DNA helicase II

UniProtKB accession:  P03018

Grouped By:  Matching UniProtKB accession

UniProtKB description:  A helicase with DNA-dependent ATPase activity (PubMed:8419285). Unwinds DNA duplexes with 3'-5' polarity (PubMed:2170128, PubMed:8419285). Translocates on single-stranded DNA with 3'-5' polarity (PubMed:2942537). Initiates unwinding more efficiently from a nicked substrate than double-stranded DNA (PubMed:2170128, PubMed:8419285). Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair, and probably also in repair of alkylated DNA (Probable) (PubMed:25484163).