9BLI | pdb_00009bli

Crystal structure of Actin capping protein in complex with a fragment of Legionella pneumophila RavB

External Resource: Annotation

Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01267	F-actin capping protein alpha subunit (F-actin_cap_A)	F-actin capping protein alpha subunit	-	Family
B	PF01115	F-actin capping protein, beta subunit (F_actin_cap_B)	F-actin capping protein, beta subunit	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	F-actin-capping protein subunit alpha-1	cytoskeletal protein binding actin binding protein-containing complex binding protein binding binding actin filament binding	cellular component organization cellular component biogenesis cell junction organization cellular component assembly cell junction assembly cellular process cellular component organization or biogenesis regulation of cellular process regulation of cellular component size negative regulation of biological process protein-containing complex disassembly regulation of protein-containing complex disassembly actin filament depolymerization regulation of actin filament depolymerization cellular component organization cellular component biogenesis cell junction organization cellular component assembly cell junction assembly cellular process cellular component organization or biogenesis regulation of cellular process regulation of cellular component size negative regulation of biological process protein-containing complex disassembly regulation of protein-containing complex disassembly actin filament depolymerization regulation of actin filament depolymerization actin filament capping actin filament-based process regulation of biological quality negative regulation of supramolecular fiber organization negative regulation of actin filament polymerization cellular component disassembly regulation of biological process barbed-end actin filament capping negative regulation of cellular component organization actin filament organization regulation of organelle organization negative regulation of protein depolymerization negative regulation of protein-containing complex assembly regulation of protein polymerization regulation of supramolecular fiber organization supramolecular fiber organization regulation of cytoskeleton organization regulation of cellular component organization regulation of actin filament-based process regulation of protein-containing complex assembly negative regulation of protein-containing complex disassembly negative regulation of cellular process protein-containing complex assembly negative regulation of protein polymerization regulation of actin filament polymerization actin polymerization or depolymerization protein polymerization regulation of actin filament organization actin cytoskeleton organization actin filament polymerization protein-containing complex organization regulation of protein depolymerization negative regulation of cytoskeleton organization regulation of actin polymerization or depolymerization biological regulation regulation of cellular component biogenesis organelle organization negative regulation of organelle organization regulation of actin filament length regulation of actin cytoskeleton organization negative regulation of actin filament depolymerization protein depolymerization cytoskeleton organization regulation of anatomical structure size	protein-containing complex cellular anatomical structure intracellular anatomical structure WASH complex cytoplasm intracellular membraneless organelle Z disc sarcomere intracellular organelle I band organelle membraneless organelle contractile muscle fiber supramolecular fiber protein-containing complex cellular anatomical structure intracellular anatomical structure WASH complex cytoplasm intracellular membraneless organelle Z disc sarcomere intracellular organelle I band organelle membraneless organelle contractile muscle fiber supramolecular fiber myofibril supramolecular polymer supramolecular complex cytoskeleton F-actin capping protein complex actin cytoskeleton cytosol cell periphery plasma membrane membrane cell cortex cortical cytoskeleton
B	F-actin-capping protein subunit beta isoforms 1 and 2	cytoskeletal protein binding actin binding protein-containing complex binding protein binding binding actin filament binding	lamellipodium assembly plasma membrane bounded cell projection organization cell projection organization plasma membrane bounded cell projection assembly cellular component organization cellular component biogenesis cellular component assembly lamellipodium organization cellular process cellular component organization or biogenesis cell projection assembly developmental process anatomical structure morphogenesis regulation of biological process lamellipodium assembly plasma membrane bounded cell projection organization cell projection organization plasma membrane bounded cell projection assembly cellular component organization cellular component biogenesis cellular component assembly lamellipodium organization cellular process cellular component organization or biogenesis cell projection assembly developmental process anatomical structure morphogenesis regulation of biological process regulation of developmental process anatomical structure development biological regulation cell morphogenesis regulation of cell morphogenesis regulation of anatomical structure morphogenesis filopodium assembly regulation of cellular component organization regulation of cellular process negative regulation of filopodium assembly negative regulation of biological process regulation of filopodium assembly negative regulation of plasma membrane bounded cell projection assembly negative regulation of cellular process negative regulation of cell projection organization negative regulation of cellular component organization regulation of cell projection organization regulation of cell projection assembly regulation of cellular component biogenesis regulation of plasma membrane bounded cell projection assembly regulation of plasma membrane bounded cell projection organization organelle organization cytoskeleton organization regulation of lamellipodium assembly regulation of lamellipodium organization regulation of cellular component size protein-containing complex disassembly regulation of protein-containing complex disassembly actin filament depolymerization regulation of actin filament depolymerization actin filament capping actin filament-based process regulation of biological quality negative regulation of supramolecular fiber organization negative regulation of actin filament polymerization cellular component disassembly barbed-end actin filament capping actin filament organization regulation of organelle organization negative regulation of protein depolymerization negative regulation of protein-containing complex assembly regulation of protein polymerization regulation of supramolecular fiber organization supramolecular fiber organization regulation of cytoskeleton organization regulation of actin filament-based process regulation of protein-containing complex assembly negative regulation of protein-containing complex disassembly protein-containing complex assembly negative regulation of protein polymerization regulation of actin filament polymerization actin polymerization or depolymerization protein polymerization regulation of actin filament organization actin cytoskeleton organization actin filament polymerization protein-containing complex organization regulation of protein depolymerization negative regulation of cytoskeleton organization regulation of actin polymerization or depolymerization negative regulation of organelle organization regulation of actin filament length regulation of actin cytoskeleton organization negative regulation of actin filament depolymerization protein depolymerization regulation of anatomical structure size	cell projection cellular anatomical structure cell leading edge plasma membrane bounded cell projection lamellipodium protein-containing complex intracellular anatomical structure WASH complex cytoplasm membrane intracellular membraneless organelle Z disc sarcomere intracellular organelle cell projection cellular anatomical structure cell leading edge plasma membrane bounded cell projection lamellipodium protein-containing complex intracellular anatomical structure WASH complex cytoplasm membrane intracellular membraneless organelle Z disc sarcomere intracellular organelle I band organelle membraneless organelle contractile muscle fiber supramolecular fiber myofibril supramolecular polymer supramolecular complex cytosol cluster of actin-based cell projections brush border sperm head-tail coupling apparatus neuron to neuron synapse synapse cell junction hippocampal mossy fiber to CA3 synapse cytoskeleton F-actin capping protein complex actin cytoskeleton postsynaptic density postsynapse postsynaptic specialization asymmetric synapse Schaffer collateral - CA1 synapse cell cortex cortical cytoskeleton cell periphery
C	Integrase	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR002189	F-actin-capping protein subunit alpha	Family
A	IPR042489	F-actin capping protein, alpha subunit, domain 1	Homologous Superfamily
A	IPR037282	F-actin-capping protein subunit alpha/beta	Homologous Superfamily
A	IPR017865	F-actin capping protein, alpha subunit, conserved site	Conserved Site
A	IPR042276	F-actin-capping protein subunit alpha/beta, domain 2	Homologous Superfamily
B	IPR001698	F-actin-capping protein subunit beta	Family
B	IPR019771	F-actin capping protein, beta subunit, conserved site	Conserved Site
B	IPR043175	F-actin-capping protein subunit beta, N-terminal domain	Homologous Superfamily
B	IPR037282	F-actin-capping protein subunit alpha/beta	Homologous Superfamily
B	IPR042276	F-actin-capping protein subunit alpha/beta, domain 2	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.