Download MendeleyBlood group synthase AAGlyB in complex with UDP-Gal and cryoprotected with PEG 3350
Rocha, J., Batot, G.O., Palcic, M.M., Breton, C., Royant, A.To be published.
6GX0
Blood group synthase AAGlyB in complex with UDP-Gal and cryoprotected with PEG 3350
- PDB DOI: https://doi.org/10.2210/pdb6GX0/pdb
- Classification: TRANSFERASE
- Organism(s): Homo sapiens
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2018-06-26 Released: 2019-07-10
- Funding Organization(s): French National Research Agency
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.25 ?
- R-Value Free: 0.151
- R-Value Work: 0.122
- R-Value Observed: 0.123
Starting Model: experimental
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This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) | 298 | Homo sapiens | Mutation(s): 1 Gene Names: ABO EC: 2.4.1.40 (UniProt), 2.4.1.37 (UniProt) |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for P16442 (Homo sapiens) Explore P16442 Go to UniProtKB: P16442 | |||||
PHAROS: P16442 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P16442 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 5 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| GDU Query on GDU | C [auth A] | GALACTOSE-URIDINE-5'-DIPHOSPHATE C15 H24 N2 O17 P2 HSCJRCZFDFQWRP-ABVWGUQPSA-N |  | ||
| PEG Query on PEG | G [auth A] | DI(HYDROXYETHYL)ETHER C4 H10 O3 MTHSVFCYNBDYFN-UHFFFAOYSA-N |  | ||
| SO4 Query on SO4 | D [auth A], E [auth A], F [auth A] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| EDO Query on EDO | H [auth A], I [auth A], J [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| MN Query on MN | B [auth A] | MANGANESE (II) ION Mn WAEMQWOKJMHJLA-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.25 ?
- R-Value Free: 0.151
- R-Value Work: 0.122
- R-Value Observed: 0.123
- Space Group: C 2 2 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 52.849 | α = 90 |
| b = 148.92 | β = 90 |
| c = 80.039 | γ = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| XDS | data reduction |
| Aimless | data scaling |
| REFMAC | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2019-07-10 Deposition Author(s): Rocha, J., Royant, A.
| Funding Organization | Location | Grant Number |
|---|---|---|
| French National Research Agency | France | ANR-13-BSV8-0011-02 |
Revision History (Full details and data files)
- Version 1.0: 2019-07-10
Type: Initial release - Version 1.1: 2024-01-17
Changes: Data collection, Database references, Derived calculations, Refinement description
