9N80 | pdb_00009n80

Crystal structure of human HRSP12

PDB DOI: https://doi.org/10.2210/pdb9N80/pdb

Classification: RNA BINDING PROTEIN
Organism(s): Homo sapiens
Expression System: Escherichia coli BL21(DE3)
Mutation(s): No

Deposited: 2025-02-07 Released: 2025-03-19
Deposition Author(s): Suma, K., Mugridge, J.S.
Funding Organization(s): National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Experimental Data Snapshot

Method: X-RAY DIFFRACTION
Resolution: 1.39 ?
R-Value Free:
0.217 (Depositor), 0.217 (DCC)
R-Value Work:
0.191 (Depositor), 0.192 (DCC)
R-Value Observed:
0.192 (Depositor)

Starting Model: experimental
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wwPDB Validation 3D Report Full Report

This is version 1.0 of the entry. See complete history.

Literature

Crystal structure of human HRSP12

Suma, K., Jeffrey, S.M.

To be published.

Macromolecule Content

Total Structure Weight: 32.89 kDa
Atom Count: 2,252
Modelled Residue Count: 274
Deposited Residue Count: 306
Unique protein chains: 1

Macromolecules

Find similar proteins by:

(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
2-iminobutanoate/2-iminopropanoate deaminase	A, B	153	Homo sapiens	Mutation(s): 0 Gene Names: RIDA, HRSP12 EC: 3.5.99.10
UniProt & NIH Common Fund Data Resources
Find proteins for P52758 (Homo sapiens) Explore P52758 Go to UniProtKB: P52758
PHAROS: P52758 GTEx: ENSG00000132541
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P52758
Sequence Annotations Expand
Reference Sequence

Experimental Data & Validation

Experimental Data

Method: X-RAY DIFFRACTION
Resolution: 1.39 ?
R-Value Free: 0.217 (Depositor), 0.217 (DCC)
R-Value Work: 0.191 (Depositor), 0.192 (DCC)
R-Value Observed: 0.192 (Depositor)

Space Group: P 2₁ 3

Unit Cell:

Length ( ? )	Angle ( ? )
a = 88.486	α = 90
b = 88.486	β = 90
c = 88.486	γ = 90

Software Package:

Software Name	Purpose
PHENIX	refinement
XDS	data reduction
PHASER	phasing
XDS	data scaling

Structure Validation

View Full Validation Report

Entry History & Funding Information

Deposition Data

Released Date: 2025-03-19

Deposition Author(s):

Funding Organization	Location	Grant Number
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)	United States	R35 GM143000

Revision History (Full details and data files)

Version 1.0: 2025-03-19
Type: Initial release

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.