Annotations: 4HUL

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Fibronectin type III	8070862	3002063	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	fn3	e4hulB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: fn3	ECOD (1.6)
A	MatE	e4hulA1	A: alpha bundles	X: Type II ABC exporter transmembrane domain fold	H: Multidrug and toxic compound extrusion (MATE) transporter (From Topology)	T: Multidrug and toxic compound extrusion (MATE) transporter	F: MatE	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
B	PF00041	Fibronectin type III domain (fn3)	Fibronectin type III domain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
B	Protein B	cell adhesion molecule binding protein-containing complex binding protein binding binding integrin binding signaling receptor binding structural molecule activity extracellular matrix structural constituent proteoglycan binding carbohydrate derivative binding	cell adhesion cell-matrix adhesion cell-substrate adhesion cellular process cellular component organization cellular component biogenesis cell junction organization cellular component assembly cell junction assembly cell-substrate junction assembly cell-substrate junction organization cellular component organization or biogenesis	-
A	Multidrug efflux protein	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
B	IPR050991	Extracellular Matrix Regulatory Proteins	Family
B	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
B	IPR003961	Fibronectin type III	Domain
B	IPR036116	Fibronectin type III superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.