Annotations: 9GSZ

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF07690	Major Facilitator Superfamily (MFS_1)	Major Facilitator Superfamily	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Monocarboxylate transporter 10	L-amino acid transmembrane transporter activity amino acid transmembrane transporter activity aromatic amino acid transmembrane transporter activity organic cation transmembrane transporter activity transporter activity carboxylic acid transmembrane transporter activity organic acid transmembrane transporter activity L-tyrosine transmembrane transporter activity transmembrane transporter activity organic anion transmembrane transporter activity active transmembrane transporter activity thyroid hormone transmembrane transporter activity secondary active transmembrane transporter activity L-tryptophan transmembrane transporter activity L-amino acid transmembrane transporter activity amino acid transmembrane transporter activity aromatic amino acid transmembrane transporter activity organic cation transmembrane transporter activity transporter activity carboxylic acid transmembrane transporter activity organic acid transmembrane transporter activity L-tyrosine transmembrane transporter activity transmembrane transporter activity organic anion transmembrane transporter activity active transmembrane transporter activity thyroid hormone transmembrane transporter activity secondary active transmembrane transporter activity L-tryptophan transmembrane transporter activity L-phenylalanine transmembrane transporter activity	regulation of hormone levels phenol-containing compound metabolic process biological regulation modified amino acid metabolic process metabolic process cellular process regulation of biological quality hormone metabolic process thyroid hormone generation thyroid hormone metabolic process organic acid transport localization aromatic amino acid transport nitrogen compound transport regulation of hormone levels phenol-containing compound metabolic process biological regulation modified amino acid metabolic process metabolic process cellular process regulation of biological quality hormone metabolic process thyroid hormone generation thyroid hormone metabolic process organic acid transport localization aromatic amino acid transport nitrogen compound transport organic anion transport carboxylic acid transport transport establishment of localization thyroid hormone transport hormone transport amino acid transport signaling hormone secretion cell communication peptide secretion secretion by cell amide transport signal release regulation of biological process secretion thyroid-stimulating hormone secretion cell-cell signaling export from cell peptide transport peptide hormone secretion	cellular anatomical structure cell junction cell periphery plasma membrane membrane basal part of cell basal plasma membrane plasma membrane region basolateral plasma membrane membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR011701	Major facilitator superfamily	Family
A	IPR050327	Proton-linked Monocarboxylate Transporter	Family
A	IPR036259	MFS transporter superfamily	Homologous Superfamily
A	IPR020846	Major facilitator superfamily domain	Domain

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: Q8TF71	acute myeloid leukemia atypical teratoid rhabdoid tumor interstitial cystitis malignant ependymoma pancreatic ductal adenocarcinoma pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia skin disease Allan-Herndon-Dudley syndrome cutaneous lupus erythematosus invasive ductal breast carcinoma malignant pancreatic neoplasm pancreatic intraductal papillary-mucinous carcinoma psoriasis tuberculosis atopic eczema acute myeloid leukemia atypical teratoid rhabdoid tumor interstitial cystitis malignant ependymoma pancreatic ductal adenocarcinoma pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia skin disease Allan-Herndon-Dudley syndrome cutaneous lupus erythematosus invasive ductal breast carcinoma malignant pancreatic neoplasm pancreatic intraductal papillary-mucinous carcinoma psoriasis tuberculosis atopic eczema gastric carcinoma lung carcinoma ovarian cancer pancreatic intraductal papillary-mucinous neoplasm sarcoidosis

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A	MemProtMD	Annotated as membrane protein by MemProtMD

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.