3I4X

Crystal structure of the dimethylallyl tryptophan synthase FgaPT2 from Aspergillus fumigatus in complex with Trp and DMSPP

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Prenyltransferase-like	8053362	3001496	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Prenyltransferase-like	8053362	3001496	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Trp_DMAT	e3i4xB1	A: a+b duplicates or obligate multimers	X: Prenyltransferase-like (From Topology)	H: Prenyltransferase-like (From Topology)	T: Prenyltransferase-like	F: Trp_DMAT	ECOD (1.6)
A	Trp_DMAT	e3i4xA1	A: a+b duplicates or obligate multimers	X: Prenyltransferase-like (From Topology)	H: Prenyltransferase-like (From Topology)	T: Prenyltransferase-like	F: Trp_DMAT	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF11991	Tryptophan dimethylallyltransferase (Trp_DMAT)	Tryptophan dimethylallyltransferase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Tryptophan dimethylallyltransferase	tryptophan dimethylallyltransferase activity transferase activity transferase activity, transferring alkyl or aryl (other than methyl) groups catalytic activity prenyltransferase activity	acetate ester biosynthetic process acetate ester metabolic process alkaloid biosynthetic process indole alkaloid metabolic process alkaloid metabolic process secondary metabolic process terpenoid indole alkaloid biosynthetic process secondary metabolite biosynthetic process biosynthetic process ergot alkaloid metabolic process terpenoid indole alkaloid metabolic process indole alkaloid biosynthetic process metabolic process cellular process acetate ester biosynthetic process acetate ester metabolic process alkaloid biosynthetic process indole alkaloid metabolic process alkaloid metabolic process secondary metabolic process terpenoid indole alkaloid biosynthetic process secondary metabolite biosynthetic process biosynthetic process ergot alkaloid metabolic process terpenoid indole alkaloid metabolic process indole alkaloid biosynthetic process metabolic process cellular process ergot alkaloid biosynthetic process fumigaclavine C biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR017796	Tryptophan dimethylallyltransferase	Family
A, B	IPR017795	Aromatic prenyltransferase, DMATS-type	Family
A, B	IPR033964	Aromatic prenyltransferase	Family
A, B	IPR012148	Aromatic prenyltransferase DMATS-type, fungi	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.