Download MendeleyMolecular basis of sex-steroid translation
Mazumdar, M., Chen, J., Lin, S.-X.To be published.
3KM0
17betaHSD1 in complex with 3beta-diol
- PDB DOI: https://doi.org/10.2210/pdb3KM0/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Homo sapiens
- Mutation(s): No
- Deposited: 2009-11-09 Released: 2010-11-10
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 ?
- R-Value Free: 0.312
- R-Value Work: 0.233
- R-Value Observed: 0.237
This is version 2.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Estradiol 17-beta-dehydrogenase 1 | 327 | Homo sapiens | Mutation(s): 0 EC: 1.1.1.62 (PDB Primary Data), 1.1.1.51 (UniProt) |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P14061 (Homo sapiens) Explore P14061 Go to UniProtKB: P14061 | |||||
PHAROS: P14061 GTEx: ENSG00000108786 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P14061 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| NAP Query on NAP | D [auth A], F [auth B] | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE C21 H28 N7 O17 P3 XJLXINKUBYWONI-NNYOXOHSSA-N |  | ||
| AOM Query on AOM | C [auth A], E [auth B] | 5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL C19 H32 O2 CBMYJHIOYJEBSB-YSZCXEEOSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 ?
- R-Value Free: 0.312
- R-Value Work: 0.233
- R-Value Observed: 0.237
- Space Group: C 1 2 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 154.42 | ¦Á = 90 |
| b = 43.12 | ¦Â = 128.59 |
| c = 121.1 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| CrystalClear | data collection |
| XDS | data scaling |
| REFMAC | refinement |
| XDS | data reduction |
Entry History
Deposition Data
- Released Date: 2010-11-10 Deposition Author(s): Mazumdar, M., Lin, S.-X.
Revision History (Full details and data files)
- Version 1.0: 2010-11-10
Type: Initial release - Version 1.1: 2011-07-13
Changes: Version format compliance - Version 1.2: 2024-02-21
Changes: Data collection, Database references, Derived calculations - Version 2.0: 2024-03-13
Changes: Advisory, Atomic model, Data collection, Derived calculations
