Download MendeleyNON-STEREOSPECIFIC SUBSTRATE CLEAVAGE BY TAGATOSE-BISPHOSPHATE CLASS I ALDOLASE
LowKam, C., Liotard, B., Sygusch, J.To be published.
5F4W
Tagatose-1,6-bisphosphate aldolase from Streptococcus pyogenes in complex with TBP
- PDB DOI: https://doi.org/10.2210/pdb5F4W/pdb
- Classification: LYASE
- Organism(s): Streptococcus pyogenes serotype M1
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2015-12-03 Released: 2017-02-01
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.66 ?
- R-Value Free: 0.206
- R-Value Work: 0.173
- R-Value Observed: 0.174
Starting Model: experimental
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This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Tagatose 1,6-diphosphate aldolase 2 | 327 | Streptococcus pyogenes serotype M1 | Mutation(s): 0 Gene Names: lacD2, lacD.2, SPy_1919, M5005_Spy1635 EC: 4.1.2.40 |  | |
UniProt | |||||
Find proteins for P63705 (Streptococcus pyogenes serotype M1) Explore P63705 Go to UniProtKB: P63705 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P63705 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| P6T Query on P6T | E [auth A] | 1,6-di-O-phosphono-D-tagatose C6 H14 O12 P2 XPYBSIWDXQFNMH-PQLUHFTBSA-N |  | ||
| 13P Query on 13P | G [auth A] | 1,3-DIHYDROXYACETONEPHOSPHATE C3 H7 O6 P GNGACRATGGDKBX-UHFFFAOYSA-N |  | ||
| CA Query on CA | H [auth A], I [auth A], K [auth C], M [auth D] | CALCIUM ION Ca BHPQYMZQTOCNFJ-UHFFFAOYSA-N |  | ||
| CL Query on CL | F [auth A], J [auth B], L [auth C], N [auth D] | CHLORIDE ION Cl VEXZGXHMUGYJMC-UHFFFAOYSA-M |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.66 ?
- R-Value Free: 0.206
- R-Value Work: 0.173
- R-Value Observed: 0.174
- Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 63.955 | ¦Á = 90 |
| b = 107.373 | ¦Â = 90 |
| c = 237.73 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| HKL-2000 | data reduction |
| HKL-2000 | data scaling |
| PHENIX | phasing |
Entry History
Deposition Data
- Released Date: 2017-02-01 Deposition Author(s): LowKam, C.
Revision History (Full details and data files)
- Version 1.0: 2017-02-01
Type: Initial release - Version 1.1: 2023-09-27
Changes: Data collection, Database references, Derived calculations, Refinement description
