Download MendeleyCrystal structural of methylenetetrahydrofolate reductase from Sphingobium sp. SYK-6
Yu, H.Y., Senda, T.To be published.
7XG9
Crystal structural of methylenetetrahydrofolate reductase from Sphingobium sp. SYK-6
- PDB DOI: https://doi.org/10.2210/pdb7XG9/pdb
- Classification: OXIDOREDUCTASE
- Organism(s): Sphingobium sp. SYK-6
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2022-04-04 Released: 2023-04-12
- Funding Organization(s): Japan Agency for Medical Research and Development (AMED)
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 ?
- R-Value Free: 0.204
- R-Value Work: 0.180
- R-Value Observed: 0.181
This is version 1.1 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| 5,10-methylenetetrahydrofolate reductase | 288 | Sphingobium sp. SYK-6 | Mutation(s): 0 Gene Names: metF, SLG_12750 EC: 1.5.1.20 (PDB Primary Data), 1.5.1.54 (UniProt) |  | |
UniProt | |||||
Find proteins for G2IQS8 (Sphingobium sp. (strain NBRC 103272 / SYK-6)) Explore G2IQS8 Go to UniProtKB: G2IQS8 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | G2IQS8 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 2 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| FAD (Subject of Investigation/LOI) Query on FAD | C [auth A], E [auth B] | FLAVIN-ADENINE DINUCLEOTIDE C27 H33 N9 O15 P2 VWWQXMAJTJZDQX-UYBVJOGSSA-N |  | ||
| PEG Query on PEG | D [auth A], F [auth B] | DI(HYDROXYETHYL)ETHER C4 H10 O3 MTHSVFCYNBDYFN-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 1.50 ?
- R-Value Free: 0.204
- R-Value Work: 0.180
- R-Value Observed: 0.181
- Space Group: P 1 21 1
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 37.056 | ¦Á = 90 |
| b = 168.117 | ¦Â = 105.551 |
| c = 45.424 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| PHENIX | refinement |
| XDS | data reduction |
| Aimless | data scaling |
| CRANK2 | phasing |
Entry History & Funding Information
Deposition Data
| Funding Organization | Location | Grant Number |
|---|---|---|
| Japan Agency for Medical Research and Development (AMED) | Japan | JP21am0101001 |
Revision History (Full details and data files)
- Version 1.0: 2023-04-12
Type: Initial release - Version 1.1: 2024-05-29
Changes: Data collection
