Annotations: 9KH5

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Y+L amino acid transporter 1	L-arginine transmembrane transporter activity L-amino acid transmembrane transporter activity amino acid transmembrane transporter activity organic cation transmembrane transporter activity transporter activity carboxylic acid transmembrane transporter activity organic acid transmembrane transporter activity basic amino acid transmembrane transporter activity transmembrane transporter activity organic anion transmembrane transporter activity	organic acid transmembrane transport organic anion transport nitrogen compound transport carboxylic acid transmembrane transport carboxylic acid transport transport amino acid transmembrane transport L-amino acid transport establishment of localization organic cation transport basic amino acid transmembrane transport L-arginine transmembrane transport organic acid transport transmembrane transport amino acid transport organic acid transmembrane transport organic anion transport nitrogen compound transport carboxylic acid transmembrane transport carboxylic acid transport transport amino acid transmembrane transport L-amino acid transport establishment of localization organic cation transport basic amino acid transmembrane transport L-arginine transmembrane transport organic acid transport transmembrane transport amino acid transport localization basic amino acid transport L-alpha-amino acid transmembrane transport cellular process regulation of biological process regulation of cellular process oxoacid metabolic process biological regulation carboxylic acid metabolic process amino acid metabolic process primary metabolic process organic acid metabolic process alpha-amino acid metabolic process regulation of primary metabolic process arginine metabolic process regulation of small molecule metabolic process regulation of arginine metabolic process regulation of amino acid metabolic process metabolic process small molecule metabolic process regulation of metabolic process neutral amino acid transport L-leucine transport branched-chain amino acid transport	cell periphery cellular anatomical structure plasma membrane membrane basal part of cell basal plasma membrane plasma membrane region basolateral plasma membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR002293	Amino acid/polyamine transporter I	Family
A	IPR050598	Cellular Amino Acid Transporter	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: Q9UM01	lysinuric protein intolerance non-small cell lung carcinoma pancreatic intraductal papillary-mucinous neoplasm prostate carcinoma tuberculosis Amino Acid Metabolism, Inborn Errors cutaneous lupus erythematosus glioblastoma inherited amino acid metabolic disorder lung adenocarcinoma MALT lymphoma osteosarcoma pilocytic astrocytoma Sjogren syndrome ulcerative colitis lysinuric protein intolerance non-small cell lung carcinoma pancreatic intraductal papillary-mucinous neoplasm prostate carcinoma tuberculosis Amino Acid Metabolism, Inborn Errors cutaneous lupus erythematosus glioblastoma inherited amino acid metabolic disorder lung adenocarcinoma MALT lymphoma osteosarcoma pilocytic astrocytoma Sjogren syndrome ulcerative colitis cystic fibrosis head and neck cancer intellectual disability lung cancer malignant glioma nephrosclerosis ovarian cancer plantar fibromatosis subependymal giant cell astrocytoma chronic obstructive pulmonary disease gastric carcinoma interstitial cystitis lung carcinoma

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.