Structural basis of gene regulation by protein PII: The crystal complex of PII and PipX from Synechococcus elongatus PCC 7942
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | GlnB-like | 8040085 | 3001165 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | GlnB-like | 8040085 | 3001165 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | GlnB-like | 8040085 | 3001165 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | PipX-like | 8092203 | 3002570 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | PipX-like | 8092203 | 3002570 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | PipX-like | 8092203 | 3002570 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | P-II | e2xg8A1 | A: a+b two layers | X: Alpha-beta plaits | H: GlnB-like (From Topology) | T: GlnB-like | F: P-II | ECOD (1.6) |
B | P-II | e2xg8B1 | A: a+b two layers | X: Alpha-beta plaits | H: GlnB-like (From Topology) | T: GlnB-like | F: P-II | ECOD (1.6) |
C | P-II | e2xg8C1 | A: a+b two layers | X: Alpha-beta plaits | H: GlnB-like (From Topology) | T: GlnB-like | F: P-II | ECOD (1.6) |
D | DUF3539 | e2xg8D1 | A: a+b two layers | X: PipX (From Topology) | H: PipX (From Topology) | T: PipX | F: DUF3539 | ECOD (1.6) |
E | DUF3539 | e2xg8E1 | A: a+b two layers | X: PipX (From Topology) | H: PipX (From Topology) | T: PipX | F: DUF3539 | ECOD (1.6) |
F | DUF3539 | e2xg8F1 | A: a+b two layers | X: PipX (From Topology) | H: PipX (From Topology) | T: PipX | F: DUF3539 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.30.70.120 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | CATH (4.3.0) | |
B | 3.30.70.120 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | CATH (4.3.0) | |
C | 3.30.70.120 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | CATH (4.3.0) | |
D | 2.30.30.660 | Mainly Beta | Roll | SH3 type barrels. | Protein of unknown function (DUF3539) | CATH (4.3.0) |
D | 6.10.250.870 | Special | Helix non-globular | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | CATH (4.3.0) | |
E | 2.30.30.660 | Mainly Beta | Roll | SH3 type barrels. | Protein of unknown function (DUF3539) | CATH (4.3.0) |
E | 6.10.250.870 | Special | Helix non-globular | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00543 | Nitrogen regulatory protein P-II (P-II) | Nitrogen regulatory protein P-II | P-II modulates the activity of glutamine synthetase. It is a tetrameric protein encoded by the glnB gene, a component of the adenylation cascade involved in the regulation of GS activity [1,2]. | Domain | |
PF12058 | PII-interacting protein X (PipX) | PII-interacting protein X | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR015867 | Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal | Homologous Superfamily | |
IPR011322 | Nitrogen regulatory PII-like, alpha/beta | Homologous Superfamily | |
IPR002187 | Nitrogen regulatory protein PII | Family | |
IPR002332 | Nitrogen regulatory protein P-II, urydylation site | PTM | |
IPR017918 | Nitrogen regulatory protein PII, conserved site | Conserved Site | |
IPR021926 | PII-interacting protein X, cyanobacteria | Family |