Download MendeleyCRYSTAL STRUCTURE OF CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH DIFFERENT SUBSTRATES AND ONE INHIBITOR.
Kerff, F., Fonze, E., Sauvage, E., Frere, J.M., Charlier, P.To be published.
1K6R
STRUCTURE OF THE CLASS D BETA-LACTAMASE OXA-10 IN COMPLEX WITH MOXALACTAM
- PDB DOI: https://doi.org/10.2210/pdb1K6R/pdb
- Classification: HYDROLASE
- Organism(s): Pseudomonas aeruginosa
- Expression System: Escherichia coli BL21(DE3)
- Mutation(s): No
- Deposited: 2001-10-17 Released: 2003-06-24
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 ?
- R-Value Free: 0.237
- R-Value Work: 0.198
- R-Value Observed: 0.198
Starting Model: experimental
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This is version 1.5 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Beta-lactamase PSE-2 | 248 | Pseudomonas aeruginosa | Mutation(s): 0 Gene Names: plasmid pMON234 EC: 3.5.2.6 |  | |
UniProt | |||||
Find proteins for P14489 (Pseudomonas aeruginosa) Explore P14489 Go to UniProtKB: P14489 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | P14489 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 1 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| MX1 Query on MX1 | C [auth A], D [auth B] | (2R)-2-((R)-CARBOXY{[CARBOXY(4-HYDROXYPHENYL)ACETYL]AMINO}METHOXYMETHYL)-5-METHYLENE-5,6-DIHYDRO-2H-1,3-OXAZINE-4-CARBO
XYLIC ACID C18 H18 N2 O10 ZTOQXKUYWZBJLG-XNAIMREJSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.30 ?
- R-Value Free: 0.237
- R-Value Work: 0.198
- R-Value Observed: 0.198
- Space Group: P 21 21 21
Unit Cell:
| Length ( ? ) | Angle ( ? ) |
|---|---|
| a = 48.706 | ¦Á = 90 |
| b = 96.003 | ¦Â = 90 |
| c = 125.195 | ¦Ă = 90 |
| Software Name | Purpose |
|---|---|
| MOSFLM | data reduction |
| SCALA | data scaling |
| AMoRE | phasing |
| CNS | refinement |
| CCP4 | data scaling |
Entry History
Deposition Data
- Released Date: 2003-06-24 Deposition Author(s): Kerff, F., Fonze, E., Sauvage, E., Frere, J.M., Charlier, P.
Revision History (Full details and data files)
- Version 1.0: 2003-06-24
Type: Initial release - Version 1.1: 2008-04-27
Changes: Version format compliance - Version 1.2: 2011-07-13
Changes: Version format compliance - Version 1.3: 2011-08-31
Changes: Non-polymer description - Version 1.4: 2023-08-16
Changes: Data collection, Database references, Derived calculations, Refinement description, Structure summary - Version 1.5: 2024-10-16
Changes: Structure summary
