4E2Z
X-ray Structure of the H225N mutant of TcaB9, a C-3'-Methyltransferase, in Complex with S-Adenosyl-L-Homocysteine and Sugar Product
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d4e2za_ | Alpha and beta proteins (a/b) | S-adenosyl-L-methionine-dependent methyltransferases | S-adenosyl-L-methionine-dependent methyltransferases | C-3'-methyltransferase-like | TcaB9 | (Micromonospora chalcea ) [TaxId: 1874 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Zinc beta-ribbon | 8051775 | 3001238 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | S-adenosyl-L-methionine-dependent methyltransferases | 8051774 | 3000118 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | CoA-binding Rossmann-fold domain | 8051776 | 3000049 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Methyltransf_14 | e4e2zA3 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: NAD(P)-binding Rossmann-fold domains | F: Methyltransf_14 | ECOD (1.6) |
A | Methyltransf_11_3 | e4e2zA2 | A: a/b three-layered sandwiches | X: Rossmann-like | H: Rossmann-related | T: S-adenosyl-L-methionine-dependent methyltransferases | F: Methyltransf_11_3 | ECOD (1.6) |
A | Methyltransf_13 | e4e2zA1 | A: few secondary structure elements | X: Rubredoxin-like | H: Rubredoxin-related | T: Rubredoxin-related | F: Methyltransf_13 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 6.20.50.110 | Special | Other non-globular | N-terminal domain of TfIIb | Methyltransferase, zinc-binding domain | CATH (4.3.0) |
A | 3.40.50.150 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Vaccinia Virus protein VP39 | CATH (4.3.0) |
A | 6.10.250.3100 | Special | Helix non-globular | Single alpha-helices involved in coiled-coils or other helix-helix interfaces | CATH (4.3.0) | |
A | 3.40.50.720 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | NAD(P)-binding Rossmann-like Domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF08421 | Putative zinc binding domain (Methyltransf_13) | Putative zinc binding domain | This domain is found at the N-terminus of bacterial methyltransferases and contains four conserved cysteines suggesting a potential zinc binding domain. | Domain | |
PF08484 | C-methyltransferase C-terminal domain (Methyltransf_14) | C-methyltransferase C-terminal domain | - | Family | |
PF13489 | Methyltransferase domain (Methyltransf_23) | Methyltransferase domain | This family appears to be a methyltransferase domain. | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
TcaB9 | - |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR013630 | Methyltransferase putative zinc binding domain | Domain | |
IPR029063 | S-adenosyl-L-methionine-dependent methyltransferase superfamily | Homologous Superfamily | |
IPR038576 | Methyltransferase putative zinc binding domain superfamily | Homologous Superfamily | |
IPR013691 | C-methyltransferase | Domain |