Phytase AppA

UniProtKB accession:  P07102

Grouped By:  Matching UniProtKB accession

UniProtKB description:  Catalyzes the hydrolysis of phytate (or myo-inositol hexakisphosphate, an indigestible organic form of phosphorus that is found in many plant tissues) to myo-inositol and inorganic phosphate (PubMed:10696472, PubMed:11035187, PubMed:30712472, PubMed:8387749, Ref.8). Dephosphorylates phytate in a stereospecific way by sequential removal of phosphate groups to produce myo-inositol 2-monophosphate (PubMed:11035187). Also shows phosphoanhydride phosphatase activity and hydrolyzes the distal phosphoryl residues of GTP, the 5'-beta-phosphoryl residue of the regulatory nucleotide ppGpp and tripolyphosphates (PubMed:1429631, PubMed:6282821, PubMed:8407904). Does not split most phosphomonoesters with the exception of the synthetic substrate p-nitrophenyl phosphate (pNPP), 2,3-bisphosphoglycerate and fructose 1,6-bisphosphate (PubMed:10696472, PubMed:1429631, PubMed:6282821, PubMed:8387749, PubMed:8407904, Ref.8).