Download MendeleyThe Crystal Structure of Human spermidine/spermine N1-acetyltransferase
Min, J.R., Wu, H., Zeng, H., Loppnau, P., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N.To be published.
2FXF
Human spermidine/spermine N1-acetyltransferase
- PDB DOI: https://doi.org/10.2210/pdb2FXF/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2006-02-05 Released: 2006-02-14
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 ?
- R-Value Free: 0.250
- R-Value Work: 0.194
- R-Value Observed: 0.196
Starting Model: experimental
View more details
This is version 1.4 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Diamine acetyltransferase 1 | 170 | Homo sapiens | Mutation(s): 0 Gene Names: SAT EC: 2.3.1.57 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P21673 (Homo sapiens) Explore P21673 Go to UniProtKB: P21673 | |||||
PHAROS: P21673 GTEx: ENSG00000130066 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P21673 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 3 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| ACO Query on ACO | G [auth A], J [auth B] | ACETYL COENZYME *A C23 H38 N7 O17 P3 S ZSLZBFCDCINBPY-ZSJPKINUSA-N |  | ||
| ACT Query on ACT | F [auth A] | ACETATE ION C2 H3 O2 QTBSBXVTEAMEQO-UHFFFAOYSA-M |  | ||
| CA Query on CA | C [auth A], D [auth A], E [auth A], H [auth B], I [auth B] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.00 ?
- R-Value Free: 0.250
- R-Value Work: 0.194
- R-Value Observed: 0.196
- Space Group: C 1 2 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 65.631 | ¦Á = 90 |
| b = 66.738 | ¦Â = 94.41 |
| c = 95.66 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| SCALEPACK | data scaling |
| PHASER | phasing |
Entry History
Deposition Data
- Released Date: 2006-02-14 Deposition Author(s): Min, J.R., Wu, H., Zeng, H., Loppnau, P., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Revision History (Full details and data files)
- Version 1.0: 2006-02-14
Type: Initial release - Version 1.1: 2008-05-01
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2017-10-18
Changes: Refinement description - Version 1.4: 2023-08-30
Changes: Data collection, Database references, Derived calculations, Refinement description
