4XUD

Synthesis and evaluation of heterocyclic catechol mimics as inhibitors of catechol-O-methyltransferase (COMT): Structure with Cmpd32 ([1-(biphenyl-3-yl)-5-hydroxy-4-oxo-1,4-dihydropyridin-3-yl]boronic acid)

Changes made to a PDB entry after its initial release are considered to be either ��major�� or ��minor��. The latest minor version of each major version is available as a file download. More information about the PDB versioning is available.

Version Number	Version Date	Version Type/Reason	Version Change	Revised CIF Category
1.0	2015-04-15	Initial release
1.1	2017-11-22		Derived calculations, Refinement description, Source and taxonomy, Structure summary	entity_src_gen, pdbx_struct_assembly, pdbx_struct_oper_list, software, struct_keywords
1.2	2023-09-27		Data collection, Database references, Refinement description	chem_comp_atom, chem_comp_bond, database_2, pdbx_initial_refinement_model	Download

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.