9F5Z | pdb_00009f5z

Structure of the Chlamydomonas reinhardtii respiratory complex III from respiratory supercomplex

External Resource: Annotation

Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth 1A], B [auth 1B]	PF00032	Cytochrome b(C-terminal)/b6/petD (Cytochrom_B_C)	Cytochrome b(C-terminal)/b6/petD		Domain
A [auth 1A], B [auth 1B]	PF00033	Cytochrome b/b6/petB (Cytochrome_B)	Cytochrome b/b6/petB		Domain
R [auth 1R], T [auth 1T]	PF02271	Ubiquinol-cytochrome C reductase complex 14kD subunit (UCR_14kD)	Ubiquinol-cytochrome C reductase complex 14kD subunit	-	Family
C [auth 1C], D [auth 1D]	PF02921	Ubiquinol cytochrome reductase transmembrane region (UCR_TM)	Ubiquinol cytochrome reductase transmembrane region	-	Family
C [auth 1C], D [auth 1D]	PF00355	Rieske [2Fe-2S] domain (Rieske)	Rieske [2Fe-2S] domain	The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in ...	The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in this motif form a disulphide bridge, which stabilises the protein [4].	Domain
E [auth 1E], F [auth 1F]	PF02167	Cytochrome C1 family (Cytochrom_C1)	Cytochrome C1 family	-	Family
G [auth 1G], H [auth 1H]	PF05365	Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like (UCR_UQCRX_QCR9)	Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like	-	Family
I [auth 1I], J [auth 1J]	PF02320	Ubiquinol-cytochrome C reductase hinge protein (UCR_hinge)	Ubiquinol-cytochrome C reductase hinge protein	The ubiquinol-cytochrome C reductase complex (cytochrome bc1 complex) is a respiratory multienzyme complex [1]. This Pfam family represents the 'hinge' protein of the complex which is thought to mediate formation of the cytochrome c1 and cytochrome c ...	The ubiquinol-cytochrome C reductase complex (cytochrome bc1 complex) is a respiratory multienzyme complex [1]. This Pfam family represents the 'hinge' protein of the complex which is thought to mediate formation of the cytochrome c1 and cytochrome c complex.	Domain
K [auth 1K], L [auth 1L]	PF10890	Cytochrome b-c1 complex subunit 8 (Cyt_b-c1_8)	Cytochrome b-c1 complex subunit 8	-	Family
M [auth 1M], N [auth 1N]	PF05193	Peptidase M16 inactive domain (Peptidase_M16_C)	Peptidase M16 inactive domain	Peptidase M16 consists of two structurally related domains. One is the active peptidase, whereas the other is inactive. The two domains hold the substrate like a clamp [1].	Domain
M [auth 1M], N [auth 1N]	PF00675	Insulinase (Peptidase family M16) (Peptidase_M16)	Insulinase (Peptidase family M16)	-	Family
Q [auth 1Q], S [auth 1S]	PF05193	Peptidase M16 inactive domain (Peptidase_M16_C)	Peptidase M16 inactive domain	Peptidase M16 consists of two structurally related domains. One is the active peptidase, whereas the other is inactive. The two domains hold the substrate like a clamp [1].	Domain
Q [auth 1Q], S [auth 1S]	PF00675	Insulinase (Peptidase family M16) (Peptidase_M16)	Insulinase (Peptidase family M16)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth 1A], B [auth 1B]	Cytochrome b	monoatomic cation transmembrane transporter activity proton transmembrane transporter activity oxidoreductase activity, acting on diphenols and related substances as donors primary active transmembrane transporter activity oxidoreductase activity electron transfer activity active monoatomic ion transmembrane transporter activity oxidoreduction-driven active transmembrane transporter activity active transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity ubiquinol-cytochrome-c reductase activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity oxidoreductase activity, acting on diphenols and related substances as donors primary active transmembrane transporter activity oxidoreductase activity electron transfer activity active monoatomic ion transmembrane transporter activity oxidoreduction-driven active transmembrane transporter activity active transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity ubiquinol-cytochrome-c reductase activity catalytic activity transmembrane transporter activity cation binding ion binding binding metal ion binding small molecule binding	cellular respiration energy derivation by oxidation of organic compounds respiratory electron transport chain electron transport chain metabolic process cellular process generation of precursor metabolites and energy	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm organelle membrane respiratory chain complex protein-containing complex catalytic complex cytochrome complex membrane protein complex transporter complex respiratory chain complex III transmembrane transporter complex oxidoreductase complex
R [auth 1R], T [auth 1T]	Cytochrome b-c1 complex subunit 7	-	aerobic respiration cellular respiration aerobic electron transport chain oxidative phosphorylation energy derivation by oxidation of organic compounds ATP synthesis coupled electron transport electron transport chain generation of precursor metabolites and energy mitochondrial electron transport, ubiquinol to cytochrome c respiratory electron transport chain metabolic process cellular process mitochondrial ATP synthesis coupled electron transport	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm organelle membrane respiratory chain complex protein-containing complex catalytic complex cytochrome complex membrane protein complex transporter complex respiratory chain complex III transmembrane transporter complex oxidoreductase complex
C [auth 1C], D [auth 1D]	Cytochrome b-c1 complex subunit Rieske, mitochondrial	oxidoreductase activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity oxidoreductase activity, acting on diphenols and related substances as donors primary active transmembrane transporter activity electron transfer activity active monoatomic ion transmembrane transporter activity oxidoreduction-driven active transmembrane transporter activity active transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity oxidoreductase activity catalytic activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity oxidoreductase activity, acting on diphenols and related substances as donors primary active transmembrane transporter activity electron transfer activity active monoatomic ion transmembrane transporter activity oxidoreduction-driven active transmembrane transporter activity active transmembrane transporter activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity ubiquinol-cytochrome-c reductase activity transmembrane transporter activity iron-sulfur cluster binding 2 iron, 2 sulfur cluster binding binding metal cluster binding small molecule binding cation binding ion binding metal ion binding	aerobic respiration cellular respiration aerobic electron transport chain oxidative phosphorylation energy derivation by oxidation of organic compounds ATP synthesis coupled electron transport electron transport chain generation of precursor metabolites and energy mitochondrial electron transport, ubiquinol to cytochrome c respiratory electron transport chain metabolic process cellular process mitochondrial ATP synthesis coupled electron transport	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm organelle membrane respiratory chain complex protein-containing complex catalytic complex cytochrome complex membrane protein complex transporter complex respiratory chain complex III transmembrane transporter complex oxidoreductase complex
E [auth 1E], F [auth 1F]	Cytochrome c1	oxidoreductase activity catalytic activity binding tetrapyrrole binding heme binding electron transfer activity cation binding ion binding metal ion binding small molecule binding	aerobic respiration cellular respiration aerobic electron transport chain oxidative phosphorylation energy derivation by oxidation of organic compounds ATP synthesis coupled electron transport electron transport chain generation of precursor metabolites and energy mitochondrial electron transport, ubiquinol to cytochrome c respiratory electron transport chain metabolic process cellular process mitochondrial ATP synthesis coupled electron transport	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm organelle membrane respiratory chain complex protein-containing complex catalytic complex cytochrome complex membrane protein complex transporter complex respiratory chain complex III transmembrane transporter complex oxidoreductase complex
G [auth 1G], H [auth 1H]	Complex III subunit 9	oxidoreductase activity catalytic activity	aerobic respiration cellular respiration aerobic electron transport chain oxidative phosphorylation energy derivation by oxidation of organic compounds ATP synthesis coupled electron transport electron transport chain generation of precursor metabolites and energy mitochondrial electron transport, ubiquinol to cytochrome c respiratory electron transport chain metabolic process cellular process mitochondrial ATP synthesis coupled electron transport	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm organelle membrane respiratory chain complex protein-containing complex catalytic complex cytochrome complex membrane protein complex transporter complex respiratory chain complex III transmembrane transporter complex oxidoreductase complex
I [auth 1I], J [auth 1J]	Cytochrome b-c1 complex subunit 6	oxidoreductase activity catalytic activity	aerobic respiration cellular respiration aerobic electron transport chain oxidative phosphorylation energy derivation by oxidation of organic compounds ATP synthesis coupled electron transport electron transport chain generation of precursor metabolites and energy mitochondrial electron transport, ubiquinol to cytochrome c respiratory electron transport chain metabolic process cellular process mitochondrial ATP synthesis coupled electron transport	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm organelle membrane
K [auth 1K], L [auth 1L]	Mitochondrial ubiquinol-cytochrome c oxidoreductase subunit 8	oxidoreductase activity catalytic activity	aerobic respiration cellular respiration aerobic electron transport chain oxidative phosphorylation energy derivation by oxidation of organic compounds ATP synthesis coupled electron transport electron transport chain generation of precursor metabolites and energy mitochondrial electron transport, ubiquinol to cytochrome c respiratory electron transport chain metabolic process cellular process mitochondrial ATP synthesis coupled electron transport	membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm membrane-bounded organelle mitochondrial membrane intracellular anatomical structure organelle inner membrane mitochondrion membrane intracellular membrane-bounded organelle mitochondrial inner membrane intracellular organelle organelle envelope cellular anatomical structure organelle mitochondrial envelope cytoplasm organelle membrane respiratory chain complex protein-containing complex catalytic complex cytochrome complex membrane protein complex transporter complex respiratory chain complex III transmembrane transporter complex oxidoreductase complex
M [auth 1M], N [auth 1N]	MPP-Beta	peptidase activity catalytic activity, acting on a protein metallopeptidase activity hydrolase activity catalytic activity cation binding ion binding binding metal ion binding small molecule binding	-	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle
O [auth 1O], P [auth 1P]	Mitochondrial ubiquinol-cytochrome c oxidoreductase subunit 10	oxidoreductase activity catalytic activity	-	-
Q [auth 1Q], S [auth 1S]	Alpha-MPP	cation binding ion binding binding metal ion binding small molecule binding	-	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth 1A], B [auth 1B]	IPR036150	Cytochrome b/b6, C-terminal domain superfamily	Homologous Superfamily
A [auth 1A], B [auth 1B]	IPR027387	Cytochrome b/b6-like domain superfamily	Homologous Superfamily
A [auth 1A], B [auth 1B]	IPR048260	Cytochrome b/b6, C-terminal domain, eukaryotic/bacterial	Domain
A [auth 1A], B [auth 1B]	IPR016174	Di-haem cytochrome, transmembrane	Homologous Superfamily
A [auth 1A], B [auth 1B]	IPR005798	Cytochrome b/b6, C-terminal	Domain
A [auth 1A], B [auth 1B]	IPR048259	Cytochrome b/b6, N-terminal domain, eukaryotic/bacterial	Domain
A [auth 1A], B [auth 1B]	IPR030689	Cytochrome b	Family
A [auth 1A], B [auth 1B]	IPR005797	Cytochrome b/b6, N-terminal domain	Domain
R [auth 1R], T [auth 1T]	IPR003197	Cytochrome b-c1 complex subunit 7	Family
R [auth 1R], T [auth 1T]	IPR036544	Cytochrome b-c1 complex subunit 7 superfamily	Homologous Superfamily
C [auth 1C], D [auth 1D]	IPR036922	Rieske [2Fe-2S] iron-sulphur domain superfamily	Homologous Superfamily
C [auth 1C], D [auth 1D]	IPR014349	Rieske iron-sulphur protein	Family
C [auth 1C], D [auth 1D]	IPR004192	Cytochrome b-c1 complex subunit Rieske, transmembrane domain	Domain
C [auth 1C], D [auth 1D]	IPR017941	Rieske [2Fe-2S] iron-sulphur domain	Domain
C [auth 1C], D [auth 1D]	IPR005805	Rieske iron-sulphur protein, C-terminal	Domain
C [auth 1C], D [auth 1D]	IPR006317	Ubiquinol-cytochrome c reductase, iron-sulphur subunit	Domain
E [auth 1E], F [auth 1F]	IPR036909	Cytochrome c-like domain superfamily	Homologous Superfamily
E [auth 1E], F [auth 1F]	IPR002326	Cytochrome c1	Family
E [auth 1E], F [auth 1F]	IPR009056	Cytochrome c-like domain	Domain
E [auth 1E], F [auth 1F]	IPR021157	Cytochrome c1, transmembrane anchor, C-terminal	Homologous Superfamily
G [auth 1G], H [auth 1H]	IPR008027	Cytochrome b-c1 complex subunit 9	Family
G [auth 1G], H [auth 1H]	IPR036656	Cytochrome b-c1 complex subunit 9 superfamily	Homologous Superfamily
I [auth 1I], J [auth 1J]	IPR003422	Cytochrome b-c1 complex, subunit 6	Family
I [auth 1I], J [auth 1J]	IPR023184	Ubiquinol-cytochrome C reductase hinge domain	Domain
I [auth 1I], J [auth 1J]	IPR036811	Ubiquinol-cytochrome C reductase hinge domain superfamily	Homologous Superfamily
K [auth 1K], L [auth 1L]	IPR036642	Cytochrome b-c1 complex subunit 8 superfamily	Homologous Superfamily
K [auth 1K], L [auth 1L]	IPR020101	Cytochrome b-c1 complex subunit 8, plants	Family
M [auth 1M], N [auth 1N]	IPR007863	Peptidase M16, C-terminal	Domain
M [auth 1M], N [auth 1N]	IPR011765	Peptidase M16, N-terminal	Domain
M [auth 1M], N [auth 1N]	IPR011249	Metalloenzyme, LuxS/M16 peptidase-like	Homologous Superfamily
M [auth 1M], N [auth 1N]	IPR050361	Mitochondrial Processing Peptidase/Ubiquinol-cytochrome c Reductase Complex	Family
Q [auth 1Q], S [auth 1S]	IPR007863	Peptidase M16, C-terminal	Domain
Q [auth 1Q], S [auth 1S]	IPR011765	Peptidase M16, N-terminal	Domain
Q [auth 1Q], S [auth 1S]	IPR011249	Metalloenzyme, LuxS/M16 peptidase-like	Homologous Superfamily
Q [auth 1Q], S [auth 1S]	IPR050361	Mitochondrial Processing Peptidase/Ubiquinol-cytochrome c Reductase Complex	Family