3GSE

Crystal structure of menaquinone-specific isochorismate synthase from Yersinia pestis CO92

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3gsea_	Alpha and beta proteins (a+b)	ADC synthase	ADC synthase	automated matches	automated matches	(Yersinia pestis ) [TaxId: 632 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	ADC synthase	8080633	4002317	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	ADC synthase	8080634	3001093	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Chorismate_bind	e3gseA1	A: a+b duplicates or obligate multimers	X: ADC synthase (From Topology)	H: ADC synthase (From Topology)	T: ADC synthase	F: Chorismate_bind	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.60.120.10	Alpha Beta	4-Layer Sandwich	Anthranilate synthase	Anthranilate synthase	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00425	chorismate binding enzyme (Chorismate_bind)	chorismate binding enzyme	This family includes the catalytic regions of the chorismate binding enzymes anthranilate synthase, isochorismate synthase, aminodeoxychorismate synthase and para-aminobenzoate synthase.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Menaquinone-specific isochorismate synthase	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding isomerase activity isochorismate synthase activity intramolecular hydroxytransferase activity catalytic activity intramolecular transferase activity	biosynthetic process small molecule biosynthetic process ketone metabolic process menaquinone metabolic process metabolic process cellular process small molecule metabolic process menaquinone biosynthetic process ketone biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR015890	Chorismate-utilising enzyme, C-terminal	Domain
A	IPR044250	Isochorismate synthase MenF-like	Family
A	IPR004561	Isochorismate synthase	Family
A	IPR005801	ADC synthase	Homologous Superfamily
A	IPR034681	Isochorismate synthase MenF	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.