3MPZ

Crystal structure of CYTIDINE DEAMINASE from Mycobacterium smegmatis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3mpza1	Alpha and beta proteins (a/b)	Cytidine deaminase-like	Cytidine deaminase-like	automated matches	automated matches	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)
A	d3mpza2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)
B	d3mpzb1	Alpha and beta proteins (a/b)	Cytidine deaminase-like	Cytidine deaminase-like	automated matches	automated matches	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)
B	d3mpzb2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)
D	d3mpzd1	Alpha and beta proteins (a/b)	Cytidine deaminase-like	Cytidine deaminase-like	automated matches	automated matches	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)
D	d3mpzd2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)
C	d3mpzc1	Alpha and beta proteins (a/b)	Cytidine deaminase-like	Cytidine deaminase-like	automated matches	automated matches	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)
C	d3mpzc2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Mycolicibacterium smegmatis MC2 155 ) [TaxId: 246196 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Cytidine deaminase-like	8059097	3001838	SCOP2B (2022-06-29)
B	SCOP2 Family	Cytidine deaminase	8059096	4000870	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Cytidine deaminase-like	8059097	3001838	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	Cytidine deaminase-like	8059097	3001838	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Cytidine deaminase-like	8059097	3001838	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	dCMP_cyt_deam_1	e3mpzA1	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: dCMP_cyt_deam_1	ECOD (1.6)
B	dCMP_cyt_deam_1	e3mpzB1	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: dCMP_cyt_deam_1	ECOD (1.6)
D	dCMP_cyt_deam_1	e3mpzD1	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: dCMP_cyt_deam_1	ECOD (1.6)
C	dCMP_cyt_deam_1	e3mpzC1	A: a+b three layers	X: Cytidine deaminase-like (From Topology)	H: Cytidine deaminase-like (From Topology)	T: Cytidine deaminase-like	F: dCMP_cyt_deam_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase	domain 2	CATH (4.3.0)
B	3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase	domain 2	CATH (4.3.0)
D	3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase	domain 2	CATH (4.3.0)
C	3.40.140.10	Alpha Beta	3-Layer(aba) Sandwich	Cytidine Deaminase	domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF00383	Cytidine and deoxycytidylate deaminase zinc-binding region (dCMP_cyt_deam_1)	Cytidine and deoxycytidylate deaminase zinc-binding region	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Cytidine deaminase	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines cytidine deaminase activity hydrolase activity catalytic activity deaminase activity hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds cation binding ion binding binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR050202	Cytidine and Deoxycytidylate Deaminase	Family
A, B, C, D	IPR002125	Cytidine and deoxycytidylate deaminase domain	Domain
A, B, C, D	IPR016193	Cytidine deaminase-like	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.