Download MendeleyTryptophan Repressor TrpR: A study of ligand binding specificity
Stiel, A.C., Shanmugaratnam, S., Hocker, B.To be published.
6F7F
Tryptophan Repressor TrpR from E.coli with 3-Indolepropionic acid
- PDB DOI: https://doi.org/10.2210/pdb6F7F/pdb
- Classification: TRANSCRIPTION
- Organism(s): Escherichia coli
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2017-12-08 Released: 2019-03-27
- Funding Organization(s): German Research Foundation
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.13 ?
- R-Value Free: 0.229
- R-Value Work: 0.172
- R-Value Observed: 0.175
Starting Model: experimental
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This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Trp operon repressor | A [auth B], B [auth A], C [auth D], D [auth C] | 103 | Escherichia coli | Mutation(s): 0 Gene Names: trpR, rtrY, b4393, JW4356 |  |
UniProt | |||||
Find proteins for P0A881 (Escherichia coli (strain K12)) Explore P0A881 Go to UniProtKB: P0A881 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P0A881 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| IOP Query on IOP | E [auth B], F [auth A], G [auth D], H [auth C] | INDOLYLPROPIONIC ACID C11 H11 N O2 GOLXRNDWAUTYKT-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.13 ?
- R-Value Free: 0.229
- R-Value Work: 0.172
- R-Value Observed: 0.175
- Space Group: P 43
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 81.84 | ¦Á = 90 |
| b = 81.84 | ¦Â = 90 |
| c = 70.57 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| XSCALE | data scaling |
| PHASER | phasing |
| PDB_EXTRACT | data extraction |
Entry History & Funding Information
Deposition Data
- Released Date: 2019-03-27 Deposition Author(s): Stiel, A.C., Shanmugaratnam, S., Hocker, B.
| Funding Organization | Location | Grant Number |
|---|---|---|
| German Research Foundation | Germany | HO 4022/2-3 |
Revision History (Full details and data files)
- Version 1.0: 2019-03-27
Type: Initial release - Version 1.1: 2024-01-17
Changes: Data collection, Database references, Refinement description
