9GLH | pdb_00009glh

Crystal Structure of UFC1 T106S

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Pharos: Disease Associations

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth AAA]	Ubiquitin-fold modifier-conjugating enzyme 1	aminoacyltransferase activity ubiquitin-like protein transferase activity catalytic activity, acting on a protein acyltransferase activity UFM1 transferase activity transferase activity catalytic activity UFM1 conjugating enzyme activity ubiquitin-like protein conjugating enzyme activity	developmental process multicellular organism development multicellular organismal process head development central nervous system development anatomical structure development animal organ development brain development nervous system development system development regulation of biosynthetic process regulation of biological process regulation of type II interferon production regulation of cellular process developmental process multicellular organism development multicellular organismal process head development central nervous system development anatomical structure development animal organ development brain development nervous system development system development regulation of biosynthetic process regulation of biological process regulation of type II interferon production regulation of cellular process type II interferon production biological regulation regulation of macromolecule metabolic process gene expression macromolecule biosynthetic process regulation of gene expression biosynthetic process cytokine production regulation of cytokine production metabolic process cellular process regulation of macromolecule biosynthetic process regulation of multicellular organismal process macromolecule metabolic process regulation of metabolic process primary metabolic process protein ufmylation macromolecule modification protein metabolic process post-translational protein modification protein modification process protein modification by small protein conjugation protein modification by small protein conjugation or removal catabolic process macroautophagy reticulophagy autophagy process utilizing autophagic mechanism cellular response to stimulus cellular response to stress response to stimulus response to stress response to endoplasmic reticulum stress protein polyufmylation protein K69-linked ufmylation	extracellular exosome membrane-bounded organelle extracellular vesicle cellular anatomical structure extracellular organelle extracellular region organelle extracellular space vesicle extracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth AAA]	IPR016135	Ubiquitin-conjugating enzyme/RWD-like	Homologous Superfamily
A [auth AAA]	IPR014806	Ubiquitin-fold modifier-conjugating enzyme 1	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A [auth AAA]	Pharos: Q9Y3C8	allergic rhinitis ovarian cancer diabetes mellitus plasma cell myeloma lymphoplasmacytic lymphoma

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.