Download MendeleyHuman nuclear receptor LRH1 bound to phosopholipids and SHP peptide
Gorman, M.A., Parker, M.W., Kusumo, S.To be published.
4ONI
Structure of Human Orphan Receptor LRH1 bound to two bacterial phospholipids
- PDB DOI: https://doi.org/10.2210/pdb4ONI/pdb
- Classification: NUCLEAR PROTEIN
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2014-01-28 Released: 2015-02-11
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 ?
- R-Value Free: 0.202
- R-Value Work: 0.156
- R-Value Observed: 0.158
Starting Model: experimental
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This is version 1.2 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Nuclear receptor subfamily 5 group A member 2 | A, C [auth B] | 253 | Homo sapiens | Mutation(s): 0 Gene Names: NR5A2 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for O00482 (Homo sapiens) Explore O00482 Go to UniProtKB: O00482 | |||||
PHAROS: O00482 GTEx: ENSG00000116833 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | O00482 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Find similar proteins by: Sequence | 3D Structure
Entity ID: 2 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Nuclear receptor subfamily 0 group B member 2 | B [auth C], D | 19 | Homo sapiens | Mutation(s): 0 |  |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q15466 (Homo sapiens) Explore Q15466 Go to UniProtKB: Q15466 | |||||
PHAROS: Q15466 GTEx: ENSG00000131910 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q15466 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| P6L Query on P6L | I [auth B] | (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE C40 H75 O10 P WLVNRDXLPAAELE-GDRYEXQRSA-N |  | ||
| EPH Query on EPH | E [auth A] | L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE C39 H68 N O8 P MABRTXOVHMDVAT-AAEGOEIASA-N |  | ||
| PG4 Query on PG4 | J [auth B] | TETRAETHYLENE GLYCOL C8 H18 O5 UWHCKJMYHZGTIT-UHFFFAOYSA-N |  | ||
| GOL Query on GOL | F [auth A], G [auth A], H [auth A] | GLYCEROL C3 H8 O3 PEDCQBHIVMGVHV-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.80 ?
- R-Value Free: 0.202
- R-Value Work: 0.156
- R-Value Observed: 0.158
- Space Group: P 1 21 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 63.867 | ¦Á = 90 |
| b = 59.856 | ¦Â = 93.86 |
| c = 73.94 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| SCALA | data scaling |
| MOLREP | phasing |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| Blu-Ice | data collection |
| XSCALE | data scaling |
Entry History
Deposition Data
- Released Date: 2015-02-11 Deposition Author(s): Gorman, M.A., Parker, M.W., Kusumo, S.
Revision History (Full details and data files)
- Version 1.0: 2015-02-11
Type: Initial release - Version 1.1: 2017-11-22
Changes: Refinement description - Version 1.2: 2023-11-08
Changes: Data collection, Database references, Derived calculations, Refinement description
