3LPP
Crystal complex of N-terminal sucrase-isomaltase with kotalanol
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
| Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
|---|---|---|---|---|---|
| A | SCOP2B Superfamily | YicI C-terminal domain-like | 8093216 | 3000267 | SCOP2B (2022-06-29) |
| A | SCOP2B Superfamily | (Trans)glycosidases | 8093212 | 3000313 | SCOP2B (2022-06-29) |
| A | SCOP2B Superfamily | Glycosyl hydrolase domain-like | 8093214 | 3001528 | SCOP2B (2022-06-29) |
| A | SCOP2B Superfamily | Galactose mutarotase-like | 8093208 | 3000035 | SCOP2B (2022-06-29) |
| A | SCOP2B Superfamily | Trefoil | 8093210 | 3000849 | SCOP2B (2022-06-29) |
| B | SCOP2 Family | Maltase-glucoamylase N-terminal domain-like | 8046257 | 4004990 | SCOP2 (2022-06-29) |
| B | SCOP2 Family | Trefoil | 8093209 | 4003428 | SCOP2 (2022-06-29) |
| B | SCOP2 Family | YicI catalytic domain-like | 8093211 | 4003298 | SCOP2 (2022-06-29) |
| B | SCOP2 Family | YicI post-catalytic domain-like | 8093213 | 4003233 | SCOP2 (2022-06-29) |
| B | SCOP2 Family | YicI C-terminal domain-like | 8093215 | 4003108 | SCOP2 (2022-06-29) |
| B | SCOP2 Superfamily | Galactose mutarotase-like | 8093208 | 3000035 | SCOP2 (2022-06-29) |
| B | SCOP2 Superfamily | Trefoil | 8093210 | 3000849 | SCOP2 (2022-06-29) |
| B | SCOP2 Superfamily | (Trans)glycosidases | 8093212 | 3000313 | SCOP2 (2022-06-29) |
| B | SCOP2 Superfamily | Glycosyl hydrolase domain-like | 8093214 | 3001528 | SCOP2 (2022-06-29) |
| B | SCOP2 Superfamily | YicI C-terminal domain-like | 8093216 | 3000267 | SCOP2 (2022-06-29) |
| D | SCOP2B Superfamily | Galactose mutarotase-like | 8093208 | 3000035 | SCOP2B (2022-06-29) |
| D | SCOP2B Superfamily | (Trans)glycosidases | 8093212 | 3000313 | SCOP2B (2022-06-29) |
| D | SCOP2B Superfamily | Glycosyl hydrolase domain-like | 8093214 | 3001528 | SCOP2B (2022-06-29) |
| D | SCOP2B Superfamily | Trefoil | 8093210 | 3000849 | SCOP2B (2022-06-29) |
| D | SCOP2B Superfamily | YicI C-terminal domain-like | 8093216 | 3000267 | SCOP2B (2022-06-29) |
| C | SCOP2B Superfamily | YicI C-terminal domain-like | 8093216 | 3000267 | SCOP2B (2022-06-29) |
| C | SCOP2B Superfamily | (Trans)glycosidases | 8093212 | 3000313 | SCOP2B (2022-06-29) |
| C | SCOP2B Superfamily | Trefoil | 8093210 | 3000849 | SCOP2B (2022-06-29) |
| C | SCOP2B Superfamily | Galactose mutarotase-like | 8093208 | 3000035 | SCOP2B (2022-06-29) |
| C | SCOP2B Superfamily | Glycosyl hydrolase domain-like | 8093214 | 3001528 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| A | Glyco_hydro_31_C | e3lppA4 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: Glycosyl hydrolase domain (From Topology) | T: Glycosyl hydrolase domain | F: Glyco_hydro_31_C | ECOD (1.6) |
| A | Gal_mutarotas_2 | e3lppA3 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: supersandwich (From Topology) | T: supersandwich | F: Gal_mutarotas_2 | ECOD (1.6) |
| A | DUF5110_1 | e3lppA5 | A: beta sandwiches | X: Putative glucosidase YicI, C-terminal domain (From Topology) | H: Putative glucosidase YicI, C-terminal domain (From Topology) | T: Putative glucosidase YicI, C-terminal domain | F: DUF5110_1 | ECOD (1.6) |
| A | Glyco_hydro_31_N | e3lppA2 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Glyco_hydro_31_N | ECOD (1.6) |
| A | Trefoil | e3lppA6 | A: few secondary structure elements | X: Trefoil/Plexin domain-like (From Topology) | H: Trefoil/Plexin domain-like (From Topology) | T: Trefoil/Plexin domain-like | F: Trefoil | ECOD (1.6) |
| B | Glyco_hydro_31_C | e3lppB4 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: Glycosyl hydrolase domain (From Topology) | T: Glycosyl hydrolase domain | F: Glyco_hydro_31_C | ECOD (1.6) |
| B | Gal_mutarotas_2 | e3lppB3 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: supersandwich (From Topology) | T: supersandwich | F: Gal_mutarotas_2 | ECOD (1.6) |
| B | DUF5110_1 | e3lppB5 | A: beta sandwiches | X: Putative glucosidase YicI, C-terminal domain (From Topology) | H: Putative glucosidase YicI, C-terminal domain (From Topology) | T: Putative glucosidase YicI, C-terminal domain | F: DUF5110_1 | ECOD (1.6) |
| B | Glyco_hydro_31_N | e3lppB2 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Glyco_hydro_31_N | ECOD (1.6) |
| B | Trefoil | e3lppB6 | A: few secondary structure elements | X: Trefoil/Plexin domain-like (From Topology) | H: Trefoil/Plexin domain-like (From Topology) | T: Trefoil/Plexin domain-like | F: Trefoil | ECOD (1.6) |
| D | Glyco_hydro_31_C | e3lppD11 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: Glycosyl hydrolase domain (From Topology) | T: Glycosyl hydrolase domain | F: Glyco_hydro_31_C | ECOD (1.6) |
| D | Gal_mutarotas_2 | e3lppD10 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: supersandwich (From Topology) | T: supersandwich | F: Gal_mutarotas_2 | ECOD (1.6) |
| D | DUF5110_1 | e3lppD4 | A: beta sandwiches | X: Putative glucosidase YicI, C-terminal domain (From Topology) | H: Putative glucosidase YicI, C-terminal domain (From Topology) | T: Putative glucosidase YicI, C-terminal domain | F: DUF5110_1 | ECOD (1.6) |
| D | Glyco_hydro_31_N | e3lppD9 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Glyco_hydro_31_N | ECOD (1.6) |
| D | Trefoil | e3lppD13 | A: few secondary structure elements | X: Trefoil/Plexin domain-like (From Topology) | H: Trefoil/Plexin domain-like (From Topology) | T: Trefoil/Plexin domain-like | F: Trefoil | ECOD (1.6) |
| C | Glyco_hydro_31_C | e3lppC4 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: Glycosyl hydrolase domain (From Topology) | T: Glycosyl hydrolase domain | F: Glyco_hydro_31_C | ECOD (1.6) |
| C | Gal_mutarotas_2 | e3lppC3 | A: beta sandwiches | X: Glycosyl hydrolase domain-like | H: supersandwich (From Topology) | T: supersandwich | F: Gal_mutarotas_2 | ECOD (1.6) |
| C | DUF5110_1 | e3lppC5 | A: beta sandwiches | X: Putative glucosidase YicI, C-terminal domain (From Topology) | H: Putative glucosidase YicI, C-terminal domain (From Topology) | T: Putative glucosidase YicI, C-terminal domain | F: DUF5110_1 | ECOD (1.6) |
| C | Glyco_hydro_31_N | e3lppC2 | A: a/b barrels | X: TIM beta/alpha-barrel | H: TIM barrels (From Topology) | T: TIM barrels | F: Glyco_hydro_31_N | ECOD (1.6) |
| C | Trefoil | e3lppC6 | A: few secondary structure elements | X: Trefoil/Plexin domain-like (From Topology) | H: Trefoil/Plexin domain-like (From Topology) | T: Trefoil/Plexin domain-like | F: Trefoil | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Protein Family Annotation Pfam Database Homepage
| Chains | Accession | Name | Description | Comments | Source |
|---|---|---|---|---|---|
| PF21365 | Glycosyl hydrolase family 31 C-terminal domain (Glyco_hydro_31_3rd) | Glycosyl hydrolase family 31 C-terminal domain | Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. This entry represents the 3rd beta sandwich domain. | Domain | |
| PF13802 | Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domain (Gal_mutarotas_2) | Glycosyl hydrolase 31 N-terminal galactose mutarotase-like domain | This entry represents the first of three common domains found in Glycosyl hydrolase 31 family proteins. It has a galactose mutarotase superfamily fold. | Domain | |
| PF01055 | Glycosyl hydrolases family 31 TIM-barrel domain (Glyco_hydro_31_2nd) | Glycosyl hydrolases family 31 TIM-barrel domain | Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. This entry corresponds to the second domain of family 31 enzymes and adopts a TIM-barrel fold. | Domain | |
| PF00088 | Trefoil (P-type) domain (Trefoil) | Trefoil (P-type) domain | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
| Chains | Accession | Name | Type |
|---|---|---|---|
| IPR044913 | P-type trefoil domain superfamily | Homologous Superfamily | |
| IPR030459 | Glycosyl hydrolases family 31, conserved site | Conserved Site | |
| IPR000322 | Glycoside hydrolase family 31, TIM barrel domain | Domain | |
| IPR048395 | Glycosyl hydrolase family 31, C-terminal domain | Domain | |
| IPR017853 | Glycoside hydrolase superfamily | Homologous Superfamily | |
| IPR000519 | P-type trefoil domain | Domain | |
| IPR030458 | Glycosyl hydrolases family 31, active site | Active Site | |
| IPR017957 | P-type trefoil, conserved site | Conserved Site | |
| IPR013780 | Glycosyl hydrolase, all-beta | Homologous Superfamily | |
| IPR025887 | Glycoside hydrolase family 31, N-terminal domain | Domain | |
| IPR011013 | Galactose mutarotase-like domain superfamily | Homologous Superfamily |
