Download MendeleyPanDDA analysis group deposition
Kim, Y., Marples, P., Fearon, D., von Delft, F., Knapp, S., Kraemer, A., Structural Genomics Consortium (SGC)To be published.
7HLB
PanDDA analysis group deposition -- Crystal Structure of TRIM21 in complex with Z45705015
- PDB DOI: https://doi.org/10.2210/pdb7HLB/pdb
- Deposition Group: G_1002320 (changed state) ExploreG_1002320
- Classification: LIGASE
- Organism(s): Mus musculus
- Expression System: Escherichia coli
- Mutation(s): No
- Deposited: 2024-11-04 Released: 2024-11-27
- Funding Organization(s): European Union (EU)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.21 ?
- R-Value Free: 0.197
- R-Value Work: 0.179
- R-Value Observed: 0.180
Starting Model: experimental
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This is version 1.0 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| E3 ubiquitin-protein ligase TRIM21 | A [auth B] | 188 | Mus musculus | Mutation(s): 0 Gene Names: Trim21, Ro52, Ssa1 EC: 2.3.2.27 |  |
UniProt | |||||
Find proteins for Q62191 (Mus musculus) Explore Q62191 Go to UniProtKB: Q62191 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q62191 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 4 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| EPE Query on EPE | C [auth B] | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID C8 H18 N2 O4 S JKMHFZQWWAIEOD-UHFFFAOYSA-N |  | ||
| S9S (Subject of Investigation/LOI) Query on S9S | B | ~{N}-[2-(4-fluorophenyl)ethyl]methanesulfonamide C9 H12 F N O2 S JZUQJFQXYYHUJT-UHFFFAOYSA-N |  | ||
| SO4 Query on SO4 | E [auth B] | SULFATE ION O4 S QAOWNCQODCNURD-UHFFFAOYSA-L |  | ||
| EDO Query on EDO | D [auth B] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.21 ?
- R-Value Free: 0.197
- R-Value Work: 0.179
- R-Value Observed: 0.180
- Space Group: I 4
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 95.828 | ¦Á = 90 |
| b = 95.828 | ¦Â = 90 |
| c = 45.545 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| REFMAC | refinement |
| Aimless | data scaling |
| XDS | data reduction |
| REFMAC | phasing |
Entry History & Funding Information
Deposition Data
- Released Date: 2024-11-27 Deposition Author(s): Kim, Y., Marples, P., Fearon, D., von Delft, F., Knapp, S., Kraemer, A., Structural Genomics Consortium (SGC)
| Funding Organization | Location | Grant Number |
|---|---|---|
| European Union (EU) | European Union | 875510 |
Revision History (Full details and data files)
- Version 1.0: 2024-11-27
Type: Initial release
