Download MendeleyDomain-Domain Flexibility Leads to Allostery within the Cam Receptor Protein (Crp)
Knapp, J., White, M.A., Lee, J.C.To be published.
3RYP
Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)
- PDB DOI: https://doi.org/10.2210/pdb3RYP/pdb
- Classification: DNA BINDING PROTEIN
- Organism(s): Escherichia coli K-12
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2011-05-11 Released: 2012-05-02
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.60 ?
- R-Value Free: 0.234
- R-Value Work: 0.209
- R-Value Observed: 0.209
Starting Model: experimental
View more details
This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Catabolite gene activator | 210 | Escherichia coli K-12 | Mutation(s): 0 Gene Names: b3357, cap, crp, csm, JW5702 |  | |
UniProt | |||||
Find proteins for P0ACJ8 (Escherichia coli (strain K12)) Explore P0ACJ8 Go to UniProtKB: P0ACJ8 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P0ACJ8 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| CMP Query on CMP | C [auth A], G [auth B] | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE C10 H12 N5 O6 P IVOMOUWHDPKRLL-KQYNXXCUSA-N |  | ||
| GOL Query on GOL | D [auth A], E [auth A], F [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.60 ?
- R-Value Free: 0.234
- R-Value Work: 0.209
- R-Value Observed: 0.209
- Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 46.18 | ¦Á = 90 |
| b = 94.3 | ¦Â = 90 |
| c = 105.61 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| ADSC | data collection |
| AMoRE | phasing |
| CNS | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
Entry History
Deposition Data
- Released Date: 2012-05-02 Deposition Author(s): Knapp, J., White, M.A., Lee, J.C.
Revision History (Full details and data files)
- Version 1.0: 2012-05-02
Type: Initial release - Version 1.1: 2017-11-08
Changes: Refinement description - Version 1.2: 2023-09-13
Changes: Data collection, Database references, Derived calculations, Refinement description
