1GK8

Rubisco from Chlamydomonas reinhardtii

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1gk8a1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	RuBisCo, C-terminal domain	RuBisCo, large subunit, C-terminal domain	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
A	d1gk8a2	Alpha and beta proteins (a+b)	Ferredoxin-like	RuBisCO, large subunit, small (N-terminal) domain	Ribulose 1,5-bisphosphate carboxylase-oxygenase	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
B [auth C]	d1gk8c1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	RuBisCo, C-terminal domain	RuBisCo, large subunit, C-terminal domain	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
B [auth C]	d1gk8c2	Alpha and beta proteins (a+b)	Ferredoxin-like	RuBisCO, large subunit, small (N-terminal) domain	Ribulose 1,5-bisphosphate carboxylase-oxygenase	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
C [auth E]	d1gk8e1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	RuBisCo, C-terminal domain	RuBisCo, large subunit, C-terminal domain	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
C [auth E]	d1gk8e2	Alpha and beta proteins (a+b)	Ferredoxin-like	RuBisCO, large subunit, small (N-terminal) domain	Ribulose 1,5-bisphosphate carboxylase-oxygenase	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
D [auth G]	d1gk8g1	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	RuBisCo, C-terminal domain	RuBisCo, large subunit, C-terminal domain	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
D [auth G]	d1gk8g2	Alpha and beta proteins (a+b)	Ferredoxin-like	RuBisCO, large subunit, small (N-terminal) domain	Ribulose 1,5-bisphosphate carboxylase-oxygenase	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
E [auth I]	d1gk8i_	Alpha and beta proteins (a+b)	RuBisCO, small subunit	RuBisCO, small subunit	RuBisCO, small subunit	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
F [auth K]	d1gk8k_	Alpha and beta proteins (a+b)	RuBisCO, small subunit	RuBisCO, small subunit	RuBisCO, small subunit	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
G [auth M]	d1gk8m_	Alpha and beta proteins (a+b)	RuBisCO, small subunit	RuBisCO, small subunit	RuBisCO, small subunit	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)
H [auth O]	d1gk8o_	Alpha and beta proteins (a+b)	RuBisCO, small subunit	RuBisCO, small subunit	RuBisCO, small subunit	Ribulose 1,5-bisphosphate carboxylase-oxygenase	(Chlamydomonas reinhardtii ) [TaxId: 3055 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	RuBisCo, large subunit, C-terminal domain	8023508	4003287	SCOP2 (2022-06-29)
A	SCOP2 Family	Ribulose 1, 5-bisphosphate carboxylase-oxygenase	8023511	4001311	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	RuBisCo, C-terminal domain	8035888	3000552	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	RuBisCO, large subunit, small (N-terminal) domain	8035891	3001258	SCOP2 (2022-06-29)
B [auth C]	SCOP2B Superfamily	RuBisCo, C-terminal domain	8035888	3000552	SCOP2B (2022-06-29)
B [auth C]	SCOP2B Superfamily	RuBisCO, large subunit, small (N-terminal) domain	8035891	3001258	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	RuBisCo, C-terminal domain	8035888	3000552	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	RuBisCO, large subunit, small (N-terminal) domain	8035891	3001258	SCOP2B (2022-06-29)
D [auth G]	SCOP2B Superfamily	RuBisCo, C-terminal domain	8035888	3000552	SCOP2B (2022-06-29)
D [auth G]	SCOP2B Superfamily	RuBisCO, large subunit, small (N-terminal) domain	8035891	3001258	SCOP2B (2022-06-29)
E [auth I]	SCOP2 Family	RuBisCO, small subunit	8023517	4001455	SCOP2 (2022-06-29)
E [auth I]	SCOP2 Superfamily	RuBisCO, small subunit	8035897	3001622	SCOP2 (2022-06-29)
F [auth K]	SCOP2B Superfamily	RuBisCO, small subunit	8035897	3001622	SCOP2B (2022-06-29)
G [auth M]	SCOP2B Superfamily	RuBisCO, small subunit	8035897	3001622	SCOP2B (2022-06-29)
H [auth O]	SCOP2B Superfamily	RuBisCO, small subunit	8035897	3001622	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	RuBisCO_large_N	e1gk8A1	A: a+b two layers	X: Alpha-beta plaits	H: RuBisCO, large subunit, small (N-terminal) domain (From Topology)	T: RuBisCO, large subunit, small (N-terminal) domain	F: RuBisCO_large_N	ECOD (1.6)
A	RuBisCO_large	e1gk8A2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: RuBisCO_large	ECOD (1.6)
B [auth C]	RuBisCO_large_N	e1gk8C1	A: a+b two layers	X: Alpha-beta plaits	H: RuBisCO, large subunit, small (N-terminal) domain (From Topology)	T: RuBisCO, large subunit, small (N-terminal) domain	F: RuBisCO_large_N	ECOD (1.6)
B [auth C]	RuBisCO_large	e1gk8C2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: RuBisCO_large	ECOD (1.6)
C [auth E]	RuBisCO_large_N	e1gk8E1	A: a+b two layers	X: Alpha-beta plaits	H: RuBisCO, large subunit, small (N-terminal) domain (From Topology)	T: RuBisCO, large subunit, small (N-terminal) domain	F: RuBisCO_large_N	ECOD (1.6)
C [auth E]	RuBisCO_large	e1gk8E2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: RuBisCO_large	ECOD (1.6)
D [auth G]	RuBisCO_large_N	e1gk8G1	A: a+b two layers	X: Alpha-beta plaits	H: RuBisCO, large subunit, small (N-terminal) domain (From Topology)	T: RuBisCO, large subunit, small (N-terminal) domain	F: RuBisCO_large_N	ECOD (1.6)
D [auth G]	RuBisCO_large	e1gk8G2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: RuBisCO_large	ECOD (1.6)
E [auth I]	RuBisCO_small	e1gk8I1	A: a+b two layers	X: Reverse ferredoxin	H: RuBisCO, small subunit (From Topology)	T: RuBisCO, small subunit	F: RuBisCO_small	ECOD (1.6)
F [auth K]	RuBisCO_small	e1gk8K1	A: a+b two layers	X: Reverse ferredoxin	H: RuBisCO, small subunit (From Topology)	T: RuBisCO, small subunit	F: RuBisCO_small	ECOD (1.6)
G [auth M]	RuBisCO_small	e1gk8M1	A: a+b two layers	X: Reverse ferredoxin	H: RuBisCO, small subunit (From Topology)	T: RuBisCO, small subunit	F: RuBisCO_small	ECOD (1.6)
H [auth O]	RuBisCO_small	e1gk8O1	A: a+b two layers	X: Reverse ferredoxin	H: RuBisCO, small subunit (From Topology)	T: RuBisCO, small subunit	F: RuBisCO_small	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.30.70.150	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	RuBisCO large subunit, N-terminal domain	CATH (4.3.0)
A	3.20.20.110	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Ribulose bisphosphate carboxylase, large subunit, C-terminal domain	CATH (4.3.0)
B [auth C]	3.30.70.150	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	RuBisCO large subunit, N-terminal domain	CATH (4.3.0)
B [auth C]	3.20.20.110	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Ribulose bisphosphate carboxylase, large subunit, C-terminal domain	CATH (4.3.0)
C [auth E]	3.30.70.150	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	RuBisCO large subunit, N-terminal domain	CATH (4.3.0)
C [auth E]	3.20.20.110	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Ribulose bisphosphate carboxylase, large subunit, C-terminal domain	CATH (4.3.0)
D [auth G]	3.30.70.150	Alpha Beta	2-Layer Sandwich	Alpha-Beta Plaits	RuBisCO large subunit, N-terminal domain	CATH (4.3.0)
D [auth G]	3.20.20.110	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Ribulose bisphosphate carboxylase, large subunit, C-terminal domain	CATH (4.3.0)
E [auth I]	3.30.190.10	Alpha Beta	2-Layer Sandwich	Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase	Ribulose bisphosphate carboxylase, small subunit	CATH (4.3.0)
F [auth K]	3.30.190.10	Alpha Beta	2-Layer Sandwich	Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase	Ribulose bisphosphate carboxylase, small subunit	CATH (4.3.0)
G [auth M]	3.30.190.10	Alpha Beta	2-Layer Sandwich	Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase	Ribulose bisphosphate carboxylase, small subunit	CATH (4.3.0)
H [auth O]	3.30.190.10	Alpha Beta	2-Layer Sandwich	Ribulose 1,5 Bisphosphate Carboxylase/Oxygenase	Ribulose bisphosphate carboxylase, small subunit	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B [auth C], C [auth E], D [auth G]	PF02788	Ribulose bisphosphate carboxylase large chain, N-terminal domain (RuBisCO_large_N)	Ribulose bisphosphate carboxylase large chain, N-terminal domain	The N-terminal domain of RuBisCO large chain adopts a ferredoxin-like fold.	Domain
A, B [auth C], C [auth E], D [auth G]	PF00016	Ribulose bisphosphate carboxylase large chain, catalytic domain (RuBisCO_large)	Ribulose bisphosphate carboxylase large chain, catalytic domain	The C-terminal domain of RuBisCO large chain is the catalytic domain adopting a TIM barrel fold.	Domain
E [auth I], F [auth K], G [auth M], H [auth O]	PF00101	Ribulose bisphosphate carboxylase, small chain (RuBisCO_small)	Ribulose bisphosphate carboxylase, small chain	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B [auth C], C [auth E], D [auth G]	RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE LARGE CHAIN	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding ribulose-bisphosphate carboxylase activity carboxy-lyase activity lyase activity catalytic activity carbon-carbon lyase activity monooxygenase activity oxidoreductase activity	metabolic process cellular process cellular metabolic compound salvage photorespiration carbohydrate metabolic process biosynthetic process photosynthesis reductive pentose-phosphate cycle carbohydrate biosynthetic process photosynthesis, dark reaction primary metabolic process carbon fixation	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure plastid organelle cytoplasm intracellular membrane-bounded organelle chloroplast
E [auth I], F [auth K], G [auth M], H [auth O]	RIBULOSE BISPHOSPHATE CARBOXYLASE SMALL CHAIN 1	ribulose-bisphosphate carboxylase activity carboxy-lyase activity lyase activity catalytic activity carbon-carbon lyase activity	metabolic process cellular process cellular metabolic compound salvage photorespiration carbohydrate metabolic process biosynthetic process photosynthesis reductive pentose-phosphate cycle carbohydrate biosynthetic process photosynthesis, dark reaction primary metabolic process carbon fixation	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure plastid organelle cytoplasm intracellular membrane-bounded organelle chloroplast

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B [auth C], C [auth E], D [auth G]	IPR020888	Ribulose bisphosphate carboxylase large subunit, type I	Family
A, B [auth C], C [auth E], D [auth G]	IPR036376	Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily	Homologous Superfamily
A, B [auth C], C [auth E], D [auth G]	IPR020878	Ribulose bisphosphate carboxylase, large chain, active site	Active Site
A, B [auth C], C [auth E], D [auth G]	IPR000685	Ribulose bisphosphate carboxylase, large subunit, C-terminal	Domain
A, B [auth C], C [auth E], D [auth G]	IPR033966	RuBisCO	Family
A, B [auth C], C [auth E], D [auth G]	IPR017443	Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal	Domain
A, B [auth C], C [auth E], D [auth G]	IPR036422	RuBisCO large subunit, N-terminal domain superfamily	Homologous Superfamily
E [auth I], F [auth K], G [auth M], H [auth O]	IPR036385	Ribulose bisphosphate carboxylase, small subunit superfamily	Homologous Superfamily
E [auth I], F [auth K], G [auth M], H [auth O]	IPR024681	Ribulose bisphosphate carboxylase, small subunit	Family
E [auth I], F [auth K], G [auth M], H [auth O]	IPR000894	Ribulose bisphosphate carboxylase small subunit, domain	Domain

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A, B [auth C], C [auth E], D [auth G]	HYP	Parent Component: PRO RESID: AA0030 PSI-MOD : 4-hydroxy-L-proline MOD:00039
A, B [auth C], C [auth E], D [auth G]	KCX	Parent Component: LYS RESID: AA0030
A, B [auth C], C [auth E], D [auth G]	SMC	Parent Component: CYS RESID: AA0030 , AA0234 PSI-MOD : 4-hydroxy-L-proline MOD:00039 , S-methyl-L-cysteine MOD:00239
E [auth I], F [auth K], G [auth M], H [auth O]	MME	Parent Component: MET RESID: AA0030 , AA0234 , AA0064 PSI-MOD : 4-hydroxy-L-proline MOD:00039 , S-methyl-L-cysteine MOD:00239 , N-methyl-L-methionine MOD:00073

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.