Download MendeleyHuman monocarboxylate 10 bound to L-thyroxine
Coscia, F., Tassinari, M.To be published.
9GSZ | pdb_00009gsz
Human monocarboxylate transporter 10 bound to L-thyroxine
- PDB DOI: https://doi.org/10.2210/pdb9GSZ/pdb
- EM Map EMD-51559: EMDB EMDataResource
- Classification: TRANSPORT PROTEIN
- Organism(s): Homo sapiens
- Expression System: Homo sapiens
- Mutation(s): No
- Deposited: 2024-09-16 Released: 2025-05-21
- Funding Organization(s): European Research Council (ERC)
Experimental Data Snapshot
- Method: ELECTRON MICROSCOPY
- Resolution: 3.80 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
Starting Model: in silico
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wwPDB Validation 3D Report Full Report
This is version 1.0 of the entry. See complete history.
Literature
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Monocarboxylate transporter 10 | 493 | Homo sapiens | Mutation(s): 0 Gene Names: SLC16A10, MCT10, TAT1 |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q8TF71 (Homo sapiens) Explore Q8TF71 Go to UniProtKB: Q8TF71 | |||||
PHAROS: Q8TF71 GTEx: ENSG00000112394 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q8TF71 | ||||
Sequence AnnotationsExpand | |||||
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Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| T44 (Subject of Investigation/LOI) Query on T44 | B [auth A] | 3,5,3',5'-TETRAIODO-L-THYRONINE C15 H11 I4 N O4 XUIIKFGFIJCVMT-LBPRGKRZSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: ELECTRON MICROSCOPY
- Resolution: 3.80 Å
- Aggregation State: PARTICLE
- Reconstruction Method: SINGLE PARTICLE
| Task | Software Package | Version |
|---|---|---|
| MODEL REFINEMENT | PHENIX | 1.20.1_4487: |
Entry History & Funding Information
Deposition Data
- Released Date: 2025-05-21 Deposition Author(s): Coscia, F., Tassinari, M.
| Funding Organization | Location | Grant Number |
|---|---|---|
| European Research Council (ERC) | European Union | 101041298 |
Revision History (Full details and data files)
- Version 1.0: 2025-05-21
Type: Initial release
