwiches	X: LmbE-like (From Topology)	H: LmbE-like (From Topology)	T: LmbE-like	F: PIG-L	ECOD (1.6)
C	PIG-L	e2xadC1	A: a/b three-layered sandwiches	X: LmbE-like (From Topology)	H: LmbE-like (From Topology)	T: LmbE-like	F: PIG-L	ECOD (1.6)
D	PIG-L	e2xadD1	A: a/b three-layered sandwiches	X: LmbE-like (From Topology)	H: LmbE-like (From Topology)	T: LmbE-like	F: PIG-L	ECOD (1.6)
A	PIG-L	e2xadA1	A: a/b three-layered sandwiches	X: LmbE-like (From Topology)	H: LmbE-like (From Topology)	T: LmbE-like	F: PIG-L	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.50.10320	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	LmbE-like	CATH (4.3.0)
C	3.40.50.10320	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	LmbE-like	CATH (4.3.0)
D	3.40.50.10320	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	LmbE-like	CATH (4.3.0)
A	3.40.50.10320	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	LmbE-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF02585	GlcNAc-PI de-N-acetylase (PIG-L)	GlcNAc-PI de-N-acetylase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
E, F, G, H	TEICOPLANIN	-	-	-
A, B, C, D	N-ACYL GLM PEUDO-TEICOPLANIN DEACETYLASE	glycosyltransferase activity transferase activity catalytic activity ligase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides hydrolase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds acyltransferase activity cation binding ion binding binding metal ion binding small molecule binding	glycosyl compound metabolic process glycoside metabolic process carbohydrate derivative metabolic process metabolic process cellular process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR024078	Putative deacetylase LmbE-like domain superfamily	Homologous Superfamily
A, B, C, D	IPR003737	N-acetylglucosaminyl phosphatidylinositol deacetylase-related	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.